Results 61 to 70 of about 7,271 (215)

Isolated Esophageal Langerhans Cell Histiocytosis in an Adult: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Langerhans cell histiocytosis (LCH) is an inflammatory neoplastic disease characterized by the clonal proliferation of Langerhans cells, with a very low incidence, mostly in children. LCH in adults is extremely rare, with esophageal involvement being particularly uncommon.
Jingxin Ye   +4 more
wiley   +1 more source

IgG4-related disease and the current status of diagnostic approaches [PDF]

open access: yes, 2012
IgG4-related disease is a newly recognized systemic disease characterized by involving a wide range of organs. It includes the pancreas, biliary tree, salivary glands, periorbital tissues, upper aerodigestive tract, retroperitoneum, mediastinum, aorta ...
Du, Haitao   +4 more
core  

Effect of First‐Line Chemotherapy Alone Versus First‐Line Chemotherapy Plus Radiotherapy on Survival in Patients With Locally Advanced Pancreatic Cancer in the IMRT Era: A Retrospective Cohort Study

open access: yesCancer Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background The role of intensity‐modulated radiotherapy (IMRT) and novel combination chemotherapy regimens in locally advanced pancreatic cancer (LAPC) remains unclear. In this study, we focused on comparing survival between first‐line chemotherapy alone and first‐line chemotherapy plus IMRT in patients with LAPC.
Zihao Liu   +3 more
wiley   +1 more source

CTC检测联合CA199、IGFBP2检测对胰腺癌的诊断价值

open access: yesZhongguo shiyan zhenduanxue, 2022
目的 研究循环肿瘤细胞(CTC)检测联合糖类抗原199(CA199)、胰岛素样生长因子结合蛋白2(IGFBP2)检测对胰腺癌的诊断价值。方法 选取2019年12月-2020年12月在秦皇岛市第一医院就诊的胰腺癌80例,为胰腺癌组,选取同期就诊的胰腺良性疾病患者60例,为胰腺良性疾病组,另外选取健康体检志愿者30例,为对照组。所有患者均采集静脉血检测CTC、CA199、IGFBP2水平,分析CTC、CA199、IGFBP2水平与胰腺癌发病的关系。结果 胰腺癌组CA199 ...
doaj  

Clinical Value of Combined Multi-Indicator Tests in Diagnosis of Benign Ovarian

open access: yesInternational Journal of General Medicine, 2023
Lunyun Yang,1 Lin Du,2 Bailong Hou,1 Xiaoqin Niu,1 Wei Wang,1 Weifeng Shen1 1Department of Laboratory Medicine, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, People’s Republic of China; 2The Third Xiangya Hospital of Central South ...
Yang L   +5 more
doaj  

Combined Determination of Carbohydrate Antigen 199 and SirT1 Based on an Electrochemiluminescence Immunosensor

open access: yesInternational Journal of Electrochemical Science, 2017
In this work, a multi-functionalized graphene oxide (GO) material, where N-(4-aminobutyl)-N-ethylisoluminol (ABEI) and either a CA199 antibody or a SirT1 antibody were chemically bound to the surface of magnetic GO (nanoFe3O4@GO), was fabricated as a one-
Wei Shao, Xiuli Sui, Guowei Wang
doaj   +1 more source

Nanoparticles in microdroplets: Recent advances in microfluidic generators for producing functional microbeads

open access: yesDroplet, Volume 5, Issue 2, April 2026.
Functional hybrid microbeads with electrical, magnetic, and/or optical responsiveness have emerged as versatile platforms for biotechnology. This review highlights recent advances in microfluidic technologies for producing such microbeads, with a focus on incorporating functional nanoparticles in microdroplet systems.
  Bayinqiaoge   +2 more
wiley   +1 more source

A Hybrid Qualitative–Quantitative FMEA Model for Risk Management in Clinical Laboratory Automation: A Case Study Integrating ISO 15189:2022

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 7, April 2026.
This study integrates ISO 15189:2022 requirements with failure mode and effects analysis (FMEA) to establish a comprehensive risk management framework for multibrand total laboratory automation (TLA) systems. By combining quantitative operational data with expert evaluation, an objective and reproducible occurrence scoring strategy was developed ...
Mengqi Wei   +5 more
wiley   +1 more source

CA125、CA199和CEA联合检测在卵巢癌诊断中的临床意义

open access: yesZhongguo shiyan zhenduanxue, 2014
目的探讨糖类抗原125(CA125)、糖类抗原199(CA199)和癌胚抗原(CEA)联合检测在卵巢癌诊断中的临床意义。方法选择我院收治的卵巢癌患者80例为研究组,卵巢良性疾病患者80例为对照A组,来院检查的健康者80例为对照B组,采用化学发光法对3组血清中CA125、CA199和CEA含量进行测定。比较3种肿瘤标志物联合检测与单项检测CA125的诊断意义。结果研究组3种肿瘤标志物水平及阳性率均显著高于对照组,且有显著性差异(P0.05)。研究组单项检测及联合检测卵巢癌的阳性率均显著高于两对照组 ...
姜靖, 邓晓阳, 胡晓蕙
doaj  

The Efficacy and Safety of Hepatic Arterial Infusion Chemotherapy for Mismatch Repair Proficient (pMMR)/Microsatellite Stable (MSS) Colorectal Cancer Liver Metastases (CRLM)

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Purpose To assess the effectiveness and safety of hepatic arterial infusion chemotherapy (HAIC) in patients with mismatch repair proficient (pMMR)/microsatellite stable (MSS) colorectal cancer liver metastases (CRLM) who are resistant to standard treatments.
Yawei Li   +5 more
wiley   +1 more source

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