Results 161 to 170 of about 42,643 (266)
Encoding Cell‐Surface Receptor Function Through Glycosylation: Lessons From CD44
CD44 function is not solely determined by its protein sequence, it is dynamically encoded by its glycosylation state. Glycan remodeling generates distinct functional receptor states that regulate ligand recognition, receptor organization, lectin interactions, and signaling.
María Payá‐García +7 more
wiley +1 more source
Synthesis, Characterization and Reactivity of Alkyl Iron(II) PCP Pincer Complexes. [PDF]
Käfer M +5 more
europepmc +1 more source
Hitting Coronaviruses Where It Hurts: Antiviral Strategies Targeting Viral Proteins
Viral proteins represent key vulnerabilities in human coronaviruses (HCoVs). This review outlines inhibitors targeting spike (S), main protease (Mpro), papain‐like protease (PLpro), and RNA‐dependent RNA polymerase (RdRp), mapping chemically diverse strategies that disrupt entry and replication, and provides an integrated view of current candidates ...
Álvaro de la Cruz‐Potenciano +3 more
wiley +1 more source
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte +21 more
wiley +1 more source
Chlorido-((<i>E</i>)-2-{2-[(2-hy-droxy-benzyl-idene)amino]-2-(pyridin-2-yl)-1-[(pyridin-2-ylmeth-yl)amino]eth-yl}phenolato-κ<sup>4</sup> <i>N</i>,<i>N</i>',<i>N</i>'',<i>O</i>)copper(II). [PDF]
Alkhamis K, Gultneh Y, Butcher RJ.
europepmc +1 more source
A circular upcycling strategy transforms waste poly(ethylene terephthalate) bottles into microwave‐responsive Ni@C catalyst featuring lattice‐distorted nickel cores and defective carbon shells. These strain‐rich heterointerfaces enhance dielectric loss and promote localized microwave hotspots, accelerating peroxymonosulfate activation and polymer‐chain
Xiao Lu +7 more
wiley +1 more source

