Modulation of the Antioxidant System of Caco-2 Cells in the Presence of Aflatoxin B1, Ochratoxin A, and Ferulic Acid. [PDF]
Rădulescu AL +4 more
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Listeria monocytogenes infection in intestinal epithelial Caco-2 cells with exposure to progesterone and estradiol-17beta. [PDF]
Hugon AM, Golos TG.
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Inhibitory Effect of <i>Boesenbergia rotunda</i> and Its Major Flavonoids, Pinostrobin and Pinocembrin on Carbohydrate Digestive Enzymes and Intestinal Glucose Transport in Caco-2 Cells. [PDF]
Aimjongjun S +5 more
europepmc +1 more source
Purple Potato Extract Suppresses Hypoxia-Induced Metabolic Reprogramming and Inhibits HIF-1α Signaling in Caco-2 Cells. [PDF]
Cui Q +5 more
europepmc +1 more source
Methylomic Signature and Epigenetic Damage Modulation of Bronte Pistachio (<i>Pistacia vera</i> L.) Hydrophilic Extract in Differentiated CaCo-2 Cells. [PDF]
Cruciata I +10 more
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Good Caco-2 Cell Culture Practices
Toxicology in Vitro, 2012The human Caco-2 cells differentiate spontaneously in culture forming monolayers of mature intestinal enterocytes which have been used as a model of the intestinal barrier for in vitro toxicology studies. Reproducibility problems often reported in literature have been generally ascribed to different culture-related conditions, such as the type of ...
Armando Felsani, Igea D'Agnano
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Manganese transport by caco-2 cells
Biological Trace Element Research, 1999The uptake and transport kinetics of manganese (Mn) were investigated in the human intestinal Caco-2 cell line both from the absorption side (apical to basolateral) and from the exsorption side (basolateral to apical). With regard to the former, transport versus time revealed (as uptake) a biphasic pattern with an initial transient phase followed by ...
G, Leblondel, P, Allain
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Caco‐2 Cells as a Model for Intestinal Absorption
Current Protocols in Toxicology, 2011AbstractThe Caco‐2 cell system, a well characterized intestinal in vitro model, makes it possible to evaluate the ability of chemicals to cross the intestinal barrier, as well as to study their transport mechanisms. Permeability values estimated with this model correlate well with human in vivo absorption data for many drugs and chemicals.
Isabella De, Angelis, Laura, Turco
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Endogenous lipase activity in Caco-2 cells
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1998Dietary triglycerides, the major precursors of long chain fatty acids (FA), require hydrolysis by pancreatic enzymes prior to their absorption by the small intestine. Although Caco-2 cells are frequently employed for the study of enterocyte lipid metabolism, the presence of an endogenous lipase activity has never been previously reported.
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