Results 71 to 80 of about 9,499 (196)

Estudio de las variables asociadas a la activación local del complemento en la nefropatía IgA idiopática

Nefrología, 2017
Objetivos: 1) Identificar las variables que se asocian con los niveles urinarios de MBL, C4d y C5b-9 en enfermos con nefropatía IgA idiopática. 2) Analizar si los niveles urinarios de MBL o C4d son útiles para identificar la presencia de depósitos ...
Alfons Segarra-Medrano, Clara Carnicer-Caceres, Naiara Valtierra-Carmeno, Irene Agraz-Pamplona, Natalia Ramos-Terrades, Elías Jatem Escalante, Elena Ostos-Roldan   +6 more
doaj   +1 more source

Animal models of idiopathic membranous nephropathy: Recent advances and future perspectives

Animal Models and Experimental Medicine, Volume 9, Issue 7, Page 1325-1337, July 2026.
This review focuses on the evolution of idiopathic membranous nephropathy (IMN) animal models from traditional approaches (Heymann nephritis, C‐BSA, APA) to antigen‐specific models (PLA2R, THSD7A), critically evaluating their advances and limitations in replicating human IMN pathology.
Qiuying Liu, Huixian Bian, Jianhua Liu, Lina Wu, Zhijie Zhang, Hongli Zhao, Xiaosong Qin   +6 more
wiley   +1 more source

Detection of T and B cells specific complement-fixing alloantibodies using flow cytometry: A diagnostic approach for a resource limited laboratory

Asian Journal of Transfusion Science, 2017
Background and Objectives: Various methods have been reported for the detection of antibodies in recipient sera, which can be human leukocyte antigens (HLAs) or non-HLA specific, complement- or noncomplement fixing, as well as donor T (HLA-Class-I) and ...
Dharmendra Jain, Pranav Dorwal, Amit Pande, Neetu Tyagi, Simmi Mehra, Vimarsh Raina   +5 more
doaj   +1 more source

Fourier Expansion‐Based Approach to the Parameter Space of Classical Systems

Annalen der Physik, Volume 538, Issue 7, July 2026.
ABSTRACT We propose a new approach to compute the classical metric tensor (CMT) and the Hannay curvature using Fourier series expansions in action‐angle variables. This approach circumvents the need for complex time‐domain integrals or the construction of generating functions, replacing them with algebraic combinations of Fourier coefficients. We prove
Marcos J. Hernández, Daniel Gutiérrez‐Ruiz, Diego Gonzalez, J. David Vergara   +3 more
wiley   +1 more source

Tissue and Serum Concentrations of Time‐Dependent Antibiotics in Infected Diabetic Foot Ulcers by Bolus or Continuous Administration: The Randomised DFIATIM Trial

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 5, July 2026.
ABSTRACT Aims The clinical effectiveness of antibiotic (ATB) therapy in patients with infected diabetic foot ulcers (iDFUs) depends on achieving sufficient ATB concentrations in both serum and peripheral tissues. This study evaluated the availability and bactericidal activity of the time‐dependent ATBs—ceftazidime (CTZ) and amoxicillin/clavulanate (AMC)
Radka Jarošíková, Dominika Sojáková, Simona Antalová, Petr Tůma, Jan Polák, Michal Dubský, Andrea Němcová, Veronika Wosková, Pavol Beca, Istvan Modos, Jan Mareš, Jakub Mrázek, Chahrazed Mekadim, Markéta Skružná, Vladimíra Fejfarová   +14 more
wiley   +1 more source

Complement Inhibition in the Clinic: Are We Doing Enough to Protect Patients From Infection?

European Journal of Immunology, Volume 56, Issue 7, July 2026.
Excessive complement activation is implicated in a broad range of diseases. Therapeutic approaches targeting the complement cascade, from pathway‐selective inhibition to terminal blockade, can effectively control disease activity. However, increasing degrees of complement inhibition are associated with a heightened susceptibility to bacterial, viral ...
Serena Bettoni, Ebba Qviberg, Edward Chaloner, Hayley Lavender, Maisem Laabei   +4 more
wiley   +1 more source

Measuring plasma C4D to monitor immune complexes in lupus nephritis

, 2019
Objective Because currently available assays that measure circulating immune complexes (ICx) are suboptimal, a novel assay was recently developed measuring C4d, a stable product of activation of the classical complement pathway.
Nilsson, Sara C., Nilsson, S.C., Blom, A.M., Van Kooten, Cees,, Teng, Yk Onno, Nilsson, Sara C.,, Kraaij, Tineke, Van Kooten, Cees, Kooten, C. van, Blom, Anna M., Okroj, M., Okrój, Marcin,, Okrój, Marcin, Teng, Y.K.O., Kraaij, T., Teng, Yk Onno,, Blom, Anna M.,, Lund University., Kraaij, Tineke,   +18 more
core   +1 more source

Digital pathology evaluation of complement C4d component deposition in the kidney allograft biopsies is a useful tool to improve reproducibility of the scoring

Diagnostic Pathology, 2011
Complement C4d component deposition in kidney allograft biopsies is an established marker of antibody-mediated rejection. In the Banff 07 classification of renal allograft pathology, semi-quantitative evaluation of the proportion of C4d-positive ...
Laurinavicius Arvydas, Brazdziute Ernesta   +1 more
doaj   +1 more source

Xenotransplantation Literature Update: January–June 2026

Xenotransplantation, Volume 33, Issue 4, July/August 2026.
ABSTRACT In the first half of 2026, xenotransplantation advanced through refinement rather than dramatic new clinical milestones. Clinical studies described graft physiology, immune infiltration, complement activation, coagulation incompatibility, and early function in living recipients, decedent models, and clinical islet xenotransplantation ...
Kasra Shirini, Joseph M. Ladowski, Niket Harsh, Raphael P. H. Meier   +3 more
wiley   +1 more source

The radio spectrum of the C4D radical

The Astrophysical Journal, 1988
Detection du radical C 4 D par decharge incandescente dans un melange de C 2 D 2 et d'H 2 .
D. R. Woodward, J. C. Pearson, C. A. Gottlieb, P. Thaddeus   +3 more
openaire   +1 more source