Results 101 to 110 of about 256,837 (255)

Unveiling a Near‐Total Rear Passivation for High Performance of Ultra‐Thin ACIGS

Advanced Science, EarlyView.
Ultra‐thin solar cells of (Ag,Cu)(In,Ga)Se2 (ACIGS) suffer from rear interface recombination, limiting their performance. To tackle it, a full coverage plasma enhanced chemically vapor‐deposited 8 nm porous SiOx passivation layer was implemented and evaluated. It is shown that a combination of the near‐complete passivation from silica and the formation
Xavier L. Pinheiro, António J. N. Oliveira, André F. Violas, Kevin Oliveira, Paulo A. Fernandes, Marika Edoff, Pedro M. P. Salomé, Jennifer P. Teixeira   +7 more
wiley   +1 more source

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

Advanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang, Shuiping Fu, Ye Xu, Jia Gao, Jiwei Ren, Xu Yang, Hesong Xu, Ge Sun, Yanjie Li, Yanlin Wang, Lu Jin, Peijuan Chen, Ying Xu, Jianhao Li, Hua Lin, Chujiao Hu, Kaixian Chen, Huan Xiong, Cheng Luo, Shijie Chen   +19 more
wiley   +1 more source

Effects of C5 supplementation on complement activity.

, 2019
Subjects’ sera were supplemented with purified C5 (commercial) to physiological concentration. C activity was assessed by the levels of sC5b-9 after activation with aggregated IgG (classical pathway, A) or Zymosan (alternative pathway, B).
Galia Stemer (6169478), Mona Shehadeh (6169469), Naomi Rahimi-Levene (4919683), Masad Barhoum (4676851), Ariel Aviv (6169475), Najib Dally (6169481), Lev Shvidel (6169472), Andrei Braester (4676842), Mona Yuklea (6169484), Regina Michelis (2889092), Tamar Tadmor (6169466)   +10 more
core   +1 more source

What have we learned from C5 palsy - A short communication [PDF]

, 2020
A study group on C5 palsy retrospectively reviewed 1001 cervical operations at their institutions in order to understand the incidence, prognosticators, pathogenesis, and outcome of C5 palsy after cervical operations. Three studies are summarized.
Anand, Sharath Kumar, Macki, Mohamed
core  

Bridging Horizontal to Vertical Radiative Cooling

Advanced Science, EarlyView.
Radiative cooling materials are mature but only work facing the sky, confining them to rooftops. Instead of developing new ones, this system bridges existing horizontal coolers to vertical windows using blades outside the glass. On an occupied urban building, windows stay up to 1.4°C below air temperature while preserving daylight, outward views, and ...
Xiangyu Meng, Gan Huang
wiley   +1 more source

Novel risk model for predicting incident atrial fibrillation in patients taking ω−3 fatty acid: sub-analysis of the STRENGTH randomized trial

American Journal of Preventive Cardiology
Background: Fish oils are associated with higher risk of incident atrial fibrillation (AF) in randomized trials, risk factors for this remain unknown.
Tom Kai Ming Wang, Stephen J. Nicholls, Clement Tan, Becky Yi-Wen Liao, Kathy Wolski, Julie St John, Steven E Nissen   +6 more
doaj   +1 more source

Ausschnittskarte zu Quadrant C5

, 2017
Karte 3.10 Ausschnittskarte zu Quadrant C5 (CC-BY TEXTELSEM 2015)
Fink, Christoph, Christoph Fink
core   +1 more source

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source