Results 81 to 90 of about 7,271 (215)
Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.Immune checkpoint inhibitors cause elevated cardiac injuries in humans and mice. ICIs cause myocyte pyroptosis and cardiotoxicity, not via the adaptive immune system BACH2 ameliorates ICIs‐induced pyroptosis through transcriptionally promoting GRSF1. Lipoic acid, as a transcriptional inducer of BACH2, suppresses ICIs‐induced cardiotoxicity.
Mengying Cao +9 more
wiley +1 more source
Journal of Clinical Laboratory Analysis, Volume 40, Issue 4, February 2026.This study developed and validated a clinical prediction model to differentiate non‐small cell lung cancer (NSCLC) from benign pulmonary diseases using clinical features, laboratory biomarkers, and CT features. The model achieved an AUC‐ROC of 0.95 in the training set and 0.82 in the validation set, demonstrating reliable diagnostic performance and ...
Jie Zhang +5 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 1, January 2026.ABSTRACT Background Colorectal cancer (CRC) with synchronous peritoneal metastasis (SPM) presents poor prognosis and complex treatment challenges. This study aimed to identify independent prognostic factors and develop nomogram‐based prediction models for overall survival (OS) and progression‐free survival (PFS) in CRC patients with SPM (CRC‐SPM ...
Xiaoxu Ge +11 more
wiley +1 more source
Integrated Microfluidic Chip for Neutrophil Extracellular Vesicle Analysis and Gastric Cancer Diagnosis [PDF]
Neutrophil-derived extracellular vesicles (NEVs) are critically involved in disease progression and are considered potential biomarkers. However, the tedious processes of NEV separation and detection restrain their use. Herein, we presented an integrated
Feng, Chunlai +8 more
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Management of Primary Hepatic Carcinoma by Traditional Chinese Medicine [PDF]
, 2018 Primary hepatic carcinoma is one of the types with high incidence of cancer. It has the characteristics of hidden disease, long incubation period, rapid development and easy metastasis, and the prognosis is poor, which seriously affects the quality of ...
Cheng Jinlai, Leng Jing, Xia Meng
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Zhongguo shiyan zhenduanxue, 2020 目的探讨血清异常凝血酶原(PIVKA-II)在胰腺癌诊断中的应用价值。方法收集2018年1月至2019年6月于北京清华长庚医院初次诊断为胰腺癌的住院患者57例,胰腺炎患者50例,健康体检者50例,分别用化学发光法检测PIVKA-II、CA199、CEA、AFP,比较4个指标在胰腺癌组、胰腺炎组和健康对照组的差异,并作ROC曲线,比较PIVKA-II、CA199、CEA鉴别诊断胰腺良恶性疾病的效能;根据肿瘤位置,将胰腺癌组分为胰头癌组和胰体胰尾癌组,比较两组PIVKA-II、CA199、CEA水平的差异 ...
董静肖 +3 more
doaj
Femoral PEComa Treated With Combined Surgery and Radiotherapy: A Case Report
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal tumor, and primary involvement of the bone is exceptionally uncommon. In this report, a case of malignant PEComa arising from the femur in an elderly patient is described.
Yanluqi He +4 more
wiley +1 more source
Serum IL-17A as a Diagnostic and Prognostic Biomarker in Colorectal Cancer: Development and Validation of a Multi-Indicator Model [PDF]
Objective: Colorectal cancer ranks as the third most prevalent malignancy globally. To address the limited sensitivity of conventional biomarkers, this study evaluated the clinical utility of preoperative serum interleukin-17A (IL-17A) in CRC diagnosis ...
Jia, Houjun, Li, Jiancheng
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International Medical Case Reports JournalHao Wu,1– 6 Xing-Hua Zhang,1,3– 6 Li-Ping Wang,7,8 Hong-Da Tian,1,3– 6 Gui-Rong Liu,1,3– 6 Dong-Hui Yang,9 Shu-Lin Liu1,3– 8,10 1Genomics Research Center (State-Province Key Laboratory of Biomedicine-Pharmaceutics of China), College of Pharmacy, Harbin ...
Wu H +6 more
doaj
Network Exploration of Correlated Multivariate Protein Data for Alzheimer\u27s Disease Association [PDF]
, 2017 Alzheimer Disease (AD) is difficult to diagnose by using genetic testing or other traditional methods. Unlike diseases with simple genetic risk components, there exists no single marker determining as to whether someone will develop AD.
Lane, Matthew J
core +1 more source