Results 151 to 160 of about 2,660,664 (273)

Cutting Edge: Receptors for C3a and C5a Modulate Stability of Alloantigen-Reactive Induced Regulatory T Cells [PDF]

, 2013
William van der Touw, Paolo Cravedi, W. H. Kwan, Estela Paz‐Artal, Miriam Mérad, Peter S. Heeger   +5 more
openalex   +1 more source

Reaction Pathways in the (De)hydrogenation of N‐Heterocyclic Liquid Hydrogen Carriers Over Supported Pd Catalysts

ChemSusChem, Volume 19, Issue 10, 27 May 2026.
Indoles are promising N‐heterocyclic liquid organic hydrogen carriers. Here, we investigate the reaction pathways of (methyl)indole (de)hydrogenation over Pd catalysts using reaction experiments and computational modeling: we show that distinct intermediates are formed in hydrogenation versus dehydrogenation steps, and stereocenter evolution is ...
Matthew D. Edgar, Fujie Lan, Sara Ahsan, Grace Zhang, Genevieve E. Ansay, Brandon C. Bukowski, Siddarth H. Krishna   +6 more
wiley   +1 more source

Role of the complement components C5 and C3a in a mouse model of myocardial ischemia and reperfusion injury

GMS German Medical Science, 2010
Objective: Ischemic heart disease is the leading cause of death worldwide. The complement system plays a major role in inflammation and tissue injury following myocardial ischemia and reperfusion (MI/R) injury.
Stahl, Gregory L., Busche, Marc N.
doaj  

“Reactions in Leprosy: Updated Insights Into Pathophysiology, Clinical Spectrum, and Therapeutic Approaches—A Narrative Review”

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Reaction in leprosy is an immune‐mediated acute inflammatory episodes that occur in the natural course of Hansen's disease. Reaction can occur before, during, or after starting multidrug therapy and is a major cause of nerve damage, morbidity, and disability in affected individuals.
Bhaskar Gupta, Manesha Singh, Mohamad Goldust, Kinnor Das, Surajit Gorai, Prajwal Pudasaini, Seema Sitaula, Achyut Pokhrel, Esna Thapa, Sunil Jaiswal   +9 more
wiley   +1 more source

Nanofibrous Platforms for Advanced Wound Therapeutics: Mechanisms, Materials, and Clinical Horizons

Macromolecular Bioscience, Volume 26, Issue 5, May 2026.
The fabrication of nanofiber dressings from diverse natural and synthetic polymers offers a robust platform for chronic wound management. By encapsulating therapeutic drugs and bioactive agents, these dressings can simultaneously attenuate chronic inflammation and microbial infection while actively stimulating angiogenesis, addressing the primary ...
Wanho Cho, Chungmo Yang, Hyuk Sang Yoo
wiley   +1 more source

CD44ICD promotes breast cancer stemness via PFKFB4-mediated glucose metabolism. [PDF]

, 2018
CD44 is a single-pass cell surface glycoprotein that is distinguished as the first molecule used to identify cancer stem cells in solid tumors based on its expression.
Gao, Ruifang, Li, Dan, Li, Jun, Li, Xiru, Liu, Chen, Luo, Na, Qiao, Huan, Shen, Wenzhi, Stupack, Dwayne G, Wang, Juan, Xun, Jing, Zhou, Wei   +11 more
core  

Identification of a Selective Nonpeptide Antagonist of the Anaphylatoxin C3a Receptor That Demonstrates Antiinflammatory Activity in Animal Models [PDF]

, 2001
Robert S. Ames, Dennis Lee, James J. Foley, Anthony J. Jurewicz, Mark Tornetta, Wilfried Bautsch, Britta Settmacher, Andreas Klos, Karl F. Erhard, Russell D. Cousins, Anthony C. Sulpizio, J. Paul Hieble, Gerald P. McCafferty, Keith W. Ward, Jerry L. Adams, William E. Bondinell, David C. Underwood, Ruth R. Osborn, Alison M. Badger, Henry M. Sarau   +19 more
openalex   +1 more source

Az adaptív immunválasz kialakulása és szabályozása fiziológiás és kóros körülmények között: dendritikus sejtek, hízósejtek és a komplementrendszer szerepének vizsgálata = Regulation of adaptive immune responses under normal and pathological conditions; role of dendritic cells, mastocytes and the complement system [PDF]

, 2009
A magasabbrendű szervezetek immunhomeosztázisát a veleszületett és az adaptív immunrendszer együtt tartja fenn; egymással szorosan összefonódva, folyamatosan együttműködve.
Bajtay, Zsuzsa, Erdei, Anna, László, Glória, Prechl, József   +3 more
core  

Targeting Tumor Stroma: Current Challenges and Future Directions

MedComm, Volume 7, Issue 5, May 2026.
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang, Haofan Hu, Weifeng Zeng, Lu Qin, Xiaoping Chen, Zhibin Liao, Furong Liu, Zhanguo Zhang   +7 more
wiley   +1 more source

Deficiency of complement C3a and C5a receptors does not prevent angiotensin II–induced hypertension and hypertensive end-organ damage [PDF]

, 2023
Marlies Bode, Georg R. Herrnstadt, Leonie Dreher, Nicolas Ehnert, Pia Kirkerup, Maja T. Lindenmeyer, Catherine Meyer‐Schwesinger, Heimo Ehmke, Jörg Köhl, Tobias B. Huber, Thorsten Wiech, Ulrich Wenzel   +11 more
openalex   +1 more source