Results 271 to 280 of about 70,452 (309)

C-reactive protein: the nexus between inflammation and protein misfolding diseases. [PDF]

Front Immunol
Roy A, Zeller J, Nero TL, Klepetko J, Eisenhardt SU, Parker MW, McFadyen JD, Peter K.   +7 more
europepmc   +1 more source

Macrophage C1q contributes to pulmonary fibrosis by disturbing the metabolism of alveolar epithelial cells. [PDF]

Clin Transl Med
Prüfer F, Steer B, Kaufmann E, Wolf P, Adler B, Korfei M, Günther A, Königshoff M, Adler H.   +8 more
europepmc   +1 more source

C1q⁺ Macrophage-Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma. [PDF]

Adv Sci (Weinh)
Liu Y, Huang C, Luo M, Lu W, Zhang B, Bai L, Zheng S, Tan Y, Li S, Wang H, Gong L, Guan X.   +11 more
europepmc   +1 more source

Correction to "Results From a Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of ANX005, a C1q Inhibitor, in Patients With Guillain-Barré Syndrome". [PDF]

J Peripher Nerv Syst
europepmc   +1 more source

Vaccine-induced antibodies are sufficient to limit Salmonella infection in the absence of complement or macrophages

Perez-Toledo M, Aksu-Istil K, Marcial-Juarez E, Persaud RR, Alshayea A, Jossi SE, Carestia A, von Meijenfeld F, Botto M, James LC, Sureward B, Horsnell WH, Lopez-Macias C, Henderson IR, OptiVaNTS consortium, Jenne CN, Cunningham AF.   +16 more
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Paeoniflorin prevents aberrant proliferation and differentiation of intestinal stem cells by controlling C1q release from macrophages in chronic colitis.

Pharmacological Research, 2022
The pathological features of inflammatory bowel disease necessitate therapeutic strategies aimed at restoring intestinal mucosal barrier function in addition to controlling inflammation. Paeoniflorin, a bioactive herbal constituent isolated from the root
Yirui Wang, Keyuan You, Yan You, Qian Li, Gui-ze Feng, Jiahui Ni, Xinyue Cao, Xiaowen Zhang, Yan-hang Wang, Weilian Bao, Xu Wang, Tongqing Chen, Haidong Li, Yuran Huang, Jiaren Lyu, Shi Yu, Hong Li, Suowen Xu, Kewu Zeng, Xiaoyan Shen   +19 more
semanticscholar   +1 more source

C1q, antibodies and anti-C1q autoantibodies

Molecular Immunology, 2015
The complement system has long been known for its role in combating infections. More recently the complement system is becoming increasingly appreciated for its role in processes that range from waste transport, immune tolerance and shaping of the adaptive immune response.
Beurskens, F.J., Schaarenburg, R.A. van, Trouw, L.A.   +2 more
openaire   +4 more sources

C1q-binding proteins and C1q receptors

Current Opinion in Immunology, 1999
Aggregated or immobilized complement C1q induces cellular responses in many different cell types. C1q-induced cellular responses may be involved in host defense and in protection against autoimmunity because C1q-deficient humans have infectious complications and a very high incidence of autoimmune disease.
Lloyd B. Klickstein, Anne Nicholson-Weller   +1 more
openaire   +3 more sources

Macrophage C1q: characterization of a membrane form of C1q and of multimers of C1q subunits.

The Journal of Immunology, 1987
Abstract It has been shown recently that C1q, a subcomponent of the first component of the classical complement pathway, is synthesized by macrophages and that endogenous C1q is detectable on the macrophage membrane. In this report, we demonstrate that membrane-associated C1q, which contains the A, B, and C chains of C1q ...
H, Martin, H P, Heinz, K, Reske, M, Loos
openaire   +2 more sources