Results 121 to 130 of about 284,314 (352)

Supplemental Material, Supp_files - Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin

, 2018
Supplemental Material, Supp_files for Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin by Joseph W Po, Aflah Roohullah, David Lynch, Anna DeFazio, Michelle Harrison, Paul R Harnett ...
Therese M Becker (5498255), Joseph W Po (5498252), Michelle Harrison (3347252), Catherine Kennedy (227468), Paul de Souza (585566), Paul R Harnett (5498246), Aflah Roohullah (5498249), David Lynch (3449231), Anna DeFazio (5498258)   +8 more
core   +1 more source

Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration

Cell, 2014
Summary E-cadherin is a major homophilic cell-cell adhesion molecule that inhibits motility of individual cells on matrix. However its contribution to migration of cells through cell-rich tissues is less clear.
Danfeng Cai, Shann-Ching Chen, Mohit Prasad, Li He, Xiaobo Wang, Valérie Choesmel-Cadamuro, Jessica K. Sawyer, G. Danuser, D. Montell   +8 more
semanticscholar   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Functional assessment of cadherin as a shared mechanism for cross/dual resistance to Cry1Ac and Cry2Ab in Helicoverpa zea

Journal of Integrative Agriculture
Helicoverpa zea is a major target pest of pyramided transgenic crops expressing Cry1, Cry2 and/or Vip3Aa proteins from Bacillus thuringiensis (Bt) in the United States.
Jizhen Wei, Min Zhang, Pin Li, Zhongyuan Deng, Xinming Yin, Shiheng An, Xianchun Li   +6 more
doaj   +1 more source

Structural determinants of adhesion by Protocadherin-19 and implications for its role in epilepsy

eLife, 2016
Non-clustered δ-protocadherins are homophilic cell adhesion molecules essential for the development of the vertebrate nervous system, as several are closely linked to neurodevelopmental disorders. Mutations in protocadherin-19 (PCDH19) result in a female-
Sharon R Cooper, James D Jontes, Marcos Sotomayor   +2 more
doaj   +1 more source

Comparison of E-cadherin and Beta-catenin Expression with Gleason Score and Other Prognostic Factors in Prostate Carcinomas

, 2020
Objectives:Cell adhesion complex E-cadherin and beta-catenin have important roles in tissue integrity, organization, protection of epithelial phenotype, transcription and proliferation of epithelial cells. Changes in these molecules have been reported in
Tolga Bağlan, Özlem Erdem
core   +1 more source

Matrix Stiffness Directs Stemness Signatures in Breast Cancer

Advanced Healthcare Materials, EarlyView.
We built lab‐grown breast cancer models to study how the stiffness of the tumor's surroundings influences cancer behavior. Softer environments encouraged more stem‐like, drug‐resistant cells, while stiffer ones kept cells more differentiated. These findings show that tissue mechanics drive cancer diversity and drug resistance, offering new insights for
Chantal Kopecky, Elvis Pandzic, Sean Porazinski, J Justin Gooding, Kristopher A Kilian   +4 more
wiley   +1 more source

Identification and characterisation of a novel integral membrane protein, shrew-1 that complexes with adherens junctions in polarised cells

, 2005
In an attempt to search for potential candidate molecules involved in the pathogenesis of endometriosis, a novel 2910 bp cDNA encoding a putative 411 amino acid protein, shrew-1 was discovered. By computational analysis it was predicted to be an integral
Bharti, Sanita
core  

Goblet cell metaplasia is associated with increased invasion and tumor aggression in E-cadherin-Pten bigenic knockout mouse prostates.

, 2019
A-C2’. H&E images of prostate tissue sections from Cdh1L/L:Pten L/L:PB-Cre4 mice between 15 & 20 months of age. D1-D6’. Representative images of goblet cell metaplasia using various stains as indicated. Arrows denote PAS positive goblet cells (D1’ and D2’
Dong-Hong Lee (6260738), Adam Olson (6260747), Yongfeng He (849499), Won Kyung Kim (7553153), Zijie Sun (20150), Vien Le (6260744), Robert D. Cardiff (144438), Joseph Geradts (65246), Eun-Jeong Yu (849498), Erika Hooker (849497), Joseph Aldahl (6260741)   +10 more
core   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source