Results 61 to 70 of about 37,904 (214)

Molecular mechanism of complement inhibition by the trypanosome receptor ISG65

eLife
African trypanosomes replicate within infected mammals where they are exposed to the complement system. This system centres around complement C3, which is present in a soluble form in serum but becomes covalently deposited onto the surfaces of pathogens ...
Alexander D Cook, Mark Carrington, Matthew K Higgins   +2 more
doaj   +1 more source

Rough nonlocal diffusions [PDF]

, 2019
We consider a nonlinear Fokker-Planck equation driven by a deterministic rough path which describes the conditional probability of a McKean-Vlasov diffusion with "common" noise.
Coghi, Michele, Nilssen, Torstein
core   +3 more sources

Current Status of Kidney Xenotransplantation in Basic Research

Organ Medicine, EarlyView.
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley   +1 more source

Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. [PDF]

, 2018
Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and cancer. While p53 activation is responsible for many features of DBA, the role of immune system is less defined.
Bibikova, Elena, Danilova, Nadia, Lin, Shuo, Sakamoto, Kathleen M, Wilkes, Mark, Youn, Min-Young   +5 more
core   +2 more sources

Ba[C(CN)3]2 and Pb[C(CN)3]2: Two Remarkably Different Heavy Main‐Group Metal Bistricyanomethanides

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
Metathesis reactions of either barium dichloride, BaCl2, or lead dichloride, PbCl2, respectively, with Ag[C(CN)3] in water yielded single crystals of anhydrous Ba[C(CN)3]2 and Pb[C(CN)3]2. Ba[C(CN)3]2 crystallizes in the monoclinic space group P21/n (no. 14) with the lattice parameters a = 437.98(3) pm, b = 1685.36(11) pm, c = 1398.87(9) pm, β = 96.541(
Olaf Reckeweg, Ralf J. C. Locke, Falk Lissner, Lkhamsuren Bayarjargal, David Enseling, Thomas Jüstel, Thomas Schleid   +6 more
wiley   +1 more source

Swelling via Impedimetry Using Specifically Adhered Hydrogels on Co‐Planar Microfabricated Electrodes

Advanced Sensor Research
Responsive hydrogels adhered to microfabricated electrodes find applicability as chemical or biological sensors and in electro‐stimulated drug delivery.
Lauren V. Whitney, Sara Abasi, John R. Aggas, Anthony Guiseppi‐Elie   +3 more
doaj   +1 more source

Thrombomodulin enhances complement regulation through strong affinity interactions with factor H and C3b-Factor H complex [PDF]

, 2016
Introduction Coagulation and complement systems are simultaneously activated at sites of tissue injury, leading to thrombin generation and opsonisation with C3b.
Baerga-Ortiz, Bajzar, Boehme, Bossi, Campbell, Conway, de Córdoba S, Delvaeye, Dragon-Durey, Esmon, Esmon, Esmon, Esparza-Gordillo, Faust, Fuentes-Prior, Gordon, Hakobyan, Hamad, Harris, Heurich, Hindmarsh, Honda, Huntington, Ikeda, Ito, Jokiranta, Kavanagh, Li, Light, Maga, Markiewski, Martinez-Barricarte, Mayer, Meri, Mizuno, Moll, Morgan, Mouksassi, Noris, Owen, Pangburn, Sadler, Sadler, Saito, Salem, Sawada, Schramm, Shental-Bechor, Suzuki, Tateishi, Tortajada, Udagawa, Vincent, Walport, Walport, Wu, Yada, Yamamoto, Zushi   +58 more
core   +2 more sources

Bone Marrow Pathology in Cold Agglutinin‐Mediated Autoimmune Hemolytic Anemia: A Study of 56 Cases

European Journal of Haematology, EarlyView.
ABSTRACT Cold agglutinin disease (CAD) is a rare form of autoimmune hemolytic anemia (AIHA). CAD occurs in the context of a small clonal B‐cell lymphoproliferation restricted to blood and/or bone marrow (BM), without overt or extramedullary lymphoma. The WHO‐HAEM5 introduced a description of the CAD‐associated lymphoproliferative disorder (CAD‐LPD) in ...
Anne‐Marie L. Becking, Sophie J. Bernelot Moens, Marie José Kersten, Femke V. M. Mulder, Steven T. Pals, Lianne Koens, Josephine M. I. Vos   +6 more
wiley   +1 more source

Human complement factor H. Two factor H proteins are derived from alternatively spliced transcripts [PDF]

, 1991
The human complement factor H is an important component in the control of the alternative pathway of complement activation. We have previously shown that at least three factor H homologous mRNA species of 4.3 kb, 1.8 kb and 1.4 kb in length are ...
Alsenz, Alsenz, Aruffo, Chirgwin, Church, Conrad, Day, Feinberg, Fontaine, Kristensen, Laemmli, Maniatis, McAleer, Misasi, Pangburn, Ripoche, Schulz, Schulz, Schwaeble, Seed, Sim, Towbin, Whaley, Whaley   +23 more
core   +1 more source

Bridging the implementation gap in MCABC inventory management: from a taxonomy to practical archetypes

International Transactions in Operational Research, EarlyView.
Abstract Despite increasing demands for resilient and sustainable supply chains, inventory management often relies on outdated single‐criterion analyses. While multi‐criteria ABC (MCABC) analyses provide a theoretically mature assessment of resilience‐sustainability‐benefit trade‐offs in inventory, their adoption remains limited due to fragmented ...
Lukas Grützner, Michael H. Breitner
wiley   +1 more source