Results 71 to 80 of about 157,920 (289)

Exciton Binding Energy of Phosphorescent Emitter Molecules in Organic Light‐Emitting Diodes

open access: yesAdvanced Functional Materials, EarlyView.
Energy level alignment is key to efficient OLED design, yet determining LUMO energies remains challenging. A methodology based on field‐induced dissociation and kinetic Monte Carlo simulations is presented to extract LUMO energies of iridium‐based phosphorescent emitters from their exciton binding energy.
Hiroki Tomita   +6 more
wiley   +1 more source

Modulation of Factor V Levels in Plasma by Polymorphisms in the C2 Domain [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2004
Objective—Functional polymorphisms contributing to coagulation factor levels are preferential markers for association studies aimed at identifying prothrombic genetic components.Methods and Results—Factor V (FV) microsatellite genotypes were found to be associated with FV levels (P=0.003).
SCANAVINI, Daniela   +7 more
openaire   +6 more sources

Membrane domain formation by calcium-dependent, lipid-binding proteins: insights from the C2 motif [PDF]

open access: yes, 1998
We propose a novel role in cellular function for some membrane-binding proteins and, specifically, the C2 motif. The C2 motif binds phospholipid in a manner that is modulated by Ca2+ and is thought to confer membrane-binding ability on a wide variety of ...
Paulo F.F. Almeida   +8 more
core   +1 more source

A Molecular Shielding Strategy to Develop Low Protein Binding, Renal Clearable Pan‐Cancer Near‐Infrared Probes

open access: yesAdvanced Functional Materials, EarlyView.
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang   +9 more
wiley   +1 more source

PTEN controls glandular morphogenesis through a juxtamembrane β-Arrestin1/ARHGAP21 scaffolding complex

open access: yeseLife, 2017
PTEN controls three-dimensional (3D) glandular morphogenesis by coupling juxtamembrane signaling to mitotic spindle machinery. While molecular mechanisms remain unclear, PTEN interacts through its C2 membrane-binding domain with the scaffold protein β ...
Arman Javadi   +6 more
doaj   +1 more source

Trace Sulfur‐Doping Boosts NiCo Heterostructured Catalyst for Selective Glycerol‐to‐Formic Acid Electroreforming

open access: yesAdvanced Functional Materials, EarlyView.
A sulfur‐doped Ni–Co heterostructured catalyst is rationally designed to regulate interfacial electronic and adsorption properties for selective glycerol electrooxidation. The synergistic Ni–Co active sites promote hydroxide activation and glycerol adsorption, enabling efficient formic acid production and durable hydrogen generation under continuous ...
Lingqin Shen   +4 more
wiley   +1 more source

Regulation of PKCα Activity by C1-C2 Domain Interactions [PDF]

open access: yesJournal of Biological Chemistry, 2002
In this study, the role of interdomain interactions involving the C1 and C2 domains in the mechanism of activation of PKC was investigated. Using an in vitro assay containing only purified recombinant proteins and the phorbol ester, 4 beta-12-O-tetradecanoylphorbol-13-acetate (TPA), but lacking lipids, it was found that PKC alpha bound specifically ...
Simon J, Slater   +7 more
openaire   +2 more sources

Digitizing the Filtration Interface: A Smart, Modular Janus Wood Platform for Self‐Reporting Oil/Water Remediation

open access: yesAdvanced Functional Materials, EarlyView.
This work developed a smart Janus wood membrane integrating asymmetric wettability with built‐in electrical sensing for oil‐water separation. The membrane achieved > 99.5% separation efficiency and high flux by leveraging wood's natural anisotropic pore structure.
Kaiwen Chen   +10 more
wiley   +1 more source

RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes.

open access: yesPLoS Genetics, 2016
EHBP-1 (Ehbp1) is a conserved regulator of endocytic recycling, acting as an effector of small GTPases including RAB-10 (Rab10). Here we present evidence that EHBP-1 associates with tubular endosomal phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2 ...
Peixiang Wang   +9 more
doaj   +1 more source

Structural basis for interdomain communication in SHIP2 providing high phosphatase activity

open access: yeseLife, 2017
SH2-containing-inositol-5-phosphatases (SHIPs) dephosphorylate the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3) and play important roles in regulating the PI3K/Akt pathway in physiology and disease.
Johanne Le Coq   +7 more
doaj   +1 more source

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