Results 141 to 150 of about 54,220 (246)

Temporal transcriptomic profiling identifies core regulators in cytokine-induced gut barrier disruption in differentiated Caco-2 cells. [PDF]

Inflamm Res
Yoon HS, Ma S, Kanke M, Wu WJ, Hoang U, Tan JA, Wilks A, Patel P, Chandra S, Luo X, Lu D, Martin S, Wilson M, Van Lookeren Campagne M, Li CM, Kao CY.   +15 more
europepmc   +1 more source

Comprehensive Evaluation of Gastrointestinal Factors Influencing the Stability and Function of mRNA‐Encapsulated Lipid Nanoparticles

Drug Development Research, Volume 87, Issue 7, November 2026.
ABSTRACT Owing to the intrinsic instability of mRNA, its routes of administration are limited, and to date, only injectable delivery has been clinically applied. In contrast, oral administration exposes mRNA to a variety of substances in the gastrointestinal (GI) tract.
Toma Shinkai, Koki Ogawa, Mohamed S. Mohamed, Tetsuya Ozeki   +3 more
wiley   +1 more source

Tormentil Rhizome Ethanolic Extract and Its Gut Microbiota-Derived Metabolites: Modulation of Tight Junction Integrity and Anti-Inflammatory Potential in Caco-2 Cells. [PDF]

J Agric Food Chem
Kruk A, Grześkowiak Ł, Vlasova I, Kostenko Y, Zentek J, Granica S, Piwowarski JP.   +6 more
europepmc   +1 more source

Salicylic Acid as a Food‐Derived Bioactive Constituent of Tiaoqi Daozhi Decoction: A Potential Functional Food Ingredient to Restoring Gut Barrier Function in Constipation‐Predominant IBS

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
Tiaoqi Daozhi Decoction (TQDZD) is a classic formulation composed of eight medicine‐food homologous botanicals. UPLC‐MS/MS profiling identified 1962 non‐redundant compounds in its aqueous extract, predominantly phenolic acids and flavonoids, of which 107 metabolites were systemically bioavailable.
Min Duan, Lixia Huang, Yingyue Xu, Ya Huang, Xiaojun Yang   +4 more
wiley   +1 more source

Transepithelial Transport of Caffeoylquinic Acids in Caco-2 Cells: Structure Dependence and Modulation by Dietary Flavonoids. [PDF]

Foods
Zhao S, Zhang J, Huang Y, Yuan Y, Wu T, Pan S, Xu X.   +6 more
europepmc   +1 more source

Colonic Barrier Dysfunction and Inflammation Induced by Nano‐/Micro‐Plastics Fibers in Mice via the FAK/NF‐κB/iNOS and TLR4/NF‐κB/iNOS Pathways

Journal of Applied Toxicology, Volume 46, Issue 11, Page 4144-4159, November 2026.
ABSTRACT As emerging environmental contaminants, nano‐ and micro‐plastics (NMPs) have drawn increasing research attention due to potential hazards to organisms. Particle shape is a key factor influencing the toxic effects of NMPs, and NMPs of different shapes cause varying degrees of tissue damage. We investigated the specific mechanisms of polystyrene
Yuting Li, Shibo Bao, Puyang Huang, Jiahui Wang, Hongfeng Li, Yahong Liu, Kai Wang, Jianjun Du, Lingjun Yan, Guowei Pan, Wei Sun   +10 more
wiley   +1 more source

Oxidative and Inflammatory Damage by Environmental Polyethylene Microplastics in Caco-2 Cells Is Prevented by Polyphenol-Rich Limoncella Apple Extract. [PDF]

Oxid Med Cell Longev
Lama S, Venditti M, Biasi A, Lenti C, Najahi H, Banni M, Tenore GC, Novellino E, Stiuso P.   +8 more
europepmc   +1 more source

Iron treatment and human intestinal Caco-2 cells [PDF]

The American Journal of Clinical Nutrition, 2000
openaire   +2 more sources

Prognostic Value of LINC01140 in Colorectal Cancer and Its Regulatory Effect on Chemotherapy Resistance via miR‐942‐5p/NRXN1

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
Targeting the LINC01140/miR‐942‐5p/NRXN1 axis may be able to inhibit CRC progression by simultaneously regulating the functions of tumor cells and CAFs, which might significantly enhance the clinical efficacy of targeted therapy. ABSTRACT Long non‐coding RNAs play a wide role in colorectal cancer (CRC).
Jian Zhao, Songjie Liu, Bing Xu
wiley   +1 more source

Mechanistic Insights into Piperine-Driven Oxidative Stress, Autophagy Activation and Anti-Migration Effects in Caco-2 Cells. [PDF]

Molecules
Sudan H, Passaponti S, Casini I, Romagnoli R, Cresti L, Gentile M, Frosini M, Aloisi AM.   +7 more
europepmc   +1 more source