Results 71 to 80 of about 42,942 (233)

Systematic Analysis of Circulating Soluble Angiogenesis-Associated Proteins in ICON7 Identifies Tie2 as a Biomarker of Vascular Progression on Bevacizumab [PDF]

, 2016
background: There is a critical need for predictive/resistance biomarkers for VEGF inhibitors to optimise their use. methods: Blood samples were collected during and following treatment and, where appropriate, upon progression from ovarian cancer ...
A Backen, A Floquet, Alison Backen, AM Oza, Andrew Clamp, Andrew Renehan, BJ Monk, C Aghajanian, C Daly, Carlo Berzuini, Caroline Dive, Cong Zhou, D Gerald, D Jelovac, E Pujade-Lauraine, Eric Pujade-Lauraine, GC Jayson, GJ Rustin, Gordon C Jayson, Gunnar B Kristensen, I Vergote, P Therasse, RA Burger, Richard Kaplan, Rosamonde E Banks, RS Herbst, S Epskamp, S Pignata, Stefan J Scherer, TJ Perren, TT Batchelor   +30 more
core   +3 more sources

Specific antitumor activity of anti-CA125 CAR-T lymphocytes against CA125-positive and CA125-negative cells

Sechenov Medical Journal
Aim. To evaluate the antitumor efficacy of our developed drug based on cytotoxic T lymphocytes genetically modified with a chimeric antigen receptor (CAR) specific to the CA125 antigen in relation to both CA125-positive and CA125negative cell cultures.Materials and methods.
T. M. Kulinich, Ya. Yu. Kiseleva, A. M. Shishkin, E. A. Kudinova, O. B. Knyazeva, R. Ranjit, V. K. Bozhenko, V. A. Solodky   +7 more
openaire   +2 more sources

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma

International Journal of Cancer, EarlyView.
What's New? Ovarian clear cell carcinoma is highly associated with hypoxia. Hypoxia‐inducible factor 2A (HIF2A) is a key regulator of hypoxic responses, but its role in ovarian clear cell carcinoma remains unclear. This study demonstrated the unfavorable prognostic significance of HIF2A expression in ovarian clear cell carcinoma.
Mengxin Jiang, Ken Yamaguchi, Kohei Hamada, Yuko Hosoe, Yuka Mise, Sachiko Kitamura, Zhihong Liu, Hairong Wei, Zhenhai Gao, Mana Taki, Koji Yamanoi, Ryusuke Murakami, Rin Mizuno, Taito Miyamoto, Junzo Hamanishi, Masaki Mandai   +15 more
wiley   +1 more source

Biochemical markers in cancer of the ovary : a review [PDF]

, 1990
The ideal tumour marker would be one which is detectable before obvious clinical involvement. A number of biochemical markers have been used to diagnose carcinoma of the ovary.
Cauchi, Maurice N.
core  

Role of galectin-3 combined with multi-detector contrast enhanced computed tomography in predicting disease recurrence in patients with ovarian cancer [PDF]

, 2017
Galectin-3 (Gal-3) is an endogenous β-galactoside-binding lectin, playing an important role in the pathogenesis of multiple malignancies. Aim of the study was to evaluate in a group of patients treated for ovarian cancer (EOC), the role of Gal-3 ...
ANASTASI, Emanuela, ANGELONI, Antonio, BALLESIO, Laura, CATALANO, Carlo, GIGLI, SILVIA, Granato, T, MANGANARO, Lucia, PORPORA, Maria Grazia, SANTULLI, Maria, TARTAGLIONE, SARA   +9 more
core   +1 more source

Exploring the impact of microbial dysbiosis on ovarian cancer and the therapeutic potential of probiotics

VIEW, EarlyView.
Ovarian cancer has been linked to the microbiome as a potential environmental contributor, but how this association relates to tumor progression remains unclear. By comparing tumor and nontumor tissues, we identified a severity‐associated microbial and metabolic signature and showed that probiotics can partially restore immune balance and slow tumor ...
Chanyuan Li, Nalan Tu, Xin Ning, Yunyan Cong, Fei Wu, Xiuli Zhang, Runrong Li, Yue Xu, Binqiao Wang, Liqin Jin, Yuanming Shen, Jihong Liu   +11 more
wiley   +1 more source

Surveillance After Pelvic Exenteration: A Systematic Review of Oncological and Functional Follow‐Up

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Surveillance following cancer surgery with curative intent serves the purpose of permitting early detection of recurrent disease in addition to monitoring and management of post‐resection functional sequelae. Although recommendations exist for most primary cancers, in the context of radical or re‐operative surgery such as pelvic ...
Adrian Hang Yue Siu, Konrad Joseph, Daniel Steffens, Sharon Carey, Michael Solomon, Cherry Koh   +5 more
wiley   +1 more source

Prognostic value of CA125 in advanced heart failure patients [PDF]

, 2009
INTRODUCTION: Serum levels of CA125 are often high in advanced heart failure (AHF) patients. AIM: To determine the predictive value of CA125 in forecasting the occurrence of death or cardiac transplantation in an AHF population.
Coelho, L, Costa, S, Franco, F, Monteiro, P, Monteiro, S, Oliveira, L, Providência, LA, Vieira, H   +7 more
core  

Amniotic fluid embolism pathophysiology suggests the new diagnostic armamentarium: β-tryptase and complement fractions C3-C4 are the indispensable working tools [PDF]

, 2015
Amniotic fluid embolism (AFE) is an uncommon obstetric condition involving pregnant women during labor or in the initial stages after delivery. Its incidence is estimated to be around 5.5 cases per 100,000 deliveries.
Busardo', FRANCESCO PAOLO, Fineschi, Vittorio, Frati, Paola, Zaami, Simona   +3 more
core   +2 more sources