Results 41 to 50 of about 27,277 (237)
Brain Pathology, 2020 Neuroinflammation is thought to play a pivotal role in the pathogenesis of periventricular white matter (PWM) damage (PWMD) induced by neonatal sepsis. Because the complement cascade is implicated in inflammatory response, this study was carried out to ...
Peixian Huang +8 more
semanticscholar +1 more source
Trends in Ocean S‐Isotopes May Be Influenced by Major LIP Events
Geophysical Monograph Series, Page 341-376., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Ross. R. Large +5 more
wiley +1 more source
Vibrational Signals for Mating Disruption Do Not Negatively Affect Grapevine Growth and Production
Australian Journal of Grape and Wine ResearchVibrational mating disruption (VMD) is a promising strategy to control Scaphoideus titanus populations in vineyards, and it is based on the prolonged application of a species-specific disturbance vibrational signal (DVS) on grapevines.
Stefano Galvagni +6 more
doaj +1 more source
C3a Enhances the Formation of Intestinal Organoids through C3aR1
Frontiers in Immunology, 2017 C3a is important in the regulation of the immune response as well as in the development of organ inflammation and injury. Furthermore, C3a contributes to liver regeneration but its role in intestinal stem cell function has not been studied.
Naoya Matsumoto +7 more
doaj +1 more source
Advanced Science, EarlyView.We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang +14 more
wiley +1 more source
Mediators of Inflammation, 2020 The purpose of the current study was to explore the effect of autologous adipose tissue on cartilage responses to lipopolysaccharide (LPS). We hypothesized that LPS elicits an inflammatory response in cartilage, and that response is augmented in the ...
Wendy Pearson +4 more
doaj +1 more source
Navigating adverse immunostimulation: A practical guide for clinical researchers
British Journal of Clinical Pharmacology, EarlyView.Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort +8 more
wiley +1 more source
Impact of using yeast derivatives on the development of atypical aging in wines
OENO OneYeast derivatives (YDs) are commercial products obtained from yeast colonies grown in bioreactors then inactivated and dried. They are employed in winemaking to supply nitrogen (N), enhance yeast growth and remove unwanted compounds.
Simone Delaiti +6 more
doaj +1 more source
Journal of Materials Research and Technology, 2023 The role of ion diffusion in the heat flow and chemical shrinkage of tricalcium aluminate (C3A) hydration was investigated using the proposed multi-ionic reactive transport model for C3A hydration.
Yang Liu +5 more
doaj +1 more source