Results 171 to 180 of about 52,118 (265)

Modulation of the Antioxidant System of Caco-2 Cells in the Presence of Aflatoxin B1, Ochratoxin A, and Ferulic Acid. [PDF]

Toxins (Basel)
Rădulescu AL, Popescu RG, Balas M, Marinescu GC, Dinischiotu A.   +4 more
europepmc   +1 more source

Synthesis of 4‐Hydroxyacetophenone‐Derived Bis‐Schiff Bases as Potent Cholinesterase Inhibitors: In Vitro Evaluation, Molecular Docking, DFT, and ADMET Analysis

Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.
A series of 4‐hydroxyacetophenone‐based bis‐Schiff bases were synthesized as dual cholinesterase inhibitors. Compound 2i showed the highest AChE and BuChE inhibition, supported by molecular docking, DFT, QTAIM, and ADMET studies. SAR analysis revealed the role of methoxy substitution in enhancing activity, highlighting 2i as a promising lead candidate ...
Muhammad Daud, Zainab Zainab, Aftab Alam, Imtiaz Ahmad, Ahmed A. Elhenawy, Abdul Latif, Mumtaz Ali, Syed Adnan Ali Shah, Syahrul Imran, Ashwag S. Alanazi, Mohammed M. Alanazi, Manzoor Ahmad   +11 more
wiley   +1 more source

Inhibitory Effect of <i>Boesenbergia rotunda</i> and Its Major Flavonoids, Pinostrobin and Pinocembrin on Carbohydrate Digestive Enzymes and Intestinal Glucose Transport in Caco-2 Cells. [PDF]

Int J Mol Sci
Aimjongjun S, Khamto N, Buangamdee V, Sornda T, Srivilai J, Limpeanchob N.   +5 more
europepmc   +1 more source

Berberine Inhibited Tumor Growth Through Suppressing the WDR54/β‐catenin Signal Pathway in Colorectal Cancer

Cell Biology International, Volume 50, Issue 8, August 2026.
ABSTRACT Berberine (BBR), a natural alkaloid, exhibits potent anti‐tumor activity in colorectal cancer (CRC), but its mechanisms are not fully elucidated. Analysis of GEO datasets (GSE216908 and GSE184414) identified WDR54 as a key target of BBR treatment. In vitro, BBR treatment of CRC cell lines (HT‐29 and SW480) markedly inhibited cell proliferation,
Qin Chen, Qi Chen, Fenqiong Tang
wiley   +1 more source

Listeria monocytogenes infection in intestinal epithelial Caco-2 cells with exposure to progesterone and estradiol-17beta. [PDF]

PLoS One
Hugon AM, Golos TG.
europepmc   +1 more source

Development of plant‐derived biomimetic nanoparticles as a novel targeted drug delivery platform

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Plant‐derived biomimetic nanoparticles (PD‐BNPs) represent a sustainable and biocompatible nanoplatform for targeted drug delivery. This review highlights their therapeutic potential, engineering strategies, and translational challenges toward precision nanomedicine applications. Abstract Plant‐derived biomimetic nanoparticles (PD‐BNPs) have emerged as
Jihad Hasan, Asnaf Nihan Shuvo, Md. Rezaul Karim Sheikh, A. Nayeem Faruqui   +3 more
wiley   +1 more source

Upcycled Green Coffee Phenolic-Rich Extract Modulates Key Pathways of Glucose Absorption in Caco-2 Cells: Findings From a Screening of Upcycled Agro-Industrial By-Products for Application in Functional Foods. [PDF]

Mol Nutr Food Res
Costa NA, Chiocchetti GME, de Godoy MCX, Gambero A, Macedo GA, Macedo JA.   +5 more
europepmc   +1 more source

Effects of Lactobacillus‐Mediated Functionalization of Dendrobium officinale Polysaccharides: A Study From Physicochemical Properties and Structural Changes to Anti‐Inflammatory Activity

eFood, Volume 7, Issue 4, August 2026.
Lactic acid bacteria (LAB) fermentation cleaves specific glycosidic bonds in Dendrobium officinale polysaccharides (DOPs), reducing molecular weight and enhancing anti‐inflammatory activity through regulation of inflammatory cytokines, oxidative stress, and intestinal barrier function.
Dingding Hong, Hui Ye, Xiaojun Huang
wiley   +1 more source

Methylomic Signature and Epigenetic Damage Modulation of Bronte Pistachio (<i>Pistacia vera</i> L.) Hydrophilic Extract in Differentiated CaCo-2 Cells. [PDF]

Nutrients
Cruciata I, Naselli F, Volpes S, Cardinale PS, Greco L, Martinelli F, Ramazzotti M, Perrone A, Serio G, Gentile C, Caradonna F.   +10 more
europepmc   +1 more source

Pulsed Electric Field Processing Enhances the Endothelial Bioefficacy of Red Beet (Beta vulgaris L.) Extracts by Restoring Endothelial Nitric Oxide Synthase–Nitric Oxide Signaling in High‐Fat Diet Rats

eFood, Volume 7, Issue 4, August 2026.
Pulsed electric field (PEF) processing qualitatively reshapes the phytochemical profile of red beet extracts, resulting in enhanced endothelial bioefficacy. Compared with conventional extraction, PEF‐treated extracts more effectively restore nitric oxide signaling, suppress endothelial inflammation, and normalize vascular structure in high‐fat diet ...
Eunju Jang, Tae‐Baek Lee, Lisa Tonini, Soobin Choi, YoonA Jeon, Taehyun Kim, Taeyoung Kang, Hyuk‐Joon Choi, Changhwan Ahn   +8 more
wiley   +1 more source