Results 251 to 260 of about 215,865 (348)

Computational systems biology approaches to cellular aging—Integrating network maps and dynamical models

Quantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Cellular aging is a multifaceted complex process. Many genes and factors have been identified that regulate cellular aging. However, how these genes and factors interact with one another and how these interactions drive the aging processes in single cells remain largely unclear.
Hetian Su, Nan Hao
wiley   +1 more source

High‐Specificity Spatiotemporal Cholesterol Detection by Quadrature Phase‐Shifted Polarization Stimulated Raman Imaging

Angewandte Chemie, Volume 137, Issue 32, August 4, 2025.
Utilizing quadrature phase modulation, the phase‐shifted polarization SRS (QP2‐SRS) microscope enables simultaneous measurement of the ρ‐related χ1111(3)$\chi _{1111}^{( 3 )}$ and χ1221(3)$\chi _{1221}^{( 3 )}$ components. In cholesterol molecular measurements, QP2‐SRS leverages the structural differences between cholesterol and other biomolecules to ...
Yongqing Zhang, Xinyu Deng, Siming Wang, Wenyu Zhou, Zhengyan Wu, Xiaobin Tang, Hyeon Jeong Lee, Delong Zhang   +7 more
wiley   +2 more sources

Two New Cases Expand the Phenotypic Spectrum of TUBG1 Missense Variants

American Journal of Medical Genetics Part A, Volume 197, Issue 9, September 2025.
ABSTRACT The gamma‐tubulin ring complex (γ‐TuRC) plays a role in coordinating centrosome and spindle pole body formation during cell division. TUBG1 encodes a critical component of the γ‐TuRC. Pathogenic TUBG1 variants can cause a range of alterations in cortical gyral patterning, microcephaly, and other neurological manifestations.
Roser Urreizti, Jessica Vissicchio, Mohamed Idries, Monica Cozar, Raquel Rabionet, Tyhiesia Donald, Elizabeth J. Bhoj, Tomoki T. Nomakuchi, Shannon C. Shipley, Andrew E. Timms, Ghayda M. Mirzaa, Mercedes Serrano, Andrew K. Sobering   +12 more
wiley   +1 more source

A practical guide to ordering C. elegans strains for biological research. [PDF]

Mol Cells
Park YJ, Moon KM, Kim K.
europepmc   +1 more source

Genes critical for muscle development and function in Caenorhabditis elegans identified through lethal mutations

, 1994
BD Williams, RH Waterston
openalex   +1 more source

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

MedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava, Kalyani Eswar, Sasvat Sayee Ram Ramesh, Akshit Prajapati, Tanvi Sonpipare, Apoorva Basa, Mounika Gubige, Sribala Ponnapalli, Shashidhar Thatikonda, Aravind Kumar Rengan   +9 more
wiley   +1 more source

Anti-aging activities of an ethanolic extract of <i>Lycium ruthenicum</i> in <i>Caenorhabditis elegans</i> based on metabonomic analysis. [PDF]

Front Pharmacol
Cui B, Liu L, Qiao X, Shi T, Yin M, Xu S, Feng X, Shan Y.   +7 more
europepmc   +1 more source

In situ quantification of ribosome number by electron tomography

Journal of Microscopy, Volume 299, Issue 3, Page 212-227, September 2025.
Abstract Ribosomes, discovered in 1955 by George Palade, were initially described as small cytoplasmic particles preferentially associated with the endoplasmic reticulum (ER). Over the years, extensive research has focused on both the structure and function of ribosomes.
Mounir El Hankouri, Marco Nousch, Aayush Poddar, Thomas Müller‐Reichert, Gunar Fabig   +4 more
wiley   +1 more source

Velvety tree ant extract is a chemotaxis repellent for <i>C. elegans</i>. [PDF]

MicroPubl Biol
Gaerlan M, Carrillo M, Ceva S, Chundi S, Diallo B, Fong JN, Huang K, Jackson J, Padilla J, Quintana L, Santa Maria K, Sarkisian SM, Sequeira PR, Tatlock EU, Baker PR, Bachmann L, Park S, Perez MJ, Phipps ME, Sharma SN, Soto-Hernandez Y, Juarez BH, Mena C, Morales G, Gonzalez M, Fiocca K, Bradon N, Madrzyk M, O'Connell LA.   +28 more
europepmc   +1 more source

Functional study of Phaeodactylum tricornutum Seipin highlights specificities of lipid droplets biogenesis in diatoms

New Phytologist, Volume 247, Issue 5, Page 2245-2269, September 2025.
Summary Diatoms are a major phylum of microalgae, playing crucial ecological roles. They derive from secondary endosymbiosis, leading to a complex intracellular architecture. Their ability to store oil in lipid droplets (LDs) upon unfavourable conditions has raised interest for applications, in particular biofuels, yet Lipid Droplet (LD) biogenesis ...
Damien Le Moigne, Marta Carletti, Chems Amari, Rachel Bonnarde, Fabien Richard, Catherine Albrieux, Mégane Mahieu, Matteo Arrighi, Grégory Si‐Larbi, Pierre‐Henri Jouneau, Valérie Gros, Mathilde Louwagie, Sylvaine Roy, Yangmin Gong, Yufang Pan, Hanhua Hu, Olivier Bastien, Juliette Jouhet, Alberto Amato, Eric Maréchal, Juliette Salvaing   +20 more
wiley   +1 more source