Results 111 to 120 of about 256,837 (255)
In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang +8 more
wiley +1 more source
Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan +13 more
wiley +1 more source
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie +7 more
wiley +1 more source
Engineered Transformer Base Editor with Enhanced Editing Efficiency
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen +5 more
wiley +1 more source
CIEX analysis of C5–antibody complexes.
When an antibody that recognizes a specific epitope in C5 is administered, two types of IC can form (A). A CIEX chromatography analysis was performed for the mixture of cynomolgus C5 and each anti-C5 antibody: 305LO1-SG407, 305LO1-SG419, 305LO5-SG115 ...
Yoshinao Ruike (6162533) +15 more
core +1 more source
Main Raman signals in RNA, related to helical backbone, ribofuranose ring, and nitrogenous bases, are affected by secondary structures that cause hyperchromic effects and significantly alter the Raman intensity. ABSTRACT Raman spectra of RNA nucleotide strands extracted from 20 SARS‐CoV‐2 strains, including the original Japanese isolate, Alpha, Beta ...
Giuseppe Pezzotti +11 more
wiley +1 more source
Enhanced Endophytic Colonization of Flavobacterium Promotes Plant Resistance to Fusarium Wilt
A natural microbial consortium employing a cross‐feeding strategy forms a stratified biofilm that promotes endophytic colonization of auxotrophic Flavobacterium. This enhanced colonization activates plant systemic resistance, effectively suppressing Fusarium wilt.
Xianfeng Ye +13 more
wiley +1 more source
Aryl‐Tethered Pendant Sterically Shielded Imidazoliums for Durable Anion Exchange Membranes
An aryl‐tethered, sterically shielded imidazolium architecture protects cationic sites from hydroxide attack while avoiding vulnerable benzylic cation–polymer linkages. Incorporated into poly(arylimidazolium) membranes, this dual‐protection design enhances alkaline and oxidative durability and supports prolonged alkaline water electrolysis, offering a ...
Jinggui Lei +8 more
wiley +1 more source

