Results 71 to 80 of about 279,189 (378)
A cell-specific enhancer that specifies lin-3 expression in the C. elegans anchor cell for vulval development [PDF]
, 2004 During C. elegans vulval development, the anchor cell (AC) in the somatic gonad expresses lin-3, activating the EGF receptor signaling pathway in vulval precursor cells (VPCs) and thereby inducing and patterning VPCs.
Hwang, Byung Joon, Sternberg, Paul W.
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OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes
Genetics, 2018 OrthoList, a compendium of Caenorhabditis elegans genes with human orthologs compiled in 2011 by a meta-analysis of four orthology-prediction methods, has been a popular tool for identifying conserved genes for research into biological and disease ...
Woojin Kim +3 more
semanticscholar +1 more source
Caenorhabditis elegans par genes [PDF]
Current Biology, 2002 What are they? Six par genes (par-1 through par-6) have been identified in Caenorhabditis elegans. Loss-of-function mutations in any par locus results in loss of anterior–posterior (AP) asymmetries during the first two embryonic cell divisions. This results in a failure to restrict developmental regulators to specific embryonic cells, mitotic spindle ...
José-Eduardo Gomes, Bruce Bowerman
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Binucleation ramps up gene expression meeting the physiological demands of an organism
PLoS Biology, 2022 In this issue of PLOS Biology, van Rijnberk and colleagues show how polyploidy, via binucleation, enables Caenorhabditis elegans intestinal cells to ramp up gene expression supplying the oocytes with the necessary lipids for optimal organismal growth and
Ari S. Dehn, Vicki P. Losick
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A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans [PDF]
, 2004 Molting is required for progression between larval stages in the life cycle of nematodes. We have identified four mutant alleles of a <i>Caenorhabditis elegans</i> metalloprotease gene, <i>nas-37</i>, that cause incomplete ...
Birnie, A.J. +4 more
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Age‐dependent changes and biomarkers of aging in Caenorhabditis elegans
Aging Cell, 2019 Caenorhabditis elegans is an exceptionally valuable model for aging research because of many advantages, including its genetic tractability, short lifespan, and clear age‐dependent physiological changes. Aged C.
H. Son +4 more
semanticscholar +1 more source
Optogenetic mutagenesis in Caenorhabditis elegans [PDF]
Nature Communications, 2015 AbstractReactive oxygen species (ROS) can modify and damage DNA. Here we report an optogenetic mutagenesis approach that is free of toxic chemicals and easy to perform by taking advantage of a genetically encoded ROS generator. This method relies on the potency of ROS generation by His-mSOG, the mini singlet oxygen generator, miniSOG, fused to a ...
Noma, Kentaro, Jin, Yishi
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Advanced Biology, EarlyView.The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez +8 more
wiley +1 more source
Prereplication complex proteins get caught moonlighting
PLoS Biology, 2022 In this issue of PLOS Biology, Lattmann and colleagues report a new function for proteins of the DNA prereplication complex promoting the anchor cell to invade through the basement membrane and initiate vulval development in Caenorhabditis elegans.
Hilary A. Coller
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Wormwholes: A Commentary On K.F. Schaffer\u27s Genes, Behavior, And Developmental Emergentism [PDF]
, 1998 Although Caenorhabditis elegans was chosen and modified to be an organism that would facilitate a reductionist program for neurogenetics, recent research has provided evidence for properties that are emergent from the neurons. While neurogenetic advances
Gilbert, Scott F., Jorgensen, E. M.
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