Results 101 to 110 of about 110,913 (348)
Journal of Cachexia, Sarcopenia and Muscle, 2019 Background Cachexia is an important extra‐pulmonary manifestation of chronic obstructive pulmonary disease (COPD) presenting as unintentional weight loss and altered body composition.
Hoi Yee Kwan +9 more
doaj +1 more source
STAT3 in the systemic inflammation of cancer cachexia [PDF]
, 2016 Weight loss is diagnostic of cachexia, a debilitating syndrome contributing mightily to morbidity and mortality in cancer. Most research has probed mechanisms leading to muscle atrophy and adipose wasting in cachexia; however cachexia is a truly systemic
Bonetto, Andrea +2 more
core +1 more source
NAD+ repletion with niacin counteracts cancer cachexia
bioRxiv, 2022 Cachexia is a debilitating wasting syndrome and highly prevalent comorbidity in cancer patients. It manifests especially with energy and mitochondrial metabolism aberrations that promote tissue wasting.
M. Beltrà +13 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Landscape of clinical trials in cancer cachexia: assessment of trends from 1995–2024
BMC CancerBackground Cancer cachexia, a multifactorial syndrome characterized by unintentional weight loss, is a frequent complication of cancer that impacts patients’ quality of life and survival.
Ana Regina Cabrera +4 more
doaj +1 more source
Microbiology Spectrum, 2023 Cachexia is a lethal muscle-wasting syndrome associated with cancer and chemotherapy use. Mounting evidence suggests a correlation between cachexia and intestinal microbiota, but there is presently no effective treatment for cachexia.
Sung-Yu Wu +6 more
doaj +1 more source
Exploring metabolic dysfunction in chronic kidney disease [PDF]
, 2012 Impaired kidney function and chronic kidney disease (CKD) leading to kidney failure and end-stage renal disease (ESRD) is a serious medical condition associated with increased morbidity, mortality, and in particular cardiovascular disease (CVD) risk ...
Slee, Adrian D.
core +2 more sources
Journal of Cachexia, Sarcopenia and Muscle, 2021 Although systemic inflammation is an important feature of the cancer cachexia, studies on the association between systemic inflammation and prognostic of cancer cachexia are limited.
Qi Zhang +14 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Ubiquinol Reduces Muscle Wasting but Not Fatigue in Tumor-Bearing Mice [PDF]
, 2014 Purpose: Fatigue is the most common and distressing symptom reported by cancer patients during and after treatment. Tumor growth increases oxidative stress and cytokine production, which causes skeletal muscle wasting and cardiac dysfunction. The purpose
Clark, Yvonne +3 more
core +2 more sources