Results 231 to 240 of about 193,403 (293)

The RNAi Inheritance Machinery of Caenorhabditis elegans

open access: yesGenetics, 2017
G. Spracklin   +6 more
semanticscholar   +1 more source

New insights into Sti1/Hop's cochaperone function highlight the complexity of proteostatic regulation

open access: yesThe FEBS Journal, EarlyView.
Sti1/Hop functions extend beyond scaffolding in the Hsp70‐Hsp90 chaperone complex to sequester misfolded proteins during cell stress. Consequently, imbalances between levels of Sti1/Hop relative to the rest of the proteostasis machinery negatively affect fitness and stress resilience. Sti1/Hop is a cochaperone that regulates Hsp70 and Hsp90 chaperones.
Gregory Lloyd Blatch   +1 more
wiley   +1 more source

The quest for the best target genes for RNAi‐mediated pest control

open access: yesInsect Molecular Biology, EarlyView.
A major challenge for RNAi mediated pest control is the identification of the most effective RNAi target genes from the pool of ~37% of all genes that are essential. Effective RNAi target genes are predominantly highly conserved genes serving basic cellular functions such as protein degradation.
Doga Cedden, Gregor Bucher
wiley   +1 more source

Understanding the genetics of sex determination in insects and its relevance to genetic pest management

open access: yesInsect Molecular Biology, Volume 34, Issue 3, Page 363-380, June 2025.
In insect sex determination pathways, the primary signals may vary within and between insect orders; however, the relay and terminal genes are more conserved. The upstream components of insect sex determination pathways ensure the downstream components are sex‐specifically spliced to regulate the development of male and female‐specific traits in a sex ...
Jade S. Ashmore   +3 more
wiley   +1 more source

Immunometabolism in Caenorhabditis elegans.

open access: yesPLoS Pathogens, 2020
Sarah M Anderson, Read Pukkila-Worley
doaj   +1 more source

In situ quantification of ribosome number by electron tomography

open access: yesJournal of Microscopy, EarlyView.
Abstract Ribosomes, discovered in 1955 by George Palade, were initially described as small cytoplasmic particles preferentially associated with the endoplasmic reticulum (ER). Over the years, extensive research has focused on both the structure and function of ribosomes.
Mounir El Hankouri   +4 more
wiley   +1 more source

From whole bodies to single cells: A guide to transcriptomic approaches for ecology and evolutionary biology

open access: yesMolecular Ecology, EarlyView.
Abstract RNA sequencing (RNAseq) methodology has experienced a burst of technological developments in the last decade, which has opened up opportunities for studying the mechanisms of adaptation to environmental factors at both the organismal and cellular level. Selecting the most suitable experimental approach for specific research questions and model
Katja M. Hoedjes   +19 more
wiley   +1 more source

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