Results 51 to 60 of about 122,548 (238)

Measurements of Functional Responses in Human Primary Lung Cells as a Basis for Personalized Therapy for Cystic Fibrosis

EBioMedicine, 2015
Background: The best investigational drug to treat cystic fibrosis (CF) patients with the most common CF-causing mutation (F508del) is VX-809 (lumacaftor) which recently succeeded in Phase III clinical trial in combination with ivacaftor.
Nikhil T. Awatade, Inna Uliyakina, Carlos M. Farinha, Luka A. Clarke, Karina Mendes, Amparo Solé, Juan Pastor, Maria Margarida Ramos, Margarida D. Amaral   +8 more
doaj   +1 more source

A 3D‐Printed Blister Test Platform for Quantifying Biointerface Adhesion Mechanisms

Advanced Materials Interfaces, EarlyView.
A 3D‐printed blister platform enables energy‐resolved characterization of soft hydrogel–rigid interfaces. Integrating precision pressure control with hyperelastic modeling directly quantifies adhesion energy (G) and R‐curve toughening. Results reveal that modulating hydrogel concentration and surface roughness drives a tunable transition from cohesive ...
Yoontae Kim, Rahul Patil, Argyris K. Lazaris, Xinran Zhang, Stella Alimperti   +4 more
wiley   +1 more source

Exploring the Preparation Dependence of Crystalline 2D-Extended Ultrathin C8-BTBT-C8 Films

ACS Applied Materials & Interfaces, 2022
Crystalline organic semiconducting thin films from the benchmark molecule C8-BTBT-C8 were obtained using physical vapor deposition and various solution-based methods. Utilizing atomic force microscopy and X-ray spectromicroscopy, we illustrate the influence of the underlying growth mechanism and determine the highly preparation-dependent orientation of
Tim Hawly, Manuel Johnson, Andreas Späth, Hannah Nickles Jäkel, Mingjian Wu, Erdmann Spiecker, Benjamin Watts, Alexei Nefedov, Rainer H. Fink   +8 more
openaire   +3 more sources

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat. [PDF]

PLoS ONE, 2015
Focusing on the caprylic acid (C8:0), this study aimed at investigating the discrepancy between the formerly described beneficial effects of dietary medium chain fatty acids on body weight loss and the C8:0 newly reported effect on food intake via ...
Fanny Lemarié, Erwan Beauchamp, Stéphanie Dayot, Cécile Duby, Philippe Legrand, Vincent Rioux   +5 more
doaj   +1 more source

Climate Change Threatens Micronutrient Density of European Winter Wheat

Advanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao, Jennifer Michel, Eline Lorer, Markus Weinmann, Jacques Le Gouis, Claire Léon, Sibille Perrochon, David Alvarez, Vincent Leemans, Iñaki Balanzategui Guijarro, Jordi Moya Laraño, Sara Sánchez Moreno, Symanczik Sarah, Waibel Matthias, Hervé Vanderschuren, Cécile Thonar, Pierre Delaplace, Dominique Van Der Straeten   +17 more
wiley   +1 more source

Gravitational baryogenesis in f(T, Lm) gravity

Nuclear Physics B
The observed matter–antimatter asymmetry of the Universe remains a fundamental challenge in modern physics. In this work, we explore gravitational baryogenesis within the framework of f(T, Lm) gravity, where the gravitational Lagrangian depends on both ...
Daniel F P Cruz, David S. Pereira, Francisco S N Lobo   +2 more
doaj   +1 more source

HOXC8 (homeobox C8) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2015
Review on HOXC8 (homeobox C8), with data on DNA, on the protein encoded, and where the gene is implicated.
Huang, S, Li, Y
openaire   +2 more sources

Effect of Alkyl Chain Length on the Bandgap, Ferroelectric, and Photoelectric Properties of Lead‐Based Molecular Ferroelectrics

Advanced Science, EarlyView.
This study develops a novel 2D molecular ferroelectric [C6N2H18]PbI4 with polarization enhanced photovoltaics. It systematically investigates the effect of alkylamine spacer cation chain lengths on the band gap, ferroelectric, and photoelectric properties, offering new design strategies.
Ganghua Zhang, Jinrong Wen, Ping Chen, Zhibo Chen, Pingying Tang, Dezeng Li, Jingshan Hou, Yongzheng Fang   +7 more
wiley   +1 more source

Preliminary Examination of the Effects of Focused Ultrasound on Living Skin and Temperature at the Skin–Transducer Interface

Bioengineering
Transcranial Focused Ultrasound Stimulation (tFUS) is a new, rapidly growing field related to the study and treatment of brain circuits. Establishing safety cutoffs for focused ultrasound is crucial for non-ablative neurological ultrasound experiments ...
Andrew A. E. D. Bishay, Andrew J. Swenson, Norman M. Spivak, Samantha Schafer, Brendan P. Bych, Spencer D. Gilles, Christopher Dorobczynski, Alexander S. Korb, Mark E. Schafer, Taylor P. Kuhn, Martin M. Monti, Alexander Bystritsky   +11 more
doaj   +1 more source