Results 101 to 110 of about 4,044,136 (204)

Structure of the C-terminal domain of AspA (antigen I/II-family) protein from Streptococcus pyogenes

FEBS Open Bio, 2014
The pathogenic bacteria Streptococcus pyogenes can cause an array of diseases in humans, including moderate infections such as pharyngitis (strep throat) as well as life threatening conditions such as necrotizing fasciitis and puerperal fever.
Michael Hall, Åsa Nylander, Howard F. Jenkinson, Karina Persson   +3 more
doaj   +1 more source

Pivotal Role of the C2 Domain of the Smurf1 Ubiquitin Ligase in Substrate Selection*♦

Journal of Biological Chemistry, 2011
The C2-WW-HECT-type ubiquitin ligases Smurf1 and Smurf2 play a critical role in embryogenesis and adult bone homeostasis via regulation of bone morphogenetic protein, Wnt, and RhoA signaling pathways.
Kefeng Lu, Ping Li, Minghua Zhang, G. Xing, Xin Li, Weihong Zhou, M. Bartlam, Lingqiang Zhang, Z. Rao, F. He   +9 more
semanticscholar   +1 more source

Rescue of HIV-1 release by targeting widely divergent NEDD4-type ubiquitin ligases and isolated catalytic HECT domains to Gag.

PLoS Pathogens, 2010
Retroviruses engage the ESCRT pathway through late assembly (L) domains in Gag to promote virus release. HIV-1 uses a PTAP motif as its primary L domain, which interacts with the ESCRT-I component Tsg101. In contrast, certain other retroviruses primarily
Eric R Weiss, Elena Popova, Hikaru Yamanaka, Hyung Cheol Kim, Jon M Huibregtse, Heinrich Göttlinger   +5 more
doaj   +1 more source

Cc2d1a, a C2 domain containing protein linked to nonsyndromic mental retardation, controls functional maturation of central synapses.

Journal of Neurophysiology, 2011
Cc2d1a is an evolutionarily conserved protein composed of NH(2)-terminal Drosophila melanogaster 14 domain (DM14) domains and a COOH-terminal C2 domain.
Meng Zhao, J. Raingo, Zhijian J. Chen, E. Kavalali   +3 more
semanticscholar   +1 more source

The Nedd4L ubiquitin ligase is activated by FCHO2-generated membrane curvature

The EMBO Journal
The C2-WW-HECT domain ubiquitin ligase Nedd4L regulates membrane sorting during endocytosis through the ubiquitination of cargo molecules such as the epithelial sodium channel (ENaC). Nedd4L is catalytically autoinhibited by an intramolecular interaction
Yasuhisa Sakamoto, Akiyoshi Uezu, Koji Kikuchi, Jangmi Kang, Eiko Fujii, Toshiro Moroishi, Shiro Suetsugu, Hiroyuki Nakanishi   +7 more
doaj   +1 more source

The major myosin-binding domain of skeletal muscle MyBP-C (C protein) resides in the COOH-terminal, immunoglobulin C2 motif. [PDF]

, 1993
A common feature shared by myosin-binding proteins from a wide variety of species is the presence of a variable number of related internal motifs homologous to either the Ig C2 or the fibronectin (Fn) type III repeats.
Fischman, DA, Mikawa, T, Okagaki, T, Reinach, FC, Vaughan, KT, Weber, FE   +5 more
core  

From biophysical interaction to structural modeling: bi-terminal G and TGS domains drive rice OsYchF1-OsGAP1 complex formation

Botanical Studies
OsYchF1 belongs to the YchF subfamily in the Obg family of G proteins, and comprises a core G domain, an α-helical domain, and a TGS domain from the N-terminus to the C-terminus.
Suchang Huang, Ziting Wu, Kuang Wang, Yunchuan Liao, Jiaqiang Zeng, Rui Miao   +5 more
doaj   +1 more source

Infrared phonon spectra of quasi-one-dimensional Ta$_2$NiSe$_5$ and Ta$_2$NiS$_5$

, 2018
Using a combination of infrared ellipsometry, time-domain terahertz spectroscopy, and far-infrared reflectometry we have obtained the $ac$-plane complex dielectric function of monoclinic ($C2/c$) Ta$_2$NiSe$_5$ and orthorhombic ($Cmcm$) Ta$_2$NiS$_5 ...
Boris, A. V., Dawson, R. D., Höppner, M., Isobe, M., Keimer, B., Larkin, T. I., Mathis, Y. -L., Takagi, H., Takayama, T.   +8 more
core   +1 more source

Analysis of the complete genome of hepatitis B virus subgenotype C2 isolate NHB17965 from a patient with uncomplicated chronicity [version 2; referees: 2 approved, 1 approved with reservations]

F1000Research, 2018
The burden of chronic hepatitis B virus (HBV) infections is increasingly detected nowadays. Herein, we report a complete genome of HBV subgenotype C2 (HBV/C2) from a patient with chronic HBV infection.
Modhusudon Shaha, Palash Kumar Sarker, Md. Saddam Hossain, Keshob Chandra Das, Munira Jahan, Shuvra Kanti Dey, Shahina Tabassum, Abu Hashem, Md. Salimullah   +8 more
doaj   +1 more source

Structural basis of ubiquitin ligase Nedd4-2 autoinhibition and regulation by calcium and 14-3-3 proteins

Nature Communications
Nedd4-2 E3 ligase regulates Na+ homeostasis by ubiquitinating various channels and membrane transporters, including the epithelial sodium channel ENaC.
Masa Janosev, Dalibor Kosek, Andrej Tekel, Rohit Joshi, Karolina Honzejkova, Pavel Pohl, Tomas Obsil, Veronika Obsilova   +7 more
doaj   +1 more source