Results 11 to 20 of about 9,499 (196)

C4d expression in focal segmental glomerulosclerosis

Nefrología (English Edition)
Background: There is a little information about of expression of C4d (complement fragment) in Focal segmental glomerulosclerosis (FSGS) subtypes. Our aim was to determine the expression of C4d in FSGS subtypes in percutaneous native renal biopsies in a ...
Venice Chávez Valencia, Victoriano Pérez-Vázquez, Anel Gómez García, Katya Vargas-Ortiz, Martha Arisbeth Villanueva Pérez, Marisol Godínez Rubí, Leonardo Pazarín Villaseñor, Sergio Gutiérrez Castellanos, Citlalli Orizaga de la Cruz   +8 more
doaj   +4 more sources

The Importance of C4d in Biopsies of Kidney Transplant Recipients [PDF]

Clinical and Developmental Immunology, 2013
Antibody-mediated rejection (AMR) is highly detrimental to the prolonged survival of transplanted kidneys. C4d has been regarded as a footprint of AMR tissue damage, and the introduction of C4d staining in daily clinical practice aroused an ever ...
Rosana Rosa Miranda Corrêa, Juliana Reis Machado, Marcos Vinícius da Silva, Fernanda Rodrigues Helmo, Camila Souza Oliveira Guimarães, Laura Penna Rocha, Ana Carolina Guimarães Faleiros, Marlene Antônia dos Reis   +7 more
doaj   +5 more sources

Pros and cons for C4d as a biomarker [PDF]

Kidney International, 2012
The introduction of C4d in daily clinical practice in the late nineties aroused an ever-increasing interest in the role of antibody-mediated mechanisms in allograft rejection.
Haas, M., Daha, Mohamed R., Colvin, R.B., Cohen, Danielle, Daha, M.R., Salmon, J.E., Sis, B., Bruijn, J.A., Drachenberg, C.B., Zhao, Ming-Hui, Cohen, D., Colvin, Robert B., Drachenberg, Cinthia B., Nickeleit, Volker, Bruijn, Jan A., Nickeleit, V., Bajema, Ingeborg M., Zhao, M.H., Sis, Banu, Bajema, I.M., Haas, Mark, Salmon, Jane E.   +21 more
core   +5 more sources

Glomerulitis and endothelial cell enlargement in c4d+ and c4d- acute rejections of renal transplant patients

Human Pathology, 2012
In acute rejection after renal transplant, glomerulitis is characterized by mononuclear cells in glomerular capillaries and endothelial cell enlargement.
Della Barbera M, Rigotti P, Valente M., Marino S, Furian L, AIELLO, Francesca Bianca, Cozzi E, Pierobon ES, Seveso M, Cardillo M   +9 more
core   +5 more sources

CERIF for datasets (C4D) [PDF]

, 2014
The overall aim of CERIF for Datasets (C4D) is to develop a framework for incorporating metadata into CERIF (the Common European Research Information Format) such that research organisations and researchers can better discover and make use of existing ...
Anna Clements, Kevin Ginty, Paul Cranner, Ginty, Kevin, Cranner, Paul, Scott Brander, McCutcheon, Valerie, Brander, Scott, Henderson, Ryan, Valerie McCutcheon, Clements, Anna, Ryan Henderson   +11 more
core   +3 more sources

Complement activation in astrocytomas: deposition of C4d and patient outcome [PDF]

BMC Cancer, 2012
Background C4d is a cleavage product of complement component C4 and is considered to serve as a marker for the site of complement activation. In this study C4d staining of grade I-IV astrocytic tumors was studied to explore if there is an association ...
Mäkelä Katri, Helén Pauli, Haapasalo Hannu, Paavonen Timo   +3 more
doaj   +3 more sources

Comparison of C4d Detection on Erythrocytes and PTC-C4d to Histological Signs of Antibody-Mediated Rejection in Kidney Transplantation [PDF]

American Journal of Transplantation, 2012
C4d on erythrocytes (EC4d), C4d peritubular capillary deposition (PTC-C4d) staining and histology were compared in a cross-sectional cohort of 146 renal allograft biopsies (132 patients).
Tabary, T, Noel, L H, Kisserli, A, Morelon, E, Rieu, P, Issa, N, Cohen, J H M, Réveil, B, Legendre, C, Thervet, E, McGregor, B, Haidar, Fadi, Toupance, O   +12 more
core   +4 more sources

Glomerular C4d Staining Does Not Exclude a C3 Glomerulopathy

Kidney International Reports, 2019
Introduction: C4d, an early product in the classical/lectin complement pathway has shown potential in the evaluation of C3 glomerulopathy where its absence would support an alternative pathway abnormality.
Geetika Singh, Shamresh Kumar Singh, Aasma Nalwa, Lavleen Singh, Immanuel Pradeep, Adarsh Barwad, Aditi Sinha, Pankaj Hari, Arvind Bagga, Soumita Bagchi, Sanjay Kumar Agarwal, Amit Kumar Dinda   +11 more
doaj   +2 more sources

Utility of C4D deposits in native renal diseases and relation with disease progression

Indian Journal of Health Sciences and Biomedical Research KLEU, 2019
INTRODUCTION: C4D is a well-known biomarker of complement cascade. The utility of C4D in identification of antibody-mediated rejection has been known since its incorporation in Banff classification in 2003.
Sucheta Yadav, Atin Singhai, Suresh Babu, Vijay Kumar Singh, Anupam Wakhlu, Satyendra Sonkar, Bhupendra Pal Singh, Chanchal Rana   +7 more
doaj   +2 more sources

Urinary C4d does not correlate with C4d-staining in peritubular capillaries but reflects nonspecific glomerular injury

Transplantation, 2008
BACKGROUND: C4d-staining in peritubular capillaries (PTC) in allograft biopsies is a hallmark of antibody-mediated rejection (AMR). This study investigated whether urinary C4d correlates with C4d-staining in PTC, allowing for a noninvasive screening ...
Mihatsch, M. J., Schaub, S., Dickenmann, M., Hönger, G., Mayr, M.   +4 more
core   +4 more sources