Results 61 to 70 of about 52,118 (265)
Neoplasia: An International Journal for Oncology Research, 2009 In colorectal cancer, BRAF and KRAS oncogenes are mutated in about 15% and 35% respectively at approximately the same stage of the adenoma-carcinoma sequence.
Eftychia Oikonomou +5 more
doaj +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT The intestinal epithelium and its resident microbiota form a dynamic interface that is central to gut homeostasis, but this interface is difficult to model with conventional tools. Static Transwell cultures lack physiological fluid shear, whereas animal models are costly and poorly suited to quantitative, high‐content imaging.
Shih‐Wei Chiang +2 more
wiley +1 more source
Caveolin is present in intestinal cells: role in cholesterol trafficking?
Journal of Lipid Research, 1998 It was postulated that specialized microdomains of the plasma membrane, consistent with caveolae, might play a role in cholesterol trafficking in intestinal cells.
F. Jeffrey Field +3 more
doaj +1 more source
Key Challenges for Commercializing Perovskite–Silicon Tandem Solar Cells
Carbon Energy, EarlyView.This review discusses the scientific and technological challenges in advancing perovskite–silicon tandem solar cells (PSTSCs) from lab‐scale to commercial viability, focusing on long‐term stability, scalability, and economic feasibility. Key issues include intrinsic and extrinsic degradation factors, installation conditions, environmental impacts, and ...
Bilal Mehmood +16 more
wiley +1 more source
Differential miRNA-Gene Expression in M Cells in Response to Crohn’s Disease-Associated AIEC
Microorganisms, 2020 Adherent-invasive Escherichia coli (AIEC), which abnormally colonize the ileal mucosa of Crohn’s disease (CD) patients, are able to invade intestinal epithelial cells (IECs) and translocate through M cells overlying Peyer’s patches.
Anaïs Larabi +6 more
doaj +1 more source
Bacampicillin Uptake Is Shared with Thiamine in Caco-2 Cells
Biological and Pharmaceutical Bulletin, 2007 Bacampicillin was developed as a prodrug to improve the intestinal absorption of its metabolite ampicillin. This study was undertaken to characterize bacampicillin transport in Caco-2 cells. The uptake of bacampicillin in Caco-2 cells was significantly greater than those of ampicillin and pivampicillin.
Oda, Masako +3 more
openaire +3 more sources
In Vitro Activity of Citrus IntegroPectin Against Breast Cancer and Colon Cancer
ChemFoodChem, EarlyView.Image shows microscopic photographs of MCF‐7 cells in the presence of lemon, red orange, and sweet orange IntegroPectin bioconjugates at 0.5 or 1.0 mg/mL concentration after 24 h next to a photograph of MCF‐7 cells as such (control). ABSTRACT We investigate the ability of IntegroPectin bioconjugates obtained via acoustic cavitation of lemon, red orange,
Claudia D'Anna +5 more
wiley +1 more source
High‐Pressure Na‐Ca Carbonates in the Deep Carbon Cycle
Geophysical Monograph Series, Page 127-136., 2020 This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Sergey Rashchenko +2 more
wiley +3 more sources
Toxicity of CdSe Nanoparticles in Caco-2 Cell Cultures
Journal of Nanobiotechnology, 2008 Abstract Background Potential routes of nanomaterial exposure include inhalation, dermal contact, and ingestion. Toxicology of inhalation of ultra-fine particles has been extensively studied; however, risks of nanomaterial exposure via ingestion are currently almost unknown.
Dokmeci Mehmet R +4 more
openaire +3 more sources
Clinical Pharmacology &Therapeutics, EarlyView.Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang +2 more
wiley +1 more source