Results 31 to 40 of about 119,630 (242)
Frontiers in Chemistry, 2020 Gp36 is the virus envelope glycoproteins catalyzing the fusion of the feline immunodeficiency virus with the host cells. The peptide C8 is a tryptophan-rich peptide corresponding to the fragment 770W-I777 of gp36 exerting antiviral activity by binding ...
Daniele Di Marino +15 more
doaj +1 more source
Exploring the Preparation Dependence of Crystalline 2D-Extended Ultrathin C8-BTBT-C8 Films
ACS Applied Materials & Interfaces, 2022 Crystalline organic semiconducting thin films from the benchmark molecule C8-BTBT-C8 were obtained using physical vapor deposition and various solution-based methods. Utilizing atomic force microscopy and X-ray spectromicroscopy, we illustrate the influence of the underlying growth mechanism and determine the highly preparation-dependent orientation of
Tim Hawly +8 more
openaire +3 more sources
Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells
Advanced Science, EarlyView.Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li +8 more
wiley +1 more source
Persistence of the high solar potential in Africa in a changing climate
Environmental Research Letters, 2019 The African continent faces several challenges and threats: high vulnerability to climate change, the fastest population increase, the lowest degree of electrification and the need for an energy transition towards renewable energies.
Pedro M M Soares +2 more
doaj +1 more source
Advanced Science, EarlyView.This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao +13 more
wiley +1 more source
EBioMedicine, 2015 Background: The best investigational drug to treat cystic fibrosis (CF) patients with the most common CF-causing mutation (F508del) is VX-809 (lumacaftor) which recently succeeded in Phase III clinical trial in combination with ivacaftor.
Nikhil T. Awatade +8 more
doaj +1 more source
Scientific Reports, 2022 Poly(amic acid) (PAA) is prepared by the reaction of dianhydride 4,4′-biphthalic anhydride and diamine bis[4-(3-aminophenoxy)phenyl]sulfone in N,N’-dimethylacetamide.
Moon Young Choi +3 more
doaj +1 more source
Advanced Science, EarlyView.This study maps the spatiotemporal distribution of hydrophobic toxicants and endogenous metabolites in the developing placenta and fetus. By integrating mass spectrometry imaging with snRNA‐seq, we identify SR‐B1 as a key transporter driving early‐gestation xenobiotic transfer and reveal a critical exposure window associated with persistent fetal ...
Yixuan Huang +10 more
wiley +1 more source
Predicting stable binding modes from simulated dimers of the D76N mutant of β2-microglobulin
Computational and Structural Biotechnology Journal, 2021 The D76N mutant of the β2m protein is a biologically motivated model system to study protein aggregation. There is strong experimental evidence, supported by molecular simulations, that D76N populates a highly dynamic conformation (which we originally ...
Nuno F.B. Oliveira +5 more
doaj +1 more source
Advanced Science, EarlyView.Scheme illustrating the selective conversion of plastic waste to isomerized C4‐C12 products using RuSZ1 under different reaction conditions. ABSTRACT In recent years, catalytic hydrocracking has emerged as a promising waste‐to‐feedstock solution for processing plastic waste.
Xinbang Wu +8 more
wiley +1 more source