Results 81 to 90 of about 64,866 (299)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Physical exercise at the crossroad between muscle wasting and the immune system: implications for lung cancer cachexia

, 2022
Cachexia is a syndrome characterized by involuntary weight loss and wasting of skeletal muscle mass. It is associated with worse overall survival and quality of life.
van de Worp W. R. P. H., Cortiula F., Hendriks L. E. L., Schols A. M. W. J., Vaes R. D. W., Langen R. C. J., De Ruysscher D.   +6 more
core   +1 more source

A Knowledge‐Based Approach for Understanding and Managing Additive Manufacturing Data

Advanced Engineering Materials, EarlyView.
Additive manufacturing processes generate a large amount of data. Effectively managing, understanding, and retrieving information from this data remains a major challenge. Therefore, we propose an ontology‐based approach to integrate heterogeneous data, enable semantic queries, and support decision‐making.
Mina Abd Nikooie Pour, Prithwish Tarafder, Anton Wiberg, Huanyu Li, Johan Moverare, Patrick Lambrix   +5 more
wiley   +1 more source

Skeletal muscle regeneration is impaired in patients with cancer-associated cachexia

, 2020
Cancer-associated cachexia is defined by loss of skeletal muscle mass with or without body fat loss. The skeletal muscle regenerative processes appear to be dysregulated in cancer cachexia, with increased muscle progenitor cell proliferation, resulting ...
Simões E, Seelaender M., Gabriela de Castro GS, Tokeshi F, Coletti D, Correia-Lima J, Pires Gomes S, Alcantara PS, Otoch JP   +8 more
core  

Current Status and Challenges in Data Collection for Aerospace Coatings Deposited by Plasma Spraying

Advanced Engineering Materials, EarlyView.
An innovative approach has been integrated into the GRENAT project to optimize plasma spraying and coating performance. Raw materials are accelerated and melted in the plasma generated by torches, creating coatings. Monitoring sensors collect process data which are combined with ex situ characterization data.
Lila Randriamananjara, Vincent Rat, Quentin Dubreuil, Patrice Valorge, Simon Goutier, Alain Denoirjean, Olivier Messe, Céline Ruelle, Jean‐Philippe Poli   +8 more
wiley   +1 more source

SRF role as a mechano-transductor in response to exercise in cancer cachexia [PDF]

, 2019
Introduction: Recent studies showed that physical activity increased survival in cancer patient and animal models of cancer cachexia. The underlying mechanisms, however, are still largely unknown. Methods: To identify signalling pathways involved in
Sotiropoulos A, Adamo S, Li Z, Hassani M, Coletti D, Benoni A, Xue Z, Parlakian A   +7 more
core  

Cachexia

, 2022
The diagnosis of cachexia is based on loss of body weight and low body mass index plus at least three out of five additional criteria: decrease in muscle strength, fatigue, anorexia, low lean body mass, and abnormal biochemistry.
Calvani R., Marzetti E.
core   +1 more source

AWGC2023 cachexia consensus as a valuable tool for predicting prognosis and burden in Chinese patients with cancer

Journal of Cachexia, Sarcopenia and Muscle
Background The Asian Working Group for Cachexia (AWGC) proposed the first consensus report on diagnostic criteria for cachexia in Asians in 2023. However, the current consensus lacks cohort evidence to validate its effectiveness and practicality.
Hailun Xie, Lishuang Wei, Guotian Ruan, Heyang Zhang, Jinyu Shi, Shiqi Lin, Chenan Liu, Xiaoyue Liu, Xin Zheng, Yue Chen, Junqiang Chen, Hanping Shi   +11 more
doaj   +1 more source

Cachexia: A new definition

Clinical Nutrition, 2008
On December 13th and 14th a group of scientists and clinicians met in Washington, DC, for the cachexia consensus conference. At the present time, there is no widely agreed upon operational definition of cachexia. The lack of a definition accepted by clinician and researchers has limited identification and treatment of cachectic patient as well as the ...
EVANS WJ, MORLEY JE, ARGILÉS J, BALES C, BARACOS V, GUTTRIDGE D, JATOI A, KALANTAR ZADEH K, LOCHS H, MANTOVANI G, MARKS D, MITCH WE, MUSCARITOLI, Maurizio, NAJAND A, PONIKOWSKI P, ROSSI FANELLI, Filippo, SCHAMBELAN M, SCHOLS A, SCHUSTER M, THOMAS D, WOLFE R, ANKER   +21 more
openaire   +6 more sources

Modular Critical Element Recycling Platform Using a Nanoporous Additively Manufactured Gyroid

Advanced Engineering Materials, EarlyView.
A modular recycling platform integrates 3D‐printed nanoporous gyroid structures to enable efficient critical element recovery. This system utilizes a hierarchical architecture, combining macroscopic channels with polymerization‐induced nanoscale porosity. By systematically tuning structural wall thickness and resin formulation, the platform achieves an
Xiangyu Gao, Keldy Mason, Mert Gülçür, Rachel Paddock‐Lamb, Prince Alvin Fofanah, Zachariah A. Page, Michael Cullinan   +6 more
wiley   +1 more source