Results 21 to 30 of about 6,616 (134)

Sensing and Interaction of His-Tagged CA19-9 Antigen with Graphene-Modified Electrodes

open access: yesChemosensors, 2020
The electrochemical oxidation of CA19-9 tagged with L-Histidine (CA199-His) was investigated for the first time with screen-printed electrodes (DS) modified with graphene oxide (DS/GO) or thermally reduced graphene oxide (DS/TRGO).
Mihaela Mic   +6 more
doaj   +1 more source

糖脂代谢、ca199、ca242及ca50与2型糖尿病患者骨代谢异常的相关性研究

open access: yesZhongguo shiyan zhenduanxue, 2022
目的 对糖尿病合并骨质疏松与ca199、ca242、ca50相关性进行探究。方法 选择2017年6月-2020年3月至应急总医院就诊的176例2型糖尿病患者作为研究对象,根据双能X线吸收法(DEXA)测定的骨密度检查结果将全部患者分为A组(骨量正常,n=61)、B组(骨量减少,n=53)、C组(骨质疏松,n=62)。比较各组糖脂代谢指标、肿瘤标记物(ca199、ca242、ca50)水平差异,并对骨密度与上述指标进行相关性分析。结果 FBG、2hPBG、HbA1c、TC、TG、LDL-C、ca199 ...
郭丽娟, 葛双雷, 许慧, 朱筠
doaj  

The significance of elevated plasma expression of microRNA 106b~25 clusters in gastric cancer. [PDF]

open access: yesPLoS ONE, 2017
OBJECTIVE:Concentrating on oncogenic role and increased plasma expression of microRNA(miR) 106b~25 clusters (involving miR 106b, miR 93 and miR 25), we evaluated significance of the over-expression of plasma miR 106b~25 in GC.
Fangxuan Li   +3 more
doaj   +1 more source

Microfluidic Molecular Diagnostic Chips: Functional Modules, Integration Strategies, and Emerging Applications

open access: yesSmall Methods, EarlyView.
This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo   +7 more
wiley   +1 more source

Potential of combination of DCE-MRI and DWI with serum CA125 and CA199 in evaluating effectiveness of neoadjuvant chemotherapy in breast cancer

open access: yesWorld Journal of Surgical Oncology, 2021
Background To determine the potential of the combination of DCE-MRI imaging method with DWI and serum CA125 and CA199 levels in the evaluation of the efficacy of neoadjuvant chemotherapy in breast cancer patients.
Jun Zhang   +4 more
doaj   +1 more source

Efficacy and related factors of levonorgestrel‐releasing intrauterine system combined with metformin in fertility‐preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 396-407, October 2026.
Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu   +5 more
wiley   +1 more source

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye   +9 more
wiley   +1 more source

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

open access: yesAdvanced Science, Volume 13, Issue 54, 28 September 2026.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng   +20 more
wiley   +1 more source

胃癌患者血清中IGF-1与CEA、CA125、CA199、CA724水平的相关性分析及在胃癌诊断中的意义

open access: yesZhongguo shiyan zhenduanxue, 2021
目的探讨IGF-1在胃癌患者血清中的表达及与肿瘤标志物CEA、CA125、CA199和CA724的相关性。方法电化学发光法检测血清肿瘤标志物CEA、CA125、CA199、CA724的水平;采用酶联免疫分析法检测血清中IGF-1的水平;Pearson分析IGF-1与CEA、CA125、CA199和CA724的相关性。结果胃癌患者血清中CEA、CA125、CA199、CA724及IGF-1的水平均高于良性胃部疾病患者和健康对照组。胃癌Ⅲ期和Ⅳ期患者血清中CEA、CA125、CA199、CA724及IGF ...
王宁   +4 more
doaj  

A Deep Learning Framework Predicts Rectal Cancer Treatment Response via Pretreatment 3D Transrectal Ultrasound: A Multicenter Study

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Not all rectal cancer patients achieve pathological complete response (pCR) after neoadjuvant therapy, and the predictive potential of 3D transrectal ultrasound (TRUS) in this setting remains unexplored (A). Multi‐center pre‐treatment data were collected (B) and used to develop a semi‐supervised segmentation model and a 3D‐ResNet predictive model (C ...
Min Liu   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy