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Methylomic Signature and Epigenetic Damage Modulation of Bronte Pistachio (<i>Pistacia vera</i> L.) Hydrophilic Extract in Differentiated CaCo-2 Cells. [PDF]

open access: yesNutrients
Cruciata I   +10 more
europepmc   +1 more source
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Good Caco-2 Cell Culture Practices

Toxicology in Vitro, 2012
The human Caco-2 cells differentiate spontaneously in culture forming monolayers of mature intestinal enterocytes which have been used as a model of the intestinal barrier for in vitro toxicology studies. Reproducibility problems often reported in literature have been generally ascribed to different culture-related conditions, such as the type of ...
Armando Felsani, Igea D'Agnano
exaly   +5 more sources

Manganese transport by caco-2 cells

Biological Trace Element Research, 1999
The uptake and transport kinetics of manganese (Mn) were investigated in the human intestinal Caco-2 cell line both from the absorption side (apical to basolateral) and from the exsorption side (basolateral to apical). With regard to the former, transport versus time revealed (as uptake) a biphasic pattern with an initial transient phase followed by ...
G, Leblondel, P, Allain
openaire   +2 more sources

Caco‐2 Cells as a Model for Intestinal Absorption

Current Protocols in Toxicology, 2011
AbstractThe Caco‐2 cell system, a well characterized intestinal in vitro model, makes it possible to evaluate the ability of chemicals to cross the intestinal barrier, as well as to study their transport mechanisms. Permeability values estimated with this model correlate well with human in vivo absorption data for many drugs and chemicals.
Isabella De, Angelis, Laura, Turco
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Endogenous lipase activity in Caco-2 cells

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1998
Dietary triglycerides, the major precursors of long chain fatty acids (FA), require hydrolysis by pancreatic enzymes prior to their absorption by the small intestine. Although Caco-2 cells are frequently employed for the study of enterocyte lipid metabolism, the presence of an endogenous lipase activity has never been previously reported.
J H, Spalinger   +3 more
openaire   +2 more sources

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