C53 Interacting with UFM1-Protein Ligase 1 Regulates Microtubule Nucleation in Response to ER Stress [PDF]
ER distribution depends on microtubules, and ER homeostasis disturbance activates the unfolded protein response resulting in ER remodeling. CDK5RAP3 (C53) implicated in various signaling pathways interacts with UFM1-protein ligase 1 (UFL1), which ...
Anastasiya Klebanovych +9 more
doaj +5 more sources
A Novel C53/LZAP-interacting Protein Regulates Stability of C53/LZAP and DDRGK Domain-containing Protein 1 (DDRGK1) and Modulates NF-κB Signaling [PDF]
C53/LZAP (also named as Cdk5rap3) is a putative tumor suppressor that plays important roles in multiple cell signaling pathways, including DNA damage response and NF-kappaB signaling. Yet how its function is regulated remains largely unclear. Here we report the isolation and characterization of two novel C53/LZAP-interacting proteins, RCAD (Regulator ...
Jianchun, Wu +4 more
openaire +3 more sources
Forecasting realized volatility through financial turbulence and neural networks
This paper introduces and examines a novel realized volatility forecasting model that makes use of Long Short-Term Memory (LSTM) neural networks and the risk metric financial turbulence (FT).
Souto Hugo Gobato, Moradi Amir
doaj +1 more source
Eukaryotes have evolved various quality control mechanisms to promote proteostasis in the endoplasmic reticulum (ER). Selective removal of certain ER domains via autophagy (termed as ER-phagy) has emerged as a major quality control mechanism.
Madlen Stephani +28 more
doaj +1 more source
Value-at-risk predictive performance: a comparison between the CaViaR and GARCH models for the MILA and ASEAN-5 stock markets [PDF]
Purpose – This paper tests the accuracies of the models that predict the Value-at-Risk (VaR) for the Market Integrated Latin America (MILA) and Association of Southeast Asian Nations (ASEAN) emerging stock markets during crisis periods.
Ramona Serrano Bautista +1 more
doaj +1 more source
MCMC and GLMs for estimating regression parameters: Evidence from non-life Egyptian insurance sector [PDF]
Purpose – The purpose of this study is to estimate the linear regression parameters using two alternative techniques. First technique is to apply the generalized linear model (GLM) and the second technique is the Markov Chain Monte Carlo (MCMC) method ...
Mahmoud ELsayed, Amr Soliman
doaj +1 more source
[my]-Bis(diphenylphosphanyl)borato-[kappa]2P:P'-bis[dicarbonyl([eta]5-cyclopentadienyl)iron(II)] tetrachloridoferrate(III) chloroform solvate [PDF]
The title compound, [Fe2(C5H5)2(C24H22BP2)(CO)4][FeCl4]·CHCl3, is an oxidation product of CpFe(CO)2PPh2BH3. One pair of phenyl rings attached to the two different P atoms are almost parallel, as are the other pair [dihedral angles = 8.7 (5) and 8.9 (5)°].
Franz Dornhaus +5 more
core +2 more sources
The impact of COVID-19 outbreak on the Mauritian export trade: a disaggregated analysis [PDF]
Purpose – This study aims at evaluating the effect of the COVID-19 pandemic on the export trade system for Mauritius during the first half of 2020 (January 2020–June 2020).
Zameelah Khan Jaffur +5 more
doaj +1 more source
Deep Learning Predictive Models for Terminal Call Rate Prediction during the Warranty Period
Background: This paper addresses the problem of products’ terminal call rate (TCR) prediction during the warranty period. TCR refers to the information on the amount of funds to be reserved for product repairs during the warranty period.
Ferencek Aljaž +4 more
doaj +1 more source
When will European Muslim population be majority and in which country? [PDF]
Purpose – The purpose of this paper is to estimate the years the European Muslim population will be majority among 30 European countries. Design/methodology/approach – The methodology/approach is to forecast the population of 30 European countries with ...
Pierre Rostan, Alexandra Rostan
doaj +1 more source

