Results 51 to 60 of about 9,499 (196)

The Intensity of PLA2R and C4d Immunoexpression in Primary Membranous Nephropathy

Southern Clinics of Istanbul Eurasia, 2020
INTRODUCTION[|]Antibodies against the phospholipase A2 receptor (PLA2R) on podocyte membranes result in the formation of immune complexes that cause loss of function of the glomerular basement membrane in primary membranous nephropathy (PMN). It has also
Deniz Filinte, Hakkı Arıkan, Mehmet Koç, Handan Kaya, İshak Çetin Özener, Gamze Akbaş   +5 more
doaj   +1 more source

Cytokine‐Driven Hyperinflammation in Long COVID: Mechanisms, Biomarkers, Complement Dysregulation, and Emerging Immunotherapies—A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Long COVID, also known as post‐acute sequelae of SARS‐CoV‐2 infection (PASC), is a multisystem condition characterized by persistent symptoms that continue beyond the acute phase of infection. Growing evidence indicates that sustained immune dysregulation involving cytokine‐mediated inflammation, complement activation ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Study of the variables associated with local complement activation in IgA nephropathy

Nefrología (English Edition), 2017
Objectives: 1. To identify the variables that are associated with urinary levels of properdin, MBL, C4d, and C5b-9 in patients with idiopathic IgA nephropathy. 2. To analyse whether urinary levels of MBL and/or C4d are useful for identifying the presence
Alfons Segarra-Medrano, Clara Carnicer-Caceres, Naiara Valtierra-Carmeno, Irene Agraz-Pamplona, Natalia Ramos-Terrades, Elías Jatem Escalante, Elena Ostos-Roldan   +6 more
doaj   +1 more source

Serum S100P and C4d proteins as markers for active proliferative lupus nephritis in Egyptian patients with systemic lupus erythematosus

Український Журнал Нефрології та Діалізу, 2023
Lupus nephritis (LN), occurring in approximately 50% of individuals with systemic lupus erythematosus (SLE), significantly influences therapy and prognosis.
Mahmoud M. Elnokeety, Noha Khalil, Ahmed Fayed   +2 more
doaj   +1 more source

Clinical Heterogeneity of Refractory Ascites After Pediatric Liver Transplantation Modulates Allograft Rejection Risk

MedComm, Volume 7, Issue 9, September 2026.
Refractory ascites (RA) post‐pediatric LT is stratified into two subtypes: Type I (portal hypertension‐driven) and Type II (immune‐mediated). Type I is linked to low GRWR and hypersplenism, while Type II involves ABO incompatibility and early T‐cell activation (elevated sIL‐2R). Type II increases rejection risk (OR = 2.212).
Bingran Wang, Yunmu Gao, Jiaqi Song, Qi Pan, Aiwei Zhou, Hongyuan Liu, Wanglong Xiao, Zhicong Zhao, Taihua Yang, Chen Chen, Zhipeng Zong, Tao Zhou, Yi Luo, Yongbo Liu, Yuan Liu, Qiang Xia   +15 more
wiley   +1 more source

Analyses of the clinical and immunological characteristics of patients with lupus erythematosus

Indian Journal of Dermatology, 2022
Background: Lupus erythematosus (LE) is a broad-spectrum, heterogeneous disease. At one end of the spectrum is the cutaneous LE (CLE) without systemic involvement, and at the other end is the systemic LE (SLE) with multisystem involvement.
Min Deng, Ruifang Wu, Xingyu Zhou, Yuwen Su, Yaping Li   +4 more
doaj   +1 more source

Galactose‐Deficient Immunoglobulin A1 Predicts Immunoglobulin A Nephropathy Recurrence After Kidney Transplantation: A Single‐Center Retrospective Study

Organ Medicine, Volume 3, Issue 3, Page 139-147, September 2026.
Serum galactose‐deficient IgA1 levels at 3 and 6 months predicted recurrent IgA nephropathy after kidney transplantation. Recipients without recurrence showed a rapid decline in galactose‐deficient IgA1 after transplantation. Early identification of recurrence risk provided a potential window for targeted post‐transplant intervention.
Ronghai Deng, Wengen Chen, Xinhua Chang, Zehuan Chen, Qianyu Ye, Bowen Xu, Yifang Gao, Suxiong Deng, Xiaolin Yu, Changxi Wang, Xiangjun Liu   +10 more
wiley   +1 more source

İGA nefropatisinde mezengiyal ve arteriolar C4D depolanmasının prognoz ile ilişkisi

, 2022
İmmunglobulin A (IgA) nefropatisi, bütün dünyada en sık görülen primer glomerülonefrittir. IgA nefropatisi geniş bir klinik çeşitlilik göstermektedir. Asemptomatik hematüriden hızlı ilerleyici glomerülonefrite kadar farklı şiddetlerde klinikle prezente ...
YASEMİN AKTAŞ SAVRUN
core   +1 more source

Association of C4d with disease activity in anti-neutrophil cytoplasmic antibody-associated vasculitis: evidence for classical/lectin complement pathway activation

Arthritis Research & Therapy
Background We aimed to investigate the involvement of the classical/lectin complement pathway in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) by exploring the complement activation fragment C4d in association to AAV activity ...
Anna Juto, Myriam Martin, Albin Björk, Leonid Padyukov, Caroline Grönwall, Aleksandra Antovic, Annette Bruchfeld, Iva Gunnarsson, Anna M. Blom   +8 more
doaj   +1 more source

Case series: Kikuchi‐Fujimoto disease with diagnostic overlap

Rheumatology &Autoimmunity, Volume 6, Issue 3, Page 198-201, September 2026.
Kikuchi‐Fujimoto disease (KFD) is a rare, self‐limiting necrotizing lymphadenitis that poses significant diagnostic challenges due to its overlap with tuberculosis, systemic lupus erythematosus (SLE), and malignancy. We present four cases highlighting distinct diagnostic complexities: KFD mimicking tuberculosis with concomitant latent TB infection and ...
Ecem Kalemoglu, Ming Zheng, Danny Arias, Andreina M. Paulino, Aisha Niaz, James Devlin, Valentin Marian   +6 more
wiley   +1 more source