Results 91 to 100 of about 2,529,224 (293)

CA-125 and Ceruloplasmin Levels in Ovarian Cancer Patients

open access: yesÇukurova Üniversitesi Tıp Fakültesi Dergisi, 2015
Purpose: The initial stage of proliferation of epithelial ovarian carcinoma (EOCa) is usually asymptomatic. Due to the lack of sensitive and reliable markers in majority of patients the disease is widespread at the time of diagnosis.
Mangala Hegde   +4 more
doaj  

The diagnosis and pathological value of combined detection of HE4 and CA125 for patients with ovarian cancer

open access: yesOpen Medicine, 2016
To evaluate the value of individual and combined measurement of human epididymis protein 4 (HE4) and cancer antigen 125 (CA-125) in the diagnosis of ovarian cancer.
Zheng Li-e, Qu Jun-ying, He Fei
doaj   +1 more source

Value of CA-125 Glycoprotein in Predicting Acute Appendicitis; a Diagnostic Accuracy Study

open access: yesArchives of Academic Emergency Medicine, 2019
Introduction: Carcinogen antigen 125 (CA-125) is a glycoprotein antigen, which has shown potentials in predicting peritoneal inflammation. The aim of this study is to determine the value of CA-125 in predicting acute appendicitis (AA).
Mahboub Pouraghaghaei   +6 more
doaj   +1 more source

Purification and Characterization of the CA 125 Tumor-Associated Antigen from Human Ascites

open access: yesTumor Biology, 1993
CA 125 is an antigenic determinant associated with epithelial ovarian carcinomas, which is recognized by a monoclonal antibody, OC 125. The biochemical structure, the immunological characteristics and the physiological function of CA 125 are unknown, principally because the molecule expressing it has not been purified to homogeneity.
M T, de los Frailes   +4 more
openaire   +2 more sources

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

open access: yesAdvanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen   +7 more
wiley   +1 more source

Physiologic variations of serum tumor markers in gynecological malignancies during pregnancy: a systematic review

open access: yesBMC Medicine, 2012
Background Recent insights provide support for the treatment of cancer during pregnancy, a coincidence that poses both mother and fetus at risk. Our aim was to critically review studies on the physiologic variations during pregnancy, the most common ...
Han Sileny N   +5 more
doaj   +1 more source

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma

open access: yesAdvanced Science, EarlyView.
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu   +13 more
wiley   +1 more source

[CA-125 antigen in patients with cancer of the uterine body].

open access: yesWiadomosci lekarskie (Warsaw, Poland : 1960), 1991
In 72 patients with malignant neoplasms of uterine body the serum concentration was determined of CA 125 antigen. In 38 cases serum samples were taken before oncological treatment and in 34 cases after the first stage of treatment. It was found that CA 125 concentration was significantly higher in patients before the treatment, with higher values in ...
M, Gisterek   +2 more
openaire   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao   +2 more
wiley   +1 more source

The Role of CA‐125 in the Management of Ovarian Cancer: A Systematic Review

open access: yesCancer Reports
Background Ovarian cancer is frequently occurring and fatal for women. CA‐125 is important in the screening, diagnosis, and treatment of ovarian cancer.
Zohre Momenimovahed   +3 more
doaj   +1 more source

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