Results 121 to 130 of about 53,962 (242)

Impact of Tunisian Fermented Zgougou and Related Lactobacilli on Caco-2 Cell Barrier Integrity: Upregulation of Key Tight Junction Proteins. [PDF]

Food Sci Nutr
Missaoui J, Liso M, Lataoui M, Limongelli R, Minervini F, Achour L, De Angelis M.   +6 more
europepmc   +1 more source

Self‐Assembly of Therapeutic Peptides for Enhanced Cancer Therapy: Strategies, Therapeutic Performance, and Future Perspectives

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Therapeutic peptide self‐assembly is governed by multiple non‐covalent interactions, enabling the construction of diverse supramolecular structures. These self‐assembled systems can be engineered through spontaneous self‐assembly of monomers, co‐assembly, or stimulus‐responsive strategies to improve tumor delivery efficiency.
Yuelin Fang, Xue Wan, Shihe Wang, Honglan Dai, Huiling Zeng, Nan Chen, Xinxin Zhang   +6 more
wiley   +1 more source

Mechanisms of Cell Uptake and Transport of Xanthophylls in the Caco-2 Cell Model. [PDF]

Nutrients
Wu F, Chen N, Peng Y, Li M, Ni Y, Li T, Liu R, Wen X.   +7 more
europepmc   +1 more source

Astragaloside IV and Ferroptosis Modulation in Pathological Cardiac Hypertrophy: Current Evidence, an Integrative Hypothesis, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Pathological cardiac hypertrophy is initially an adaptive response to sustained mechanical, neurohormonal, or metabolic stress; however, it can progress to fibrosis, contractile dysfunction, arrhythmia, and heart failure. Ferroptosis is a type of regulated cell death caused by iron‐dependent phospholipid peroxidation.
Pengbo Liu, Yongzhi Deng
wiley   +1 more source

Interface-engineered Caco-2 cell culture on a collagen-coated liquid-liquid interface in a microfluidic device. [PDF]

Beilstein J Nanotechnol
Kuriu S, Kim SH.
europepmc   +1 more source

Immunometabolic Modulation by Low‐Dose Sodium Butyrate: PI3K/Akt/mTOR Signalling Orchestrates Macrophage Polarization to Protect Against Clostridioides difficile Colitis

Immunology, Volume 179, Issue 4, Page 594-608, December 2026.
Clostridioides difficile toxins TcdA and TcdB enter intestinal epithelial cells (IECs) via specific receptors, disrupt tight‐junction integrity and activate PI3K/Akt/mTOR signalling, promoting inflammasome assembly and IL‐1β release. Toxin‐induced IEC apoptosis further weakens the epithelial barrier.
Sisi Zhang, Zhou Jingxiang, Caixia Tan, Yuanyuan Xiao, Ju Zou, Biyue Tian, Anhua Wu, Chunhui Li   +7 more
wiley   +1 more source

The Transepithelial Transport and Transport Pathways of Free and Bound Nε-Carboxymethyllysine Using a Caco-2 Cell Monolayer Model. [PDF]

Foods
Yuan X, Nie C, Zhai R, Tu A, Cao X, Zhang L, Li J.   +6 more
europepmc   +1 more source

Divergent Roles of PIK3C3 in KRAS‐Wild‐Type and KRAS‐Mutant Advanced Colorectal Cancer: Implications for 5‐Fluorouracil Sensitivity and Prognosis

Cancer Medicine, Volume 15, Issue 11, November 2026.
PIK3C3 plays divergent roles in KRAS‐WT and KRAS‐mutant CRCs, viz. targeting PIK3C3 suppresses KRAS/ERK pathway in KRAS‐WT CRC, while enhancing 5‐FU sensitivity in KRAS‐mutant CRC. ABSTRACT Introduction Phosphatidylinositol 3‐kinase catalytic subunit type 3 (PIK3C3) is central to autophagy, which supports cancer adaptation to environmental stresses and
Chien‐An Chu, Nan‐Haw Chow, Jiu‐Yao Wang, Chen Chang, Peng‐Chan Lin, Yu‐Min Yeh, Bo‐Wen Lin, Yi‐Wen Wang, Yun‐Hao Dai, Yi‐Lin Chen, Po‐Chuan Chen, Shang‐Hung Chen, Ren‐Hao Chan, Chung‐Liang Ho, Che‐Wei Hsu, Chung‐Ta Lee   +15 more
wiley   +1 more source

Therapeutic Potential of Propolis in Ulcerative Colitis: A Review of Preclinical Evidence

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review compiles preclinical evidence from studies that investigate the therapeutic potential of propolis extracts derived from different botanical origins, as well as their main bioactive constituents, in the context of ulcerative colitis. The observed beneficial effects are primarily attributed to their antioxidant, immunomodulatory, and anti ...
Thayná Fernandes Barros, Gabriel Gomes Vila Nova, Rosane Nassar Meireles Guerra, Flavia Raquel Fernandes do Nascimento, Afonso Gomes Abreu   +4 more
wiley   +1 more source

Caco-2 Cell Co-Culture Alters the Molecular Size of Igl1 and Its Extracellular Fragments in <i>Entamoeba histolytica</i>. [PDF]

Pathogens
Kato K, Kudo M, Unno H, Hatakeyama T, Tachibana H.   +4 more
europepmc   +1 more source