Results 91 to 100 of about 9,180 (218)

A Modified Method Incorporating Multiplex PCR Reveals Fusobacterium Prevalence in Southern Chinese Population and Its Correlations in Cancers

Microbial Biotechnology, Volume 18, Issue 12, December 2025.
By large‐scale comparative genomics, we identified species and subspecies‐specific genetic markers in Fusobacterium, and developed a high‐precision multiplex PCR assay that allows concurrent identification of five species of Fusobacterium (F. nucleatum, F. mortiferum, F. ulcerans, F. varium and F. necrophorum) and four subspecies of F.
Tingting Shen, Jiarui Liang, Xuyu Li, Xiaoxie Xu, Liqiong Li, Yinjuan Xu, Shanshui Zeng, Bingyu Li, Hui Li, Mengyao Hu, Lang Zhou, Siqi Yan, Ya Zhang, Ziwei Zhou, Huaaishi Liang, Shulei Chen, Zhikun Liang, Congrong Wang, Hongwei Zhou, Dongxin Zhang   +19 more
wiley   +1 more source

Ex-ante Assessment of Drought Tolerant Bean Technology. A case study in the series: Economic Foresight for Understanding the Role of Investments in Agriculture for the Global Food System [PDF]

, 2017
In this paper we apply an integrated biophysical and economic foresight modeling approach to investigate the impacts of climate change on the global agricultural economy, and the role that new crop technology could play in mitigating these impacts.
International Center for Tropical Agriculture
core  

Targeting ARPC1B + Cancer Stem Cells to Sensitise Pancreatic Cancer to Gemcitabine Treatment

Cell Proliferation, Volume 58, Issue 12, December 2025.
ARPC1B+ cancer stem cells (CSCs) in pancreatic cancer are identified as a subpopulation resistant to gemcitabine. In our study, drug repositioning, molecular docking, and surface plasmon resonance (SPR) technique jointly revealed that CK‐636 can directly target ARPC1B protein with high affinity. In vitro cytotoxicity, ex vivo organoid cultures, in vivo
Yang Wu, Jianpeng Zhang, Weixiong Zhu, Xinrui Zhu, Yi Liu, Xin Wang, Tianyu Zhao, Chun Zhang, Zili Zhang, Wenjie Shi, Run Shi, Zhaokai Zhou, Shaohui Xu   +12 more
wiley   +1 more source

Development and Validation of a New Prediction Criteria for Neoadjuvant Chemotherapy Response in Locally Advanced Gastric Cancer Based on Ferroptosis‐Related Biomarkers

Journal of Gastroenterology and Hepatology, Volume 40, Issue 12, Page 2913-2924, December 2025.
ABSTRACT Background The efficacy of neoadjuvant chemotherapy (NAC) combined with surgery and postoperative adjuvant chemotherapy in improving the prognosis of locally advanced gastric cancer (LAGC) has been confirmed. Nevertheless, there is still no effective tool to predict the response to NAC in gastric cancer patients.
Minxuan Shen, Qinbo Cai, Rongchang Wang, Feiran Zhang, Huanjie Chen, Xiaoqun Wang, Rongman Xie, Jie Zhang, Baoyi Liu, Yulong He, Xun Hou, Dongjie Yang   +11 more
wiley   +1 more source

血清CA125和CA199检测对卵巢癌诊断应用价值的探讨

Zhongguo shiyan zhenduanxue, 2014
目的通过测定血清中肿瘤标志物CA125和CA199水平,探讨其对卵巢癌诊断的应用价值。方法 2011年1月至2012年10月确诊的卵巢癌患者61例,卵巢良性疾病患者68例,健康对照者50例,测定血清中CA125和CA199水平。结果卵巢癌组血清CA125和CA199水平均明显高于卵巢良性疾病组和健康对照组,差异有统计学意义（P0.05）;CA125和CA199联合检测的敏感性明显高于CA125和CA199单独检测 ...
王珂, 汪丽, 程苏晶, 冷维春
doaj  

Serum and ascites tumor markers in the diagnostic and prognostic prediction for appendiceal pseudomyxoma peritonei

BMC Cancer, 2023
Background To investigate the expression of carcinoembryonic antigen (CEA), cancer antigen 199 (CA199) and CA125 in serum and ascites of appendiceal pseudomyxoma peritonei (PMP) patients relative to their diagnostic and predictive value.
Bing Wang, Ruiqing Ma, Benqiang Rao, Hongbin Xu   +3 more
doaj   +1 more source

Early Pancreatic Cancer Diagnosis via Ultrasensitive THz Toroidal Metasensing

Advanced Photonics Research, Volume 6, Issue 11, November 2025.
This study introduces a revolutionary terahertz metasurface biosensor using gold nanoparticles to boost sensitivity. It achieves precise detection of ultra‐low biomarker concentrations (1–1000 pg mL−1) with a 97.6 GHz/RIU sensitivity through optimized antibody binding.
Peng Wang, Mingming Jiang, Qingzhe Jia, Zhaofu Ma, Chenjie Liu, Hui Dai, Yanan Jiao, Liangli Cao, Jing Lou   +8 more
wiley   +1 more source

Serum IL-17A as a Diagnostic and Prognostic Biomarker in Colorectal Cancer: Development and Validation of a Multi-Indicator Model [PDF]

Objective: Colorectal cancer ranks as the third most prevalent malignancy globally. To address the limited sensitivity of conventional biomarkers, this study evaluated the clinical utility of preoperative serum interleukin-17A (IL-17A) in CRC diagnosis ...
Jia, Houjun, Li, Jiancheng
core   +2 more sources

Management of Primary Hepatic Carcinoma by Traditional Chinese Medicine [PDF]

, 2018
Primary hepatic carcinoma is one of the types with high incidence of cancer. It has the characteristics of hidden disease, long incubation period, rapid development and easy metastasis, and the prognosis is poor, which seriously affects the quality of ...
Cheng Jinlai, Leng Jing, Xia Meng
core   +1 more source

Analysis of Risk Factors for Leukoaraiosis: A Multicenter Retrospective Study

Brain and Behavior, Volume 15, Issue 11, November 2025.
This study was to analyze the risk factors clinically associated with the development of leukoaraiosis, and to explore clinical biomarkers that may predict leukoaraiosis. The results demonstrate that age, systolic blood pressure, ischemic stroke, and FT4 level serving as factors affecting the development of leukoaraiosis.
Lingqi Sun, Wang Guo, Yi Li, Li Fang, Ji Ma, Xiangdong Tang   +5 more
wiley   +1 more source