Results 141 to 150 of about 52,118 (265)

The Protective Effect of Quercetin on Hydrogen Peroxide-Induced Oxidative Damage in Caco-2 Cells Is Enhanced by Its Loading in Mesoporous Silica Nanoparticles. [PDF]

Pharmaceutics
Matadamas-Ortiz A, Di Pierro P, Sorrentino A, Caputo I, Paolella G, Montefusco A, Regalado-González C.   +6 more
europepmc   +1 more source

Evaluating the combined toxicity of Penicillium mycotoxins in absorption, metabolism, and excretion systems

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6523-6534, 30 August 2026.
Abstract BACKGROUND Penicillium mycotoxins, including ochratoxin A (OTA), citrinin (CIT), and cyclopiazonic acid (CPZ), frequently co‐occur in food commodities, contributing to chronic low‐level dietary exposure. However, current risk assessments often consider these toxins individually, overlooking potential interaction effects.
Carolina Sousa Monteiro, Eugénia Pinto, Miguel A Faria, Sara C Cunha   +3 more
wiley   +1 more source

Transcriptomic comparison of human intestinal organoids and Caco-2 cells in modeling nutrient absorption: insights from infant formula and breast milk. [PDF]

NPJ Sci Food
Wang X, Zhang W, Yang S, Zheng C, Wang Z, Yang G, Huang C, Yao H, Huang K, Yan Y, Jiang S, Sun J, Xie Q, Zhang Y, Li X, Wang H.   +15 more
europepmc   +1 more source

Molecular descriptor driven QSPR modeling of Papp, TEER and Efflux Ratio from Caco‐2 cells using machine learning for various phytochemicals

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6606-6616, 30 August 2026.
Abstract BACKGROUND The present study aimed to develop and validate quantitative structure–property relationship (QSPR) models for predicting permeability related bioavailability indicators including apparent permeability (Papp), trans‐epithelial electrical resistance (TEER) and efflux ratio (ER) based on molecular descriptors (n = 5003) of 83 ...
Jin‐Woo Kim, Rixing Cong, Jin‐Soo Park, Keunwan Park, Kyungsu Kang, Soon‐Mi Shim   +5 more
wiley   +1 more source

Phenolic Compounds of Grape Pomace Skin Released During SHIME Colonic Fermentation Shape the Transcriptomic Profile of Tight Junctions, Improving the Barrier Properties in Caco-2 Cells. [PDF]

Int J Mol Sci
Hidalgo M, Vera F, Concepción-Alvarez A, Rubio V, Railef B, Meneses-Pacheco J, Moreno M, Oyarzún M, Camargo AC, Bridi R, Fuenzalida K, Gonzales E, Pacheco I, Añazco C, Pulgar R, Porras O.   +15 more
europepmc   +1 more source

Topliss‐Guided Optimization of Acetanilide‐Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency‐Enhancing Motif

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Can an amide analog retain the high potency of the classic urea motif in soluble epoxide hydrolase inhibitors? Through a single unconventional switch, the introduction of the underexplored pentafluorosulfanyl group into an amide analog of TPPU, the authors restored high inhibitory potency.
Alba López‐Ruiz, Eugènia Pujol, Cristian Ramos, Valeria Rizzo, Christophe Morisseau, Cristina Val, Tiziana Ginex, Javier Vázquez, Sandra Codony, Andreea L. Turcu, Belén Pérez, Elena Sáez, Antonio Pineda‐Lucena, Bruce D. Hammock, F. Javier Luque, M. Isabel Loza, José Brea, Santiago Vázquez   +17 more
wiley   +1 more source

Valorization of Carménère Grape Pomace: Extraction, Microencapsulation, and Evaluation of the Bioactivity of Polyphenols in Caco-2 Cells. [PDF]

Int J Mol Sci
Valenzuela-Bustamante P, Cornejo P, Nolan N, Concepción-Alvarez A, Bridi R, Rincón-Cervera MÁ, Porras O, de Camargo AC, Arias-Santé MF.   +8 more
europepmc   +1 more source

Iron treatment and human intestinal Caco-2 cells [PDF]

The American Journal of Clinical Nutrition, 2000
openaire   +2 more sources

Pyridyl‐Thiazole‐Thiosemicarbazones as Antitrypanosomatidae Agents: Design, Synthesis, and In Silico Profiling

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
A novel pyridine–thiazole derivative, Compound 8, exhibited potent dual antitrypanosomatid activity. It demonstrated remarkable in vitro efficacy against Trypanosoma cruzi (IC50 = 1.0 µM) and L. amazonensis (IC50 = 3.9 µM). Molecular docking studies suggested interactions with heme and multiple molecular targets.
Anderson José Firmino Santos da Silva, Daiane Santiago da Cruz Olimpio, Lucas Manoel da Silva Sousa, Graziella Leite Brondani, Tacylla Lima Silva, Wéllyda Belmira de Lira Silva, Natáli Tereza Capistrano Costa, Marcelo Zaldini Hernandes, Policarpo Ademar Sales Junior, Valéria Rêgo Alves Pereira, Ana Cristina Lima Leite   +10 more
wiley   +1 more source

Remodeling of Bamboo (<i>Phyllostachys edulis</i>) Shoot Polysaccharides by <i>Monascus purpureus</i> Fermentation Enhances Antioxidant Protection in Caco-2 Cells. [PDF]

Foods
Long F, Hu Z, Luo H, Chu Z, Li S, Zhou Y, Li A, Luo F.   +7 more
europepmc   +1 more source