Results 21 to 30 of about 3,724 (147)

Neurological and systemic manifestations of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL): a nationwide study in Korea [PDF]

Alzheimers Dement
Abstract Background This study investigated the epidemiological and clinical features of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) in South Korea, comparing patients to age‐ and sex‐matched controls.
Jung Y.
europepmc   +2 more sources

Is the oxidant/antioxidant status altered in CADASIL patients?

PLoS ONE, 2013
The altered aggregation of proteins in non-native conformation is associated with endoplasmic reticulum derangements, mitochondrial dysfunction and excessive production of reactive oxygen species. Cerebral autosomal dominant arteriopathy with subcortical
Jonica Campolo, Renata De Maria, Caterina Mariotti, Chiara Tomasello, Marina Parolini, Marina Frontali, Domenico Inzitari, Raffaella Valenti, Antonio Federico, Franco Taroni, Oberdan Parodi   +10 more
doaj   +1 more source

CADASIL Argentine Registry: Study Design and Preliminary Data [PDF]

Alzheimers Dement
Abstract Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), the most common hereditary small vessel disease, leads to early‐onset stroke and vascular cognitive impairment (VCI). Despite its importance, data from Latin America remain scarce.
Cristalli C, Rosales J, Gonzalez F, Selvaggi V, Alonso J, López J, Aguilar M, Kauffman M, Saks D, Allegri R, Sevlever G, Chaves H, Cristalli D, Calandri I.   +13 more
europepmc   +2 more sources

Intracranial Large Artery Abnormalities and Association With Cerebral Small Vessel Disease in CADASIL

Frontiers in Neurology, 2020
Background and objective: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited systemic arteriopathy, the classic feature of which is small vessel lesions.
Chen Zhang, Wei Li, ShaoWu Li, SongTao Niu, XinGao Wang, Xueying Yu, ZaiQiang Zhang   +6 more
doaj   +1 more source

Lifelong cerebrovascular disease burden among CADASIL patients: analysis from a global health research network

Frontiers in Neurology, 2023
IntroductionData reporting on patients with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) within the United States population is limited.
Alan P. Pan, Thomas Potter, Abdulaziz Bako, Jonika Tannous, Sudha Seshadri, Louise D. McCullough, Farhaan S. Vahidy, Farhaan S. Vahidy, Farhaan S. Vahidy   +8 more
doaj   +1 more source

CADASIL Syndrome Presenting as Adjustment Disorder

İstanbul Medical Journal, 2020
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), usually referred to as CADASIL, is an inherited autosomal dominant condition that can cause stroke, dementia and other neurological impairments ...
Sevda Bağ, Pelin Özkara, Evrim Erten
doaj   +1 more source

Investigating the effects of NOTCH3 Asian‐specific mutant on blood‐brain‐barrier using patient iPSC‐derived cell types [PDF]

Alzheimers Dement
Abstract Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), is the genetic form of vascular dementia leading to vascular impairments and cognitive decline. CADASIL is caused by mutations in the NOTCH3 gene which encodes a single‐pass transmembrane receptor. The NOTCH3 mutant (MT) is reported
Lee J, Ng A, Tan E, Zeng L.
europepmc   +2 more sources

Lenticulostriate Arteries and Basal Ganglia Changes in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy, a High-Field MRI Study

Frontiers in Neurology, 2019
Background and Purpose: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) mainly affects the cerebral small arteries.
Chen Ling, Xiaojing Fang, Xiaojing Fang, Qingle Kong, Qingle Kong, Qingle Kong, Yunchuang Sun, Bo Wang, Bo Wang, Bo Wang, Yan Zhuo, Yan Zhuo, Yan Zhuo, Jing An, Wei Zhang, Zhaoxia Wang, Zihao Zhang, Zihao Zhang, Zihao Zhang, Yun Yuan   +19 more
doaj   +1 more source

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL): Three case reports from Serbia [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2008
Introduction Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary microangiopathy leading to recurrent strokes and vascular dementia in young and middleaged patients.
Zidverc-Trajković Jasna, Lačković Vesna, Pavlović Aleksandra, Bajčetić Miloš, Carević Zvonko, Tomić Gordana, Mandić Gorana, Mijajlović Milija, Jovanović Zagorka, Šternić Nadežda   +9 more
doaj   +1 more source

Insulin-Independent and Dependent Glucose Transporters in Brain Mural Cells in CADASIL

Frontiers in Genetics, 2020
Typical cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by mutations in the human NOTCH3 gene.
Mahmod Panahi, Patricia Rodriguez Rodriguez, Seyed-Mohammad Fereshtehnejad, Seyed-Mohammad Fereshtehnejad, Donia Arafa, Nenad Bogdanovic, Nenad Bogdanovic, Bengt Winblad, Angel Cedazo-Minguez, Juha Rinne, Taher Darreh-Shori, Yoshiki Hase, Raj N. Kalaria, Matti Viitanen, Matti Viitanen, Homira Behbahani   +15 more
doaj   +1 more source