Results 31 to 40 of about 122,548 (238)
Global offshore wind energy resources using the new ERA-5 reanalysis
Environmental Research Letters, 2020 A global quantitative characterization of offshore wind power density is presented over the economic exclusive zones (EEZs), at annual and seasonal scales, based on the recently released ECMWF ERA-5 reanalysis.
Pedro M M Soares +2 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
REDESIGNING PRESERVICE MATHEMATICS TEACHER’S LESSON PLAN BY USING PRODUCTIVE PEDAGOGIES FRAMEWORK [PDF]
Journal of Engineering Science and Technology, 2018 This paper aims at describing an innovative course which encourages presevice teachers to reflect on their quality of instructional plan as well as its implementation within a field teaching experience and to redesign lesson plan based on the four ...
ABADI ABADI, ROOSELYNA EKAWATI
doaj
Scientifica, 2016 Background. Surgery for GI dysmotility is limited to those with severe refractory disease. Though effective, use of serotonergic promotility drugs has been restricted in Canada due to adverse events.
Biniam Kidane +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Life Situation of Polish Seniors – Their Subjective Assessment
Folia Oeconomica StetinensiaSeniors wield influence across a spectrum of social spheres. Understanding their attitudes, needs, challenges, and expectations emerges as imperative for shaping effective social policies and social inclusion. Their significant heterogeneity necessitates
Przybysz Klaudia, Stanimir Agnieszka
doaj +1 more source
Gravitational baryogenesis beyond the spectator approximation
Physics Letters BThe standard gravitational-baryogenesis operator λ ∇μR Jμ, with λ≡ϵ/M*2, is usually treated as a spectator interaction that generates an effective chemical potential in a prescribed background.
David S. Pereira +2 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Traumatic spinal cord injury (TSCI) caused by sharp‐force penetration is exceptionally rare, and the use of high‐dose methylprednisolone (MP) remains highly controversial, especially beyond the conventional 8‐h treatment window. This case report describes a 30‐year‐old male with acute incomplete TSCI following a knife stab wound to the right ...
Honghong Wang +5 more
wiley +1 more source
Baryon asymmetry from higher-order matter contributions in gravity
Physics Letters BWe investigate the observed asymmetry between matter and antimatter by incorporating higher-order matter contributions in gravity, specifically analyzing gravitational baryogenesis within the framework of f(R,T2) gravity, where R is the Ricci scalar and ...
David S. Pereira +2 more
doaj +1 more source