A quarter of a century since its discovery, circulating CA125 antigen is recommended for clinical use in the USA for ovarian cancer screening of high-risk women with ovaries, despite its limited sensitivity and specificity. Recent findings suggest that CA125 might also serve as a predictive marker for pre-invasive ovarian carcinoma. Methods to quantify
Nathalie, Scholler, Nicole, Urban
openaire +2 more sources
CA125 Immune Complexes in Ovarian Cancer Patients with Low CA125 Concentrations [PDF]
BACKGROUND About 20% of women with ovarian cancer have low concentrations of serum cancer antigen 125 (CA125), and this important tumor marker cannot be used to monitor their disease. The measured concentration for mucin 1 (MUC1), or CA15-3, another tumor marker, can be lowered in breast and ovarian cancer patients ...
Cramer, Daniel +7 more
openaire +3 more sources
Objective: This study was done to evaluate and compare the use of RMI score & IOTA Simple Rule which has been routinely used in Hasan Sadikin Hospital to predict ovarian malignancy in 2017-2018 Method: This is a comparative study that collects data ...
Huda Toriq +2 more
doaj +1 more source
Expression and clinical significance of CA125, CA153 and CEA in nipple discharge of breast cancer patients [PDF]
Background: It is an important clinical means to identify benign and malignant breast diseases caused by nipple discharge through the detection and analysis of components in nipple discharge.
Geng Jun +5 more
doaj +1 more source
HE4 in the differential diagnosis of ovarian masses [PDF]
Ovarian masses, a common finding among pre- and post-menopausal women, can be benign or malignant. Ovarian cancer is the leading cause of death from gynecologic malignancy among women living in industrialized countries.
ANASTASI, Emanuela +5 more
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Alternative antibody for the detection of CA125 antigen: a European multicenter study for the evaluation of the analytical and clinical performance of the Access (R) OV Monitor assay on the UniCel (R) Dxl 800 Immunoassay System [PDF]
Background: Cancer antigen CA125 is known as a valuable marker for the management of ovarian cancer. Methods: The analytical and clinical performance of the Access OV Monitor Immunoassay System (Beckman Coulter) was evaluated at five different European ...
Anonymous +12 more
core +3 more sources
Evaluation of the Calculated Risk of Malignancy Index as a Predictor of the Nature of Adnexal Masses [PDF]
Background: Adnexal masses are common presentation among gynecological practice. Differentiation of benign than malignant lesions is of utmost importance for treatment plan. The gold standard other than histopathology did not determined yet.
Taher Mohamed Mostafa +2 more
doaj +1 more source
Graphene oxide-Au nano particle coated quartz crystal microbalance biosensor for the real time analysis of carcinoembryonic antigen [PDF]
A label-free quartz crystal microbalance (QCM) biosensor was developed for the selective and real-time estimation of carcinoembryonic antigen (CEA) through the present study.
Fu, Chen +5 more
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Qiang Yi, Yu Ran, Cong Li Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Cong Li No.
Yi Q, Ran Y, Li C
doaj
Using serum CA125 to assess the activity of potential cytostatic agents in ovarian cancer [PDF]
Objective: New strategies are required to rapidly identify novel cytostatic agents before embarking on large randomized trials. This study investigates whether a change in rate of rise (slope) of serum CA125 from before to after starting a novel agent ...
Ann Petruckevitch +21 more
core +1 more source

