Results 111 to 120 of about 3,935,620 (190)

Targeting complement C3a receptor resolves mitochondrial hyperfusion and subretinal microglial activation in progranulin-deficient frontotemporal dementia

bioRxiv
Li Tan, F. Oertel, An Cheng, Y. Cobigo, Azeen Keihani, Daniel J. Bennett, A. Abdelhak, S. C. Montes, Makenna Chapman, Robert Y. Chen, C. Cordano, Michael E. Ward, K. Casaletto, J. Kramer, H. Rosen, A. Boxer, Bruce L. Miller, Ari J. Green, F. Elahi, A. Lakkaraju   +19 more
semanticscholar   +1 more source

Correction: C3a receptor signaling inhibits neurodegeneration induced by neonatal hypoxic-ischemic brain injury. [PDF]

Front Immunol
Pozo-Rodrigálvarez A, Li Y, Stokowska A, Wu J, Dehm V, Sourkova H, Steinbusch H, Mallard C, Hagberg H, Pekny M, Pekna M.   +10 more
europepmc   +1 more source

Adipsin and adipocyte-derived C3aR1 regulate thermogenic fat in a sex-dependent fashion

JCI Insight
Thermogenesis in beige/brown adipose tissues can be leveraged to combat metabolic disorders such as type 2 diabetes and obesity. The complement system plays pleiotropic roles in metabolic homeostasis and organismal energy balance with canonical effects ...
Lunkun Ma, Ankit Gilani, Alfonso Rubio-Navarro, Eric Cortada, Ang Li, Shannon M. Reilly, Liling Tang, James C. Lo   +7 more
doaj   +1 more source

VGF and the VGF-derived peptide AQEE30 stimulate osteoblastic bone formation through the C3a receptor. [PDF]

Exp Mol Med
Moon SA, Kim JM, Lee YS, Cho HJ, Choi YJ, Yoon JH, Kim D, Che X, Jin X, Baek IJ, Lee SH, Choi JY, Koh JM.   +12 more
europepmc   +1 more source

Anaphylatoxins in the pathogenesis of asthma

Respiratory Research, 2000
Heinzmann Andrea, Bautsch W, Hoymann HG, Zhang Q, Meier-Wiedenbach I, Raschke U, Ames RS, Sohns B, Flemme N, Meyer zu Vilsendorf A, Grove M, Klos A, Kohl J   +12 more
doaj   +1 more source

How complement activation via a C3a receptor pathway alters CD4+ T lymphocytes and mediates lung cancer progression?-future perspectives. [PDF]

J Thorac Dis, 2019
Magalhães Filho M, Aguiar Junior PN, Adashek JJ, De Mello RA.   +3 more
europepmc   +1 more source

The Complement C3a Receptor Contributes to Melanoma Tumorigenesis by Inhibiting Neutrophil and CD4+ T Cell Responses

Journal of Immunology, 2016
J. Nabizadeh, H. Manthey, F. Steyn, Wei-Yu Chen, A. Widiapradja, F. N. Md Akhir, G. Boyle, S. Taylor, T. Woodruff, B. Rolfe   +9 more
semanticscholar   +1 more source

Potent complement C3a receptor agonists derived from oxazole amino acids: Structure-activity relationships.

Bioorganic & Medicinal Chemistry Letters, 2015
Ranee Singh, Anthony N Reed, P. Chu, Conor C. G. Scully, Mei-Kwan Yau, J. Suen, T. Durek, R. Reid, D. Fairlie   +8 more
semanticscholar   +1 more source

The complement C3a receptor is critical in defense against Chlamydia psittaci in mouse lung infection and required for antibody and optimal T cell response.

Journal of Infectious Diseases, 2014
P. Dutow, B. Fehlhaber, J. Bode, Robert Laudeley, C. Rheinheimer, S. Glage, R. Wetsel, O. Pabst, A. Klos   +8 more
semanticscholar   +1 more source

Complement Proteins C1q-C5 as Context‑Dependent Regulators of Osteoblast Function and Fracture Healing: A Systematic Review. [PDF]

Orthop Rev (Pavia)
Counts PR, Baer TM, Viswanath O, Ganti L.   +3 more
europepmc   +1 more source