Results 81 to 90 of about 279,189 (378)

The Caenorhabditis elegans Transgenic Toolbox

Genetics, 2019
The power of any genetic model organism is derived, in part, from the ease with which gene expression can be manipulated. The short generation time and invariant developmental lineage have made Caenorhabditis elegans very useful for understanding, e.g ...
Jeremy Nance, Christian Frøkjær-Jensen
semanticscholar   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source

Intermediary metabolism [PDF]

, 2009
Caenorhabditis elegans has orthologs for most of the key enzymes involved in eukaryotic intermediary metabolism, suggesting that the major metabolic pathways are probably present in this species.
Braeckman, Bart, Houthoofd, Koen, Vanfleteren, Jacques   +2 more
core   +2 more sources

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Nematophagous fungus Arthrobotrys oligospora mimics olfactory cues of sex and food to lure its nematode prey

eLife, 2017
To study the molecular basis for predator-prey coevolution, we investigated how Caenorhabditis elegans responds to the predatory fungus Arthrobotrys oligospora. C. elegans and other nematodes were attracted to volatile compounds produced by A. oligospora.
Yen-Ping Hsueh, Matthew R Gronquist, Erich M Schwarz, Ravi David Nath, Ching-Han Lee, Shalha Gharib, Frank C Schroeder, Paul W Sternberg   +7 more
doaj   +1 more source

Distinct roles of transcription factors EGL-46 and DAF-19 in specifying the functionality of a polycystin-expressing sensory neuron necessary for C. elegans male vulva location behavior [PDF]

, 2003
Caenorhabditis elegans polycystins LOV-1 and PKD-2 are expressed in the male-specific HOB neuron, and are necessary for sensation of the hermaphrodite vulva during mating. We demonstrate that male vulva location behavior and expression of lov-1 and pkd-2
Bürglin, Thomas R., Prétôt, René F., Sternberg, Paul W., Yu, Hui   +3 more
core   +1 more source

The Multilayer Connectome of Caenorhabditis elegans

PLOS Computational Biology, 2016
Connectomics has focused primarily on the mapping of synaptic links in the brain; yet it is well established that extrasynaptic volume transmission, especially via monoamines and neuropeptides, is also critical to brain function and occurs primarily outside the synaptic connectome.
Bentley, Barry, Branicky, Robyn, Barnes, Christopher L, Chew, Yee Lian, Yemini, Eviatar, Bullmore, Edward T, Vértes, Petra E, Schafer, William R   +7 more
openaire   +9 more sources

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

Label-free three-dimensional imaging of Caenorhabditis elegans with visible optical coherence microscopy. [PDF]

PLoS ONE, 2017
Fast, label-free, high-resolution, three-dimensional imaging platforms are crucial for high-throughput in vivo time-lapse studies of the anatomy of Caenorhabditis elegans, one of the most commonly used model organisms in biomedical research.
Séverine Coquoz, Paul J Marchand, Arno Bouwens, Laurent Mouchiroud, Vincenzo Sorrentino, Daniel Szlag, Johan Auwerx, Theo Lasser   +7 more
doaj   +1 more source

WormBase: a multi-species resource for nematode biology and genomics [PDF]

, 2004
WormBase (http://www.wormbase.org/) is the central data repository for information about Caenorhabditis elegans and related nematodes. As a model organism database, WormBase extends beyond the genomic sequence, integrating experimental results with ...
Antoshechkin, Igor, Bastiani, Carol, Bieri, Tamberlyn, Blasiar, Darin, Bradnam, Keith, Chan, Juancarlos, Chen, Chao-Kung, Chen, Nansheng, Chen, Wen J., Cunningham, Fiona, Davis, Paul, Durbin, Richard, Harris, Todd W., Kenny, Eimear, Kishore, Ranjana, Lawson, Daniel, Lee, Raymond Y. N., Müller, Hans-Michael, Nakamura, Cecilia, Ozersky, Philip, Petcherski, Andrei, Rogers, Anthony, Sabo, Aniko, Schwarz, Erich M., Spieth, John, Stein, Lincoln D., Sternberg, Paul W., Tello-Ruiz, Marcela, Van Auken, Kimberly, Wang, Qinghua   +29 more
core   +3 more sources