Results 161 to 170 of about 54,220 (246)

Evaluation of the Cytotoxicity of Biochar Aqueous Extract in Caco-2 Cells: Time-Dependent Regulation of Apoptosis, Associated with miRNA Modulation. [PDF]

Molecules
Amin S, Marcinkowska K, Wołoszyńska M, Opaliński S, Skrzypczak D, Wiercik P, Bobak Ł, Śmieszek A.   +7 more
europepmc   +1 more source

The role of iron in normal and impaired testicular function

Andrology, Volume 14, Issue 8, Page 2373-2387, November 2026.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Serotonin inhibits the influx of iron into cells by decreasing the expression of SLC11A2 in Caco-2 cells. [PDF]

Biomed Rep
Sugino Y, Ameku M, Kawanishi N, Nonen S.
europepmc   +1 more source

Impact of YAQ001 on the Gut Microbiome, Permeability and Markers of Systemic Inflammation in Patients With Cirrhosis

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background & Aims YAQ001 is a novel, non‐absorbable, gut‐restricted, multiporous, carbon bead adsorbent. Pre‐clinical studies and a clinical trial suggested its therapeutic potential and safety in patients with cirrhosis. This substudy aimed to explore the effects of YAQ001 on the gut microbiome and their exploratory association with ...
Jinxia Liu, Fernando Garcia‐Guevara, Jane Macnaughtan, Yi Jin, Ainhoa Ferret‐Miñana, Frederick Clasen, Nicholas Yuen, Ramón Garcia Maset, Javier Ramón‐Azcón, Annarein J. C. Kerbert, Theo Portlock, Javier Martinez, Abeba Habtesion, Alexandra Phillips, Francesco De Chiara, Ganesh Ingavle, Tom Baldwin, Cesar Jimenez, Giacomo Zaccherini, Katherine Husi, Miguel Rodriguez‐Gandia, Paul Cordero‐Sanchez, Junpei Soeda, Jude A. Oben, Karen Church, Jia V. Li, Aarti Jalan, Adria Juanola, Elsa Sola, Simon Eaton, Carrie Morgan, Thomas Avery, Michal Kowalski, Daniel Green, Amir Gander, Lindsey Ann Edwards, I. Jane Cox, Helena Cortez‐Pinto, Reiner Wiest, Francois Durand, Paolo Caraceni, Roberto Elosua, Joan Vila, Marco Pavesi, Vicente Arroyo, Nathan Davies, Rajeshwar P. Mookerjee, Susan Sandeman, Gautam Mehta, Julian R. Marchesi, Agustin Albillos, Jennifer L. Rohn, Fausto Andreola, Saeed Shoaie, Rajiv Jalan   +54 more
wiley   +1 more source

Molecular Insights into the Immunomodulating and Anticancer Mechanisms of Eremina desertorum (Forsskal, 1775) Mucin in HepG-2 and CACO-2 Cells. [PDF]

Asian Pac J Cancer Prev
Ibrahim AM, Atta SA, Megahed FAK.
europepmc   +1 more source

c‐Jun N‐Terminal Kinase‐2 Mediates Alcohol and Corticosterone‐Induced Tissue Injury at the Gut‐Liver Axis

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Alcohol activates JNK2, leading to epithelial TJ disruption. Corticosterone activates JNK2 and causes Paneth cell dysfunction. Depletion of α‐defensins due to Paneth cell dysfunction causes gut microbiota dysbiosis. Microbiota dysbiosis and TJ disruption lead to endotoxemia, systemic inflammation, and liver damage.
Lohitha Basa, Nitesh Shashikanth, Pradeep K. Shukla, Chandra Shekhar, Avtar S. Meena, Nathan Jones, Preeti Raju, Christopher Nguyen, Samhitha Swarna, Nathaniel B. Willis, Siddabasave Gowda B Gowda, Sue‐Chin Lee, Joseph F. Pierre, RadhaKrishna Rao   +13 more
wiley   +1 more source

Anti-inflammatory effects of oridonin on an <i>in vitro</i> model using LPS-treated human intestinal Caco-2 cells. [PDF]

Exp Ther Med
Wang M, Xu B, Li L, Wang Y, Li M.
europepmc   +1 more source

Backbone Steric Constraints Underlie High Passive Membrane Permeability of N‐Alkyl Peptides

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
Beyond amide hydrogen removal, steric constraints encoded in N/Cα‐dually substituted backbones are uncovered as a key determinant of passive membrane permeability in N‐alkyl peptides. These constraints restrict conformational freedom and sterically limit backbone hydration during membrane permeation.
Ayumi Inayoshi, Mariko Akiba, Marin Yokomine, Masatake Sugita, Koji Umezawa, Yuto Hirota, Yutaka Akiyama, Jumpei Morimoto, Shinsuke Sando   +8 more
wiley   +2 more sources

Pinoresinol enhances intestinal tight junction integrity via activation of the CaMKKβ-AMPKα1 pathway in Caco-2 cells. [PDF]

Genes Nutr
Shin SB, Kim YM, Park HY.
europepmc   +1 more source

Organic and inorganic selenium-enriched <i>Lactobacillus plantarum</i> differentially enhance bacterial antioxidant capacity and support redox homeostasis in intestinal Caco-2 cells through probiotic and postbiotic effects. [PDF]

Front Nutr
García-Vara A, Titos-Zamora M, Ferrer R, Martín-Venegas R.   +3 more
europepmc   +1 more source