Results 71 to 80 of about 6,916 (199)

Combined Determination of Carbohydrate Antigen 199 and SirT1 Based on an Electrochemiluminescence Immunosensor

open access: yesInternational Journal of Electrochemical Science, 2017
In this work, a multi-functionalized graphene oxide (GO) material, where N-(4-aminobutyl)-N-ethylisoluminol (ABEI) and either a CA199 antibody or a SirT1 antibody were chemically bound to the surface of magnetic GO (nanoFe3O4@GO), was fabricated as a one-
Wei Shao, Xiuli Sui, Guowei Wang
doaj   +1 more source

Survival Outcomes of Patients With Colorectal Cancer After Primary Surgery: A Population‐Based Study in Hainan, China

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Colorectal cancer (CRC) is a major public health burden in Hainan Province due to its high incidence and mortality, yet region‐specific prognostic data are lacking. This study evaluates prognostic factors in postsurgical CRC patients to guide localized prevention and treatment.
Le Du   +12 more
wiley   +1 more source

Therapeutic and Predicted Significance of PKLR in Patients With Cholangiocarcinoma

open access: yesCancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Cholangiocarcinoma (CCA) is a highly heterogeneous malignancy with a poor prognosis. However, the molecular mechanisms underlying CCA and its treatment options remain unclear and limited. Aims This study aims to identify novel prognostic biomarkers and potential therapeutic targets for CCA through transcriptomics and whole‐exome ...
Biyan Gong   +7 more
wiley   +1 more source

CA125、CA199和CEA联合检测在卵巢癌诊断中的临床意义

open access: yesZhongguo shiyan zhenduanxue, 2014
目的探讨糖类抗原125(CA125)、糖类抗原199(CA199)和癌胚抗原(CEA)联合检测在卵巢癌诊断中的临床意义。方法选择我院收治的卵巢癌患者80例为研究组,卵巢良性疾病患者80例为对照A组,来院检查的健康者80例为对照B组,采用化学发光法对3组血清中CA125、CA199和CEA含量进行测定。比较3种肿瘤标志物联合检测与单项检测CA125的诊断意义。结果研究组3种肿瘤标志物水平及阳性率均显著高于对照组,且有显著性差异(P0.05)。研究组单项检测及联合检测卵巢癌的阳性率均显著高于两对照组 ...
姜靖, 邓晓阳, 胡晓蕙
doaj  

Clinical Value of Combined Multi-Indicator Tests in Diagnosis of Benign Ovarian

open access: yesInternational Journal of General Medicine, 2023
Lunyun Yang,1 Lin Du,2 Bailong Hou,1 Xiaoqin Niu,1 Wei Wang,1 Weifeng Shen1 1Department of Laboratory Medicine, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, People’s Republic of China; 2The Third Xiangya Hospital of Central South ...
Yang L   +5 more
doaj  

Development and validation of individualized prognostic nomograms based on the tumour‐stroma percentage in patients with proximal and distal gastric cancer: A population‐based study

open access: yesClinical and Translational Discovery, Volume 6, Issue 4, August 2026.
1. TSP is associated with survival outcomes in gastric cancer. 2. TSP independently predicts prognosis in proximal gastric cancer. 3. Location‐specific nomograms enable individualized survival prediction for PGC and DGC. Abstract Background Gastric cancers (GCs) arising in the proximal and distal stomach are increasingly recognized as biologically and ...
Yueling Wang   +7 more
wiley   +1 more source

The Significance of the Regulation Between tRF‐31‐U5YKFN8DYDZDD and BMPER in the Pathogenesis of Gastric Cancer (GC)

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 16, August 2026.
ABSTRACT tsRNAs are a kind of small non‐coding single‐stranded RNA, which play an important role in many kinds of tumours. Previous studies have identified that tRF‐31‐U5YKFN8DYDZDD can be used as a novel tumour biomarker for the diagnosis and prognosis of gastric cancer (GC).
Yuejiao Huang   +7 more
wiley   +1 more source

Clinicopathological and molecular characterization of HPV‐associated cervical poorly cohesive carcinoma: a rare aggressive entity

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Primary signet‐ring cell carcinoma and poorly differentiated adenocarcinoma with poorly cohesive morphology in the cervix are rare conditions, and their clinicopathological features remain poorly described. This study defines primary cervical poorly differentiated adenocarcinomas meeting the diagnostic criteria for poorly cohesive carcinoma as
Wei Liu   +14 more
wiley   +1 more source

Table_1_The Value of Serum Tumor Markers and Blood Inflammation Markers in Differentiating Pancreatic Serous Cystic Neoplasms and Pancreatic Mucinous Cystic Neoplasms.docx

open access: yes, 2022
Although many studies have emphasized the prognostic and diagnostic value of tumor markers and various inflammation-related markers, their clinical significance in differentiating benign and malignant pancreatic cystic neoplasms (PCNs) remains to be ...
Sihai Chen (1490641)   +7 more
core   +1 more source

Approaching Gold‐Standard Sensitivity in a Portable and Versatile Gold Nanoprisms Thermoplasmonic Platform for Lateral Flow Detection of Biomolecules

open access: yesSmall, Volume 22, Issue 41, 22 July 2026.
This study presents a plasmonic thermal lateral flow (ThermoLFA) biosensor for ultrasensitive, early detection of biomolecules. By combining plasmonic gold nanoprisms (AuNPrs) and near‐infrared (NIR) laser activation, it enhances signal output beyond conventional LFAs.
Carlos Cuestas Ayllón   +5 more
wiley   +1 more source

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