Results 11 to 20 of about 26,400 (209)
Genetic mapping of complement system proteins for islet autoimmunity in children with high risk of T1D [PDF]
Communications BiologyRecent studies have reported the involvement of complement system proteins in the initiation and progression of islet autoimmunity (IA) in the study of Type 1 diabetes (T1D).
Xiaowei Hu +10 more
doaj +2 more sources
Complement C4, C4A and C4a – What they do and how they differ
Brain, Behavior, & Immunity - HealthMeike Heurich +2 more
doaj +5 more sources
Separation performance of PEG-linked calix[4]arene as stationary phase for capillary gas chromatography [PDF]
Química Nova, 2023 This work presented a new PEG modified calix[4]arene stationary phase (C4A-PEG-2PTSC) for gas chromatographic (GC) separations. The statically coated C4A-PEG-2PTSC column exhibited moderate polarity and column efficiency of 2224 plates m-1 determined by ...
Wei Zhang +8 more
doaj +1 more source
Pharmaceutics, 2023 Inhibition of ABC transporters is a promising approach to overcome multidrug resistance in cancer. Herein, we report the characterization of a potent ABCG2 inhibitor, namely, chromone 4a (C4a).
Glaucio Valdameri +18 more
doaj +1 more source
Research and Practice in Thrombosis and Haemostasis, 2021 Background Protease‐activated receptor (PAR) 1 and PAR4 are key thrombin signal mediators for human platelet activation and aggregation in response to vascular injury.
Xu Han +2 more
doaj +1 more source
Genome Biology, 2023 Background Increased expression of the complement component 4A (C4A) gene is associated with a greater lifetime risk of schizophrenia. In the brain, C4A is involved in synaptic pruning; yet, it remains unclear the extent to which upregulation of C4A ...
Leanna M. Hernandez +11 more
doaj +1 more source
Translational Psychiatry, 2022 We examined whether common variants from the extended major histocompatibility complex (xMHC) region contribute to the response to antipsychotic drugs (APDs) in patients with schizophrenia with persistent psychosis. Subjects participated in a prospective
Jiang Li +3 more
doaj +1 more source
npj Genomic Medicine, 2022 Copy number (CN) polymorphisms of complement C4 play distinct roles in many conditions, including immune-mediated diseases. We investigated the association of C4 CN with systemic sclerosis (SSc) risk.
Martin Kerick +24 more
doaj +1 more source
Trends in Ocean S‐Isotopes May Be Influenced by Major LIP Events
Geophysical Monograph Series, Page 341-376., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Ross. R. Large +5 more
wiley +1 more source
Increased activation product of complement 4 protein in plasma of individuals with schizophrenia
Translational Psychiatry, 2021 Structural variation in the complement 4 gene (C4) confers genetic risk for schizophrenia. The variation includes numbers of the increased C4A copy number, which predicts increased C4A mRNA expression.
Agnieszka Kalinowski +14 more
doaj +1 more source