Results 81 to 90 of about 6,779 (207)

Complement Gene Variants Define the Conformational Dynamics of C3 Convertase

European Journal of Immunology, Volume 56, Issue 7, July 2026.
Multidisciplinary data have significantly advanced our understanding of C3bBb molecular dynamics. This review specifically contextualizes the functional impact of disease‐associated genetic variants, demonstrating that clinical genetics not only supports the current C3bBb model but also provides novel insights into previously undefined molecular ...
Héctor Martín Merinero, Seth J. Welsh, Zhen Xu, Richard J. H. Smith, Yuzhou Zhang   +4 more
wiley   +1 more source

Immune complexes and complement in serum and synovial fluid of rheumatoid arthritis patients [PDF]

Journal of Medical Biochemistry, 2009
Rheumatoid arthritis (RA) is predominantly an intraarticular inflammatory and autoimmune disease that involves different autoantibodies and effector mechanisms.
Mijušković Zoran, Rackov Ljiljana, Pejović Janko, Živanović Sandra, Stojanović Jelica, Kovačević Zoran   +5 more
doaj  

Assessing relational values of sacred landscapes through text mining of folktales: Insights from the Ryukyu Islands, Japan

People and Nature, Volume 8, Issue 7, Page 2383-2392, July 2026.
Abstract Assessing relational values of nature through its cultural and spiritual significance is crucial for effective nature conservation. Folktales offer insights into traditional relationships between people and nature, and text mining is a powerful tool for extracting information from textual datasets.
Naoki Saito, Soyo Takahashi, Akira Iguchi   +2 more
wiley   +1 more source

Baseline plasma C1q and C3 as potential biomarkers for lecanemab efficacy and ARIA risk in early Alzheimer's disease

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 3, July/September 2026.
Abstract INTRODUCTION The classical complement cascade has been implicated in amyloid beta (Aβ) clearance and in the pathogenesis of amyloid‐related imaging abnormalities (ARIA) during anti‐amyloid monoclonal antibody therapy. Clinically accessible peripheral biomarkers of this cascade remain uncharacterized in real‐world cohorts.
Gihwan Byeon, Jung‐Won Lee, Suhyung Kim, Yoo Hyun Um, Sheng‐Min Wang, Seunggyun Ha, Sonya Youngju Park, Ilah Shin, Jinhee Jang, Chang Uk Lee, Hyun Kook Lim, Dong Woo Kang   +11 more
wiley   +1 more source

Functional Hyperthermia Presenting as Fever of Unknown Origin With Normal Inflammatory Markers in an Adolescent

Journal of General and Family Medicine, Volume 27, Issue 5, September 2026.
Ryuichi Minoda Sada, Hirofumi Miyake, Hiroyuki Akebo, Kazuhiro Hatta   +3 more
wiley   +1 more source

Enhancing Turbulent Inflow Conditions for ABL LES Through Combined Synthetic and Perturbation Methods in PALM v6.0

Journal of Advances in Modeling Earth Systems, Volume 18, Issue 7, July 2026.
Abstract In large‐eddy simulations of the atmospheric boundary layer, insufficient inflow turbulence often requires long fetches, degrading accuracy and efficiency. To address this issue, we propose a new inflow turbulence generation approach that combines a digital‐filtering‐based synthetic turbulence generator (STG) with a cell perturbation method ...
Ju‐Wan Woo, Sang‐Hyun Lee
wiley   +1 more source

Transdisciplinarity in Serious Gaming Design for Improved Crisis Preparedness

International Journal of Serious Games
Transdisciplinarity is identified as an important paradigm to cope with the complexity of societal problems, such as public health crisis and climate change.
Francesca de Rosa, Mark Escott, Desmar Walkes, Douglas Havron, Lauren Ancel Meyers   +4 more
doaj   +1 more source

The relationship of anti-phospholipase A2 receptor antibody and C5a complement with disease activity and short-term outcome in idiopathic membranous nephropathy

Journal of the Formosan Medical Association, 2019
Background: The binding of anti-phospholipase A2 receptor (anti-PLA2R) antibody to podocyte and complement activation is the mechanisms of idiopathic membranous nephropathy (IMN).
Jyun Ni Chi, Tai Shuan Lai, Ching Fang Wu, Tian Yi Fu, Yu Hsiang Chou, Yen Ling Chiu, Wei Chou Lin, Wen Chih Chiang, Yung Ming Chen, Ming Shiou Wu   +9 more
doaj   +1 more source

Respuesta neuroinmunológica en niños con meningoencefalitis por Neisseria meningitidis

VacciMonitor, 2011
La enfermedad meningocócica es una entidad clínica que constituye aún un problema de salud mundial. Esta afecta, sobre todo, a la población infantil ocasionando un cuadro clínico grave, de evolución severa, así como un elevado número de muertes y ...
Bárbara Padilla-Docal, Rosa Ferro-Blanco, Alberto Juan Dorta-Contreras, Raisa Bu Coifiu-Fanego, Olga Susana De Paula-Almeida, René Martínez-Alderete   +5 more
doaj  

Is Early Complement Activation in Renal Transplantation Associated with Later Graft Outcome?

Kidney & Blood Pressure Research, 2018
Background/Aims: Complement activation is important in post-transplantation renal injury, but data on its role as predictor of transplant outcome/complications when assessed in donor kidneys are lacking.
Steffen Bobka, Nadja Ebert, Eloed Koertvely, Johannes Jacobi, Michael Wiesener, Maike Büttner-Herold, Kerstin Amann, Christoph Daniel   +7 more
doaj   +1 more source