Results 121 to 130 of about 52,118 (265)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Ramucirumab induces apoptosis in Caco-2 cells via mitochondrial impairment and caspase activation. [PDF]

Saudi Pharm J
Al-Dogmi AM, Al-Anazi KM, Qamar W, Farah MA.   +3 more
europepmc   +1 more source

The effects of β-caryophyllene on butyrate utilization and metabolism in Caco-2 cells. [PDF]

Sci Rep
Scroggins H, Kent-Dennis C, May J, Harmon DL, Klotz JL.   +4 more
europepmc   +1 more source

Temporal transcriptomic profiling identifies core regulators in cytokine-induced gut barrier disruption in differentiated Caco-2 cells. [PDF]

Inflamm Res
Yoon HS, Ma S, Kanke M, Wu WJ, Hoang U, Tan JA, Wilks A, Patel P, Chandra S, Luo X, Lu D, Martin S, Wilson M, Van Lookeren Campagne M, Li CM, Kao CY.   +15 more
europepmc   +1 more source

Transepithelial Transport of Caffeoylquinic Acids in Caco-2 Cells: Structure Dependence and Modulation by Dietary Flavonoids. [PDF]

Foods
Zhao S, Zhang J, Huang Y, Yuan Y, Wu T, Pan S, Xu X.   +6 more
europepmc   +1 more source

Whole Wheat Flour Components Intervention Against Lead Toxicity: Impacts on Metal Bioavailability and Protection of the Intestinal Epithelial Barrier

Food Frontiers, Volume 7, Issue 5, September 2026.
ABSTRACT Consumption of whole wheat flour promotes lead excretion, yet the functional components reducing lead bioavailability and their protective mechanisms remain unclear. To identify these components and to validate whether their mechanism is related to protection of the intestinal barrier, this study established an in vitro model combining ...
Zhiyin Xiao, Tianhang Huang, Fengjiao Fan, Jian Ding, Xiaoyi Jiang, Xinyang Sun, Peng Li, Yong Fang   +7 more
wiley   +1 more source

Oxidative and Inflammatory Damage by Environmental Polyethylene Microplastics in Caco-2 Cells Is Prevented by Polyphenol-Rich Limoncella Apple Extract. [PDF]

Oxid Med Cell Longev
Lama S, Venditti M, Biasi A, Lenti C, Najahi H, Banni M, Tenore GC, Novellino E, Stiuso P.   +8 more
europepmc   +1 more source

Hawthorn Polyphenol Nanoparticles Alleviate Exercise‐Induced Fatigue by Modulating Energy Metabolism and the Gut Microbiome in Mice

Food Frontiers, Volume 7, Issue 5, September 2026.
Hawthorn polyphenol nanoparticles (HPN) were prepared using an antisolvent method and layer‐by‐layer self‐assembly. HPN alleviates exercise‐induced fatigue in a weight‐bearing swimming model. Its mechanism of action is associated with reduced levels of BUN, MDA, and cortisol, and enhancing the activity of SOD, CAT, and modulating the abundance and ...
Chun Zhang, Yan Wang, Jiancheng Ma, Yihong Chen, Donglin Shi, Hao Wang, Xuedong Chang, Suwen Liu, Lina Dong   +8 more
wiley   +1 more source

Mechanistic Insights into Piperine-Driven Oxidative Stress, Autophagy Activation and Anti-Migration Effects in Caco-2 Cells. [PDF]

Molecules
Sudan H, Passaponti S, Casini I, Romagnoli R, Cresti L, Gentile M, Frosini M, Aloisi AM.   +7 more
europepmc   +1 more source

Fisetin Attenuates Amyloid‐Beta‐Induced Neurotoxicity in Human Neuroblastoma SH‐SY5Y Cells: Integrating In Silico Target Prediction and In Vitro Validation

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
The in‐silico data showed that fisetin binds stably with the autophagy receptors and synaptic density regulators. Further, in‐vitro data confirmed the restoration of Aβ1‐42 disrupted autophagy by fisetin. Fisetin restored the oxidative stress and ion channels, along with a reduction of AChE activity.
Charu Jaiswal, Ishika Singh, Abhishek Kumar Singh   +2 more
wiley   +1 more source