Results 211 to 220 of about 305,587 (238)
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Cadherins in Cancer

2004
The presence of a functional E-cadherin/catenin cell-cell adhesion complex is a prerequisite for normal development and maintenance of epithelial structures in the mammalian body. This implies that the acquisition of molecular abnormalities that disturb the expression or function of this complex is related to the development and progression of most, if
F. Van Roy, Kristin Strumane, Geert Berx
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T‐Cadherin 2: Molecular characterization, function in cell adhesion, and coexpression with T‐cadherin and N‐cadherin

Journal of Neuroscience Research, 1993
AbstractCadherins are integral membrane glycoproteins that mediate calcium‐dependent, homophilic cell‐cell adhesion and are implicated in controlling tissue morphogenesis. T‐cadherin is anchored to the membrane through a glycosyl phosphatidylinositol (Ranscht B, Dours‐Zimmermann MT: Neuron 7:391–402, 1991) and expressed in a restricted pattern in ...
Sacrist?n Mart?n, Mar?a Paz   +3 more
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Cadherins in Development

2004
The cadherin family of cell adhesion molecules has emerged as a key regulator of embryonic morphogenesis. Although we are beginning to learn more about the developmental functions of non-classic cadherins, most of our current knowledge of the involvement of cadherins in various cellular processes that guide morphogenesis, such as adhesion, migration ...
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The Premetazoan Ancestry of Cadherins [PDF]

open access: possibleScience, 2008
Cadherin-mediated cell adhesion and signaling is essential for metazoan development and yet is absent from all other multicellular organisms. We found cadherin genes at numbers similar to those observed in complex metazoans in one of the closest single-celled relatives of metazoans, the choanoflagellate Monosiga brevicollis
Nicole King, Monika Abedin
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Cadherins and synaptic specificity

Journal of Neuroscience Research, 1999
Cadherins are a family of cell-cell adhesion molecules that regulate morphogenesis in a variety of organs during development. In this review, we summarize recent evidence that cadherins may be involved in synaptogenesis in the vertebrate central nervous system.
Kirstin Obst‐Pernberg   +1 more
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T‐cadherin in the mammalian cochlea

The Laryngoscope, 2011
AbstractObjectives/Hypothesis:Cadherins are a superfamily of transmembrane glycoproteins, which mediate calcium‐dependent intercellular adhesions. T‐cadherin is an atypical member of the cadherin family in regard to its structure; it acts as a signalling receptor rather than an adhesion molecule.
Listyo, A.   +6 more
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Classical cadherins

Seminars in Cell Biology, 1992
Cadherins represent a gene family of Ca(2+)-dependent cell adhesion molecules (CAMs) identified during development and in adult organs. They generally mediate cell-cell adhesion by homotypic interaction, although heterotypic binding between different cadherin molecules is possible.
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Fat and Dachsous Cadherins

2013
Fat and Dachsous (Ds) are very large cell adhesion molecules. They bind each other and have important, highly conserved roles in planar cell polarity (PCP) and growth control. PCP is defined as the directionally coordinated development of cellular structures or behavior.
Helen McNeill, Praveer P. Sharma
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Cadherins

Annual Review of Cell Biology, 1992
B, Geiger, O, Ayalon
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Cadherins in Cancer

2016
Despite decades of research, cancer remains one of the leading causes of death worldwide. Progression of cancer includes the breakdown or loss of normal tissue structure, which closely depends on the proper expression and regulation of numerous cell–cell adhesion molecules.
Kathleen J. Green   +3 more
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