Results 121 to 130 of about 5,917,592 (236)

Pharmacogenomic profiling of the efficacy of gemcitabine monotherapy in metastatic pancreatic cancer: Subgroup analysis of the GENESECT study

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3397-3406, October 2026.
Aim In the GENESECT study, no significant gemcitabine (GEM) metabolism‐related germline genetic polymorphisms (GPs) were identified because approximately 70% of patients received combination therapy with nab‐paclitaxel, which has metabolic pathways different from GEM.
Takashi Yokokawa, Daiki Tsuji, Masahiro Hatori, Kazuyoshi Kawakami, Masahiko Nakao, Takuya Yano, Yuichiro Arakawa, Keisuke Matsuo, Yasukata Ohashi, Masato Ozaka, Naoki Sasahira, Yasuhiko Sakata, Yuki Kogure, Shinya Tamaki, Atsushi Wada, Yusuke Taki, Wataru Suzuki, Kazuo Kobayashi, Hiroshi Ishii, Kunihiko Itoh, Masakazu Yamaguchi, Kenichi Suzuki   +21 more
wiley   +1 more source

Prognostic Value of Perioperative Inflammatory–Immune–Nutritional Indicators in Advanced Gallbladder Cancer

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Objective To explore the perioperative changes in inflammatory–immune–nutritional indicators in patients with advanced gallbladder cancer (GBC), defined as American Joint Committee on Cancer (AJCC) Stage III–IV, and to assess whether individual indicators provide incremental prognostic information beyond conventional clinicopathological ...
Rongxuan Li, Bingchen Wang, Xiao Chen, Dayong Cao, Jianguo Zhou   +4 more
wiley   +1 more source

Chronic Granulomatous Peritonitis From Recurrent Bilateral Ovarian Mature Cystic Teratomas Masquerade as Peritoneal Carcinomatosis

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Although rare, ruptured mature cystic teratoma (MCT) can cause chronic granulomatous peritonitis that mimics peritoneal carcinomatosis. In patients with a history of cystectomy for MCT, careful clinicoradiologic and histopathologic correlation is essential to avoid misdiagnosis and unnecessary aggressive treatment.
Zohre Sadeghian, Joel Cardenas, Kirill Lyapichev, Albert Parlade, Elvia Goez‐Gutierrez, Amir Behdad, Esther Yoon   +6 more
wiley   +1 more source

Extraordinary elevated CA19-9 in patient with common bile duct stones and cholangitis Case report

مجله دانشگاه علوم پزشکی بیرجند, 2012
Serum Carbohydrate Antigen, CA19-9, is a carbohydrate antigen whose usage -as a tumor marker- in pancreatic and bile ducts malignancies is commonly increasing.
Ali Mokhtarifar, Tahere Fakharian, Elham Mokhtari   +2 more
doaj  

Mixed Neuroendocrine—Non‐Neuroendocrine Neoplasm (MiNEN) of the Gallbladder. A Case Report From a Low‐Resource Setting

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Mixed neuroendocrine–non‐neuroendocrine neoplasms (MiNENs) of the gallbladder are exceedingly rare entities. We report a case of a 35‐year‐old female with a palpable right hypochondrial mass. Imaging demonstrated a large polypoid gallbladder lesion with periportal lymphadenopathy. The patient underwent open cholecystectomy with lymphadenectomy.
Muhammad Farhan, Muhammad Imran, Beenish Sabir, Khalil Ahmad, Farheen Khan, Shahid Hussain, Zohaib Ahmed, Muhammad Asim, Iqra Mehmood, Rahmat Gul Omarzai   +9 more
wiley   +1 more source

Lateraalivirtausmääritys syöpämerkkiaineelle CA19-9 munasarjasyövän diagnostiikkaan

Munasarjasyöpä on gynekologisista syövistä kolmanneksi yleisin ja toiseksi eniten kuolemaan johtava syöpä. Munasarjasyövän diagnoosi viivästyy usein epämääräisten oireiden ja riittämättömien biomerkkiaineiden takia.
Leppä, Kaisa
core  

CLDN18.2 in pancreatic ductal adenocarcinoma: Biomarker assessment, spatial heterogeneity and therapeutic modality selection

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review presents a framework for selecting Claudin 18.2 (CLDN18.2)‐directed treatment modalities in pancreatic ductal adenocarcinoma according to tumour antigen coverage and spatial distribution. Representative assessment at baseline and reassessment after progression can guide treatment adaptation over time.
Ruyu Tan, Zhexin Zhang, Jiaxin Wang, Roland Andersson, Daniel Ansari, Jinfei Chen   +5 more
wiley   +1 more source

Impact of Liver Metastases on Outcomes With Chemotherapy or Immune Checkpoint Inhibitors in Pancreatic Cancer

Immunity, Inflammation and Disease, Volume 14, Issue 10, October 2026.
ABSTRACT Background Pancreatic cancer (PC) is on the rise worldwide, with significant improvements in survival rates still awaited. Most patients are diagnosed at an advanced stage, often with liver metastases (LM), associated with poor prognosis and immunosuppression.
Laura K. Kjær, Susann Theile, Kasper Madsen, Julia S. Johansen, Morten Orebo Holmström, Mads Hald Andersen, Inna M. Chen   +6 more
wiley   +1 more source

Long‐Term Survival Following Nivolumab Treatment in Pulmonary Tumour Thrombotic Microangiopathy Associated With Cancer of Unknown Primary: A Case Report

Respirology Case Reports, Volume 14, Issue 10, October 2026.
Pulmonary tumour thrombotic microangiopathy (PTTM) is a rapidly fatal condition that is rarely diagnosed during life. Early clinical recognition and prompt nivolumab treatment resulted in long‐term survival in a patient with cancer of unknown primary‐associated PTTM.
Kosuke Fujishima, Jun Osugi, Satoshi Noma, Mitsunori Higuchi, Hiroyuki Suzuki   +4 more
wiley   +1 more source

Comparative Study of Elevated CA19-9 Levels in Non-Gastrointestinal Tumors Patients: Evaluation of Different Immunoassay Methods and Analysis of Potential Interfering Factors

Biomedicines
Objectives: CA19-9 elevation in non-gastrointestinal tumor patients may be influenced by various non-tumor factors, which poses challenges for clinical diagnosis.
Yangyang Liu, Wenxuan Li, Shaoxi Tang, Ruihao Wu, Yumin Wang, Fanggui Shao   +5 more
doaj   +1 more source