Results 61 to 70 of about 9,499 (196)

C4d Staining in the Diagnosis of C3 Glomerulopathy [PDF]

Journal of the American Society of Nephrology, 2015
In 2010 we suggested the term C3 glomerulopathy for glomerular disease in which there was isolated deposition of C3 in glomeruli in the absence of immunoglobulins and of components of the classic pathway of complement activation.[1][1] The presence of such isolated C3 implies that complement ...
openaire   +2 more sources

C4d/CD34 double-immunofluorescence staining of renal allograft biopsies for assessing peritubular capillary C4d positivity [PDF]

Modern Pathology, 2012
Immunofluorescence detection of the complement split product C4d along peritubular capillaries in renal allograft biopsies is the mainstay for the diagnosis of antibody-mediated rejection. The extent of peritubular capillary C4d positivity may have significant clinical ramifications; however, peritubular capillary density in the renal cortex is often ...
Kuang-Yu, Jen, Thuy B, Nguyen, Flavio G, Vincenti, Zoltan G, Laszik   +3 more
openaire   +2 more sources

Expresión de C4d en glomeruloesclerosis focal y segmentaria

Nefrología
Resumen: Antecedentes: Existe poca información acerca de la expresión del C4d (fragmento del complemento) en la glomeruloesclerosis focal y segmentaria (GEFS) y sus variantes.
Venice Chávez Valencia, Victoriano Pérez-Vázquez, Anel Gómez García, Katya Vargas-Ortiz, Martha Arisbeth Villanueva Pérez, Marisol Godínez Rubí, Leonardo Pazarín Villaseñor, Sergio Gutiérrez Castellanos, Citlalli Orizaga de la Cruz   +8 more
doaj   +1 more source

LATE RENAL GRAFT REJECTION: PATHOLOGY AND PROGNOSIS

Вестник трансплантологии и искусственных органов, 2014
Rejection has always been one of the most important cause of late renal graft dysfunction. Aim of the study was to analyze the prevalence of different clinico-pathological variants of rejection that cause late graft dysfunction, and evaluate their impact
E.S. Stolyarevich, L.Y. Artyukhina, I.G. Kim, L.G. Kurenkova, N.A. Tomilina   +4 more
doaj   +1 more source

Xenotransplantation of the Porcine Lung—From Immunological Barriers to Emerging Experimental Strategies

Xenotransplantation, Volume 33, Issue 5, September/October 2026.
ABSTRACT Lung transplantation is the only long‐lasting life‐saving treatment for patients with end‐stage pulmonary disease, but the ever‐growing shortage of suitable donor organs leads to high mortality rates of the afflicted patients. Xenotransplantation, the transplantation of organs across species, has emerged as a promising alternative. This review
Nathalie Roters, Niveditha Varma, Robert Ramm, Heiner Niemann, Patrick Zardo, Arjang Ruhparwar, Tobias Goecke   +6 more
wiley   +1 more source

Peritubular Capillary C4d Deposition in Chronic Allograft Dysfunction

, 2004
Peritubular capillary (PTC) C4d staining represents a marker for acute humoral rejection, however, the impact of positive staining on chronic allograft dysfunction has received little attention. Ninety-three renal allograft biopsies from 93 patients were
정현주, 김명수, 김세훈, 김순일, 김유선, 박기일   +5 more
core   +1 more source

Flow Cytometric Immune Profiling Enables Early Detection of Rejection in Islet Xenotransplantation

Xenotransplantation, Volume 33, Issue 5, September/October 2026.
ABSTRACT Background Islet xenotransplantation is a strategy for treatment of Type 1 Diabetes, but immune‐mediated rejection limits graft survival. This study investigated a strategy with flow cytometry–based immune monitoring to evaluate immunosuppressive therapy and provide indicators of graft rejection.
Huu Thanh Le, Erin Fuller, Lauen Joo, Evelyn J. Salvaris, Adwin Thomas, Yivee Chew, Min Hu, Francesco Ierino, Mark B. Nottle, Peter J. Cowan, Wayne J. Hawthorne   +10 more
wiley   +1 more source

Xstainer: A Novel Virtual Staining Tool Powered by Advanced Deep Learning Techniques

Advanced Intelligent Systems, Volume 8, Issue 8, August 2026.
Xstainer is a deep learning–based virtual staining framework that converts hematoxylin and eosin‐stained whole slide images into multiple histochemical stains, including Masson's trichrome, Periodic acid‐Schiff, Jones methenamine silver, and Toluidine blue.
Fatma Nur Kinali, Derya Demir, Kutsev B. Ozyoruk, Yasin Almalioglu, Emre C. Kose, Drew F. K. Williamson, Gurdeniz Serin, G. Evren Keles, Banu S. Kumbaraci, Ceren Utku, Uguray P. Hacisalihoglu, Ilknur Turkmen, Figen Ozturk, Kayhan Basak, Yavuz Nuri Ertas, Mehmet Turan   +15 more
wiley   +1 more source

Use of C4d as a diagnostic tool to classify membranoproliferative glomerulonephritis

Nefrología, 2017
Background: Membranoproliferative glomerulonephritis (MPGN type I, II and III) was reclassified in 2013 as MPGN and C3 glomerulopathy (C3G) based on the complement system activation mechanism.
Nirupama Gupta, Dara N. Wakefield, William L. Clapp, Eduardo H. Garin   +3 more
doaj   +3 more sources

C4d deposition in early renal allograft protocol biopsies.

, 2004
BACKGROUND: Deposition of the complement protein C4d in renal allograft biopsies obtained during graft dysfunction and rejection has been proposed to be a sensitive marker of antibody-mediated acute rejection.
Koo, DD, Cerundolo, L, Procter, J, Sutton, M, Friend, PJ, Fuggle, SV, Roberts, IS, Davies, DR, Friend, Peter, Quiroga, I, Barnardo, MC, Morris, PJ   +11 more
core   +1 more source