Results 101 to 110 of about 52,118 (265)

PENGARUH EKSTRAK DIKLOROMETAN JAHE (Zingiber officinale Roscoe) TERHADAP PENGIKATAN TOKSIN KOLERA B-subunit CONJUGASI (FITC) PADA RECEPTOR SEL HIBRIDOMA LV DAN CACO-2 [Effect of Ginger (Zingiber officinale Roscoe) Dichloromethane Extract on Inhibition of Cholera Toxin B-subunit Conjugated FITC Binding to Receptor on LV Hibridome and Caco-2 Cells]

Jurnal Teknologi dan Industri Pangan, 2003
Cholera toxin is main factor that responsibility of watery diarrhea. The objectives of this investigation was to study the effect of ginger extract (GDE) in blocking cholera toxin binding to receptors of LV hybridome and Caco-2 cells.Analysis of toxin
Radiati, L.E 1), Nabet, P , Franck, P 2), Nabet B 2), Capiaumont, J 2), Fardiaz, D 3), Zakaria, R.F 3), I. Sudirman 4), Hariyadi, R.D 3)   +7 more
doaj  

Plant responses to iron nutrition with emphasis on the underutilized crop tef (Eragrostis tef): A review

PLANTS, PEOPLE, PLANET, EarlyView.
Iron (Fe) deficiency limits the physical health, cognitive development, and economic output of billions of people globally, especially children and productive‐age women. Tef is an underutilized and stress‐resilient crop, which is becoming popular for its grains containing high bioavailable Fe and has the potential to mitigate Fe deficiency.
Muhammad Numan, David Remington, Ayalew Ligaba‐Osena   +2 more
wiley   +1 more source

Caco-2 Cell [PDF]

, 2020
openaire   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Molecular Modeling-Based Delivery System Enhances Everolimus-Induced Apoptosis in Caco‑2 Cells

ACS Omega, 2019
Marwan Abdelmahmoud Abdelkarim Maki, Palanirajan Vijayaraj Kumar, Shiau-Chuen Cheah, Yeong Siew Wei, Mayasah Al-Nema, Omer Bayazeid, Abu Bakar Bin Abdul Majeed   +6 more
doaj   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

Phytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong, Yuanxia Gao, Qian Li, Guangxin Chen, Dong Yang, Liping Zhao, Xiaojing Liu, Shumei Lin   +7 more
wiley   +1 more source

Phytochemicals as Multitarget Therapeutics in Pancreatic Cancer: Mechanisms, Clinical Evidence, and Translational Challenges

Phytotherapy Research, EarlyView.
Pancreatic cancer, particularly pancreatic ductal adenocarcinoma, is aggressive and often diagnosed late, making treatment challenging. This review highlights the potential of phytochemicals, such as curcumin and quercetin, as multitarget agents that influence key carcinogenic pathways. These compounds exhibit anticancer effects by inhibiting processes
Md. Rezaul Islam, Abdur Rauf, F. M. Shourav, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Kamala Badalova, Marcello Iriti   +7 more
wiley   +1 more source

Bioenhancer‐Driven Modulation of Membrane Dynamics Improves B‐Vitamin Uptake in Caco‐2 Cells

ChemFoodChem
Enhancing the bioavailability of B vitamins can increase their biological efficacy while reducing resource use in supplement production. Bioavailability can be improved through strategies such as microencapsulation, micellization, or the application of ...
Verena Preinfalk, Bernhard Blank‐Landeshammer, Marina Bishara, Sigrid Ihninger, Katja Essl, Stefanie Atzmüller, Mara Heckmann, Marcus Iken, Mario Brameshuber, Julian Weghuber   +9 more
doaj   +1 more source

Farnesoid X receptor prevents hyperuricemia via activating ATP‐binding cassette subfamily G member 2

Rheumatology &Autoimmunity, EarlyView.
Farnesoid X receptor (FXR) activation reduces serum uric acid levels by upregulating the intestinal urate transporter ATP‐binding cassette subfamily G member 2 (ABCG2). These findings uncover a novel metabolic pathway for urate excretion and suggest that FXR agonists (e.g., obeticholic acid), represent a promising therapeutic strategy for the treatment
Rui Li, Guo Tang, Ye Yu, Guang‐Liang Chen, Liangjing Lu, Juan Wang   +5 more
wiley   +1 more source