Results 191 to 200 of about 52,118 (265)

Oxyberberine alleviates lipopolysaccharide-induced intestinal barrier disruption and inflammation in human colonic Caco-2 cells in vitro. [PDF]

Front Pharmacol
Li C, Wang J, Yang H, Luo S, Lu Q.
europepmc   +1 more source

Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković, Strahinja Pešić, Marija Novaković, Anđela Dubroja Krstić, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source

Bioaccessible Bread Melanoidins Modulate Oxidative Stress, Reduce Inflammation and Suppress Adhesion of Helicobacter pylori to Caco-2 Cells. [PDF]

Nutrients
Gerardi G, Temiño V, Salazar-Mardones G, Díaz-Morales N, Melero B, Bocigas C, Muñiz P, Rovira J, Cavia-Saiz M.   +8 more
europepmc   +1 more source

Sevoflurane Alleviates Myocardial Ischemia‐Reperfusion Injury via the HMGB1/ACSL4 Pathway to Suppress Ferroptosis

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Sevoflurane (sevo) alleviates ferroptosis in cardiomyocytes and ameliorates MI/RI symptoms by inhibiting HMGB1 expression, reducing ACSL4 stability, and negatively regulating the HMGB1/ACSL4 signaling pathway. ABSTRACT Sevoflurane (sevo) exhibits cardioprotective effects against myocardial ischemia/reperfusion injury (MIRI); however, its precise ...
Yuliu Mei, Yunfei Cao, Cheng Sheng, Ge Sun, Manhua Zhu   +4 more
wiley   +1 more source

Antioxidant and Anti-Inflammatory Activity of a New Formulation of Slow-Release Amino Acids in Human Intestinal Caco-2 Cells. [PDF]

Antioxidants (Basel)
Bollati C, Tosi M, d'Adduzio L, Fanzaga M, Burlina A, Zuccotti G, Lammi C, Verduci E.   +7 more
europepmc   +1 more source

Monitoring the Effect of Tributyltin Salicylate and Propionate, Retinoid X Receptor Ligands, on Heat Shock Protein Expression in MDA‐MB‐231 Cells by MALDI MS/MS

Journal of Mass Spectrometry, Volume 61, Issue 8, August 2026.
ABSTRACT Organotin (IV) compounds are known to induce apoptosis via the intrinsic mitochondrial pathway, which is a key mechanism of effective anticancer therapy. Their ability to selectively promote apoptotic cell death highlights their potential as chemotherapeutic agents. In this study, the in vitro effects of two triorganotin compounds, tributyltin
Dana Strouhalova, Dana Macejova, Julius Brtko, Janette Bobalova   +3 more
wiley   +1 more source

Cannabidiol Enhances Mitochondrial Metabolism and Antioxidant Defenses in Human Intestinal Epithelial Caco-2 Cells. [PDF]

Nutrients
Bravo Iniguez A, Sun Q, Cui Q, Du M, Zhu MJ.   +4 more
europepmc   +1 more source

Raman Line Scan Analyses and a New Hypothesis for the Formation of Anatase‐Hosting Microbialites: Study of the Stromatolites From Saint‐Jean‐de‐la‐Rivière, Cotentin, France

Journal of Raman Spectroscopy, Volume 57, Issue 8, Page 1463-1480, August 2026.
Micrometer analysis of millimeter lines of Raman spectra concludes in the association of anatase and graphitized organic matter (graphogen). The photosynthetic microorganisms at the origin of the microbialites produce O2, which is transformed by TiO2 into reactive species that, in turn, decompose the organic matter of the microorganisms. ABSTRACT Raman
Marie‐Paule Bassez
wiley   +1 more source

Establishment of an in-vitro inflammatory bowel disease model using immunological differentiation of Caco-2 cells. [PDF]

MethodsX
Uemura I, Takahashi-Suzuki N, Kita F, Satoh T.   +3 more
europepmc   +1 more source

EphA2/SHP2/SOX8 Axis: A Novel Target for Regulation of Migration and Cetuximab Treatment Sensitivity in Oral Squamous Cell Carcinoma

Molecular Carcinogenesis, Volume 65, Issue 8, Page 977-988, August 2026.
ABSTRACT The development of resistance to anticancer therapies in cancer cell is a major challenge in the treatment of oral squamous cell carcinoma (OSCC), a common malignant tumor. Erythropoietin‐producing hepatocellular A2 (EphA2) affects several cancers, and this study examined its role in enhancing OSCC.
Dayong Yan, Lele Guo, Fei Pei, Ketao Zhong   +3 more
wiley   +1 more source