Results 31 to 40 of about 6,616 (134)
Advanced Science, Volume 13, Issue 45, 13 August 2026.ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang +9 more
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Advanced Science, Volume 13, Issue 47, 24 August 2026.This study applied AI to quantify multidimensional body composition from CT images in gastric cancer and healthy controls. Distinct sex‐specific patterns and disease‐related alterations were identified and were associated with survival. Higher muscle and fat measures were linked to improved outcomes.
Tianxiang Li +13 more
wiley +1 more source
CTC检测联合CA199、IGFBP2检测对胰腺癌的诊断价值
Zhongguo shiyan zhenduanxue, 2022 目的 研究循环肿瘤细胞(CTC)检测联合糖类抗原199(CA199)、胰岛素样生长因子结合蛋白2(IGFBP2)检测对胰腺癌的诊断价值。方法 选取2019年12月-2020年12月在秦皇岛市第一医院就诊的胰腺癌80例,为胰腺癌组,选取同期就诊的胰腺良性疾病患者60例,为胰腺良性疾病组,另外选取健康体检志愿者30例,为对照组。所有患者均采集静脉血检测CTC、CA199、IGFBP2水平,分析CTC、CA199、IGFBP2水平与胰腺癌发病的关系。结果 胰腺癌组CA199 ...
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血清CA199、HMGB1和PCT检测对胆总管结石继发急性胆管炎的预测价值探讨
Zhongguo shiyan zhenduanxue, 2023 目的 探讨血清糖类抗原199(CA199)、高迁移率族蛋白1(HMGB1)和降钙素原(PCT)联合检测对胆总管结石(CBDS)继发急性胆管炎(AC)的预测价值。方法 选取2020年6月至2022年6月天津市宝坻区人民医院收治的单纯性CBDS患者153例作为非AC组，43例CBDS继发AC患者作为AC组，另AC组根据AC严重程度分为轻度组(n=12)、中度组(n=24)和重度组(n=7)。比较AC组与非AC组，不同AC严重程度组血清CA199、HMGB1和PCT水平，并采用受试者工作特征(ROC ...
孙建贺, 赵鑫
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International Journal of Electrochemical Science, 2017 In this work, a multi-functionalized graphene oxide (GO) material, where N-(4-aminobutyl)-N-ethylisoluminol (ABEI) and either a CA199 antibody or a SirT1 antibody were chemically bound to the surface of magnetic GO (nanoFe3O4@GO), was fabricated as a one-
Wei Shao, Xiuli Sui, Guowei Wang
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Cancer Medicine, Volume 15, Issue 8, August 2026.ABSTRACT Background Colorectal cancer (CRC) is a major public health burden in Hainan Province due to its high incidence and mortality, yet region‐specific prognostic data are lacking. This study evaluates prognostic factors in postsurgical CRC patients to guide localized prevention and treatment.
Le Du +12 more
wiley +1 more source
Therapeutic and Predicted Significance of PKLR in Patients With Cholangiocarcinoma
Cancer Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background Cholangiocarcinoma (CCA) is a highly heterogeneous malignancy with a poor prognosis. However, the molecular mechanisms underlying CCA and its treatment options remain unclear and limited. Aims This study aims to identify novel prognostic biomarkers and potential therapeutic targets for CCA through transcriptomics and whole‐exome ...
Biyan Gong +7 more
wiley +1 more source
CA125、CA199和CEA联合检测在卵巢癌诊断中的临床意义
Zhongguo shiyan zhenduanxue, 2014 目的探讨糖类抗原125（CA125）、糖类抗原199（CA199）和癌胚抗原（CEA）联合检测在卵巢癌诊断中的临床意义。方法选择我院收治的卵巢癌患者80例为研究组,卵巢良性疾病患者80例为对照A组,来院检查的健康者80例为对照B组,采用化学发光法对3组血清中CA125、CA199和CEA含量进行测定。比较3种肿瘤标志物联合检测与单项检测CA125的诊断意义。结果研究组3种肿瘤标志物水平及阳性率均显著高于对照组,且有显著性差异（P0.05）。研究组单项检测及联合检测卵巢癌的阳性率均显著高于两对照组 ...
姜靖, 邓晓阳, 胡晓蕙
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Clinical Value of Combined Multi-Indicator Tests in Diagnosis of Benign Ovarian
International Journal of General Medicine, 2023 Lunyun Yang,1 Lin Du,2 Bailong Hou,1 Xiaoqin Niu,1 Wei Wang,1 Weifeng Shen1 1Department of Laboratory Medicine, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, People’s Republic of China; 2The Third Xiangya Hospital of Central South ...
Yang L +5 more
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Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.1. TSP is associated with survival outcomes in gastric cancer. 2. TSP independently predicts prognosis in proximal gastric cancer. 3. Location‐specific nomograms enable individualized survival prediction for PGC and DGC. Abstract Background Gastric cancers (GCs) arising in the proximal and distal stomach are increasingly recognized as biologically and ...
Yueling Wang +7 more
wiley +1 more source