Results 91 to 100 of about 6,916 (199)

Inhibition of cancer cell growth by cyclin dependent kinase 4 inhibitors synthesized based on the structure of fascaplysin [PDF]

, 2006
Tryptamine derivatives, a new structural class of cyclin dependent kinase 4 inhibitors, have been identified during extensive biological screening of synthetic molecules.
Jenkins, Paul R., Maréchal, Jean-Didier, Aubry, C., Maréchal, Jean Didier, Jenkins, Paul, R., Sutcliffe, Michael J., Chaudhuri, Bhabatosh, Sutcliffe, Michael, J., Mahale, Sachin, Chaudhuri, B., Aubry, Carine, Mahale, S.   +11 more
core   +1 more source

Association Between Multi‐Laboratory Parameters Pre‐ and Post‐Treatment and Pathological Features and Their Values in Clinical Decision in Primary Hepatic Carcinoma

Journal of Clinical Laboratory Analysis, Volume 40, Issue 11, June 2026.
Primary hepatic cancer (PHC), especially hepatocellular carcinoma (HCC), is still a significant burden worldwide. The efficacy of diagnosis, treatment response monitoring, and prognostication using laboratory biomarkers is still a challenge. This study analyzed multi‐laboratory parameters pre‐ and post‐treatment and their associations with clinical and
Xiaowei Chi, Weifang Liu, Zihan Liu, Jie Liu   +3 more
wiley   +1 more source

血清异常凝血酶原在胰腺癌诊断中的应用价值研究

Zhongguo shiyan zhenduanxue, 2020
目的探讨血清异常凝血酶原(PIVKA-II)在胰腺癌诊断中的应用价值。方法收集2018年1月至2019年6月于北京清华长庚医院初次诊断为胰腺癌的住院患者57例,胰腺炎患者50例,健康体检者50例,分别用化学发光法检测PIVKA-II、CA199、CEA、AFP,比较4个指标在胰腺癌组、胰腺炎组和健康对照组的差异,并作ROC曲线,比较PIVKA-II、CA199、CEA鉴别诊断胰腺良恶性疾病的效能;根据肿瘤位置,将胰腺癌组分为胰头癌组和胰体胰尾癌组,比较两组PIVKA-II、CA199、CEA水平的差异 ...
董静肖, 崔世伟, 杨晓欢, 赵秀英   +3 more
doaj  

Successful Outcome of a Patient with Concomitant Pancreatic and Renal Carcinoma Receiving Secoisolariciresinol Diglucoside Therapy Alone: A Case Report

International Medical Case Reports Journal
Hao Wu,1– 6 Xing-Hua Zhang,1,3– 6 Li-Ping Wang,7,8 Hong-Da Tian,1,3– 6 Gui-Rong Liu,1,3– 6 Dong-Hui Yang,9 Shu-Lin Liu1,3– 8,10 1Genomics Research Center (State-Province Key Laboratory of Biomedicine-Pharmaceutics of China), College of Pharmacy, Harbin ...
Wu H, Zhang XH, Wang LP, Tian HD, Liu GR, Yang DH, Liu SL   +6 more
doaj  

检测肿瘤标志物、LDH、ADA对良恶性腹水鉴别诊断价值

Zhongguo shiyan zhenduanxue, 2005
目的探讨检测腹水肿瘤标志物、LDH、ADA对良恶性腹水的鉴别诊断价值。方法AFP、CEA、CA199、CA125用电化学方法进行检测,LDH采用酶法,ADA采用酶法。结果原发性肝癌患者腹水AFP、CEA、CA199、CA125明显高于良性腹水 ...
刘冬妍, 赵爱农, 王彦峰
doaj  

Construction of feature selection and efficacy prediction model for transformation therapy of locally advanced pancreatic cancer based on CT, 18F-FDG PET/CT, DNA mutation, and CA199

Background Immunotherapy and radiotherapy play crucial roles in the transformation therapy of locally advanced pancreatic cancer; however, the exploration of effective predictive biomarkers has been unsatisfactory. With the rapid development of radiomics,
Liang Qi, Jiayao Ni, Jian He, Juan Du, Baorui Liu, Xiang Li, Yali Du, Qing Gu   +7 more
core   +1 more source

Serum IL-17A as a Diagnostic and Prognostic Biomarker in Colorectal Cancer: Development and Validation of a Multi-Indicator Model [PDF]

Objective: Colorectal cancer ranks as the third most prevalent malignancy globally. To address the limited sensitivity of conventional biomarkers, this study evaluated the clinical utility of preoperative serum interleukin-17A (IL-17A) in CRC diagnosis ...
Li, Jiancheng, Jia, Houjun
core   +1 more source

Clinical and pathological characteristics of 7 cases of colorectal cancer in organ transplant recipients

, 2023
[Objectives] To analyze the clinical and pathological characteristics of colorectal cancer in organ transplant recipients and provide references for clinical diagnosis and treatment.
Gong Haifeng, Zhang Wei, Ji Liqiang, Liu Lianjie, Wang Ye, Jin Lu, Meng Ronggui, Zheng Kuo, Hao Liqiang, Li Shuyuan, Lou Zheng   +10 more
core   +1 more source

Changing patterns of Serum CEA and CA199 for Evaluating the Response to First-line Chemotherapy in Patients with Advanced Gastric Adenocarcinoma

Asian Pacific Journal of Cancer Prevention, 2015
This study was designed to investigate the value of CEA and CA199 in predicting the treatment response to palliative chemotherapy for advanced gastric cancer.We studied 189 patients with advanced gastric cancer who received first-line chemotherapy, measured the serum CEA and CA199 levels, used RECIST1.1 as the gold standard and analyzed the value of ...
Bo, He, Hui-Qing, Zhang, Shu-Ping, Xiong, Shan, Lu, Yi-Ye, Wan, Rong-Feng, Song   +5 more
openaire   +3 more sources

Characteristics and miR-30c expression in colon cancer patients.

, 2015
* The correlation between miR-30c and CEA and CA199 is determined by Spearman’s correlation.Characteristics and miR-30c expression in colon cancer patients.
Lei Yu (70258), Xiaochen Jiang (709768), Yinggang Chen (492235), Xu Gao (51798), Chendan Zou (709769), Qingchao Tang (492232), Rui Huang (141490), Xishan Wang (282956), Dandan Qin (692103), Guiyu Wang (492234), Qian Zhang (49333)   +10 more
core   +1 more source