Results 81 to 90 of about 193,403 (293)

A cell-specific enhancer that specifies lin-3 expression in the C. elegans anchor cell for vulval development [PDF]

, 2004
During C. elegans vulval development, the anchor cell (AC) in the somatic gonad expresses lin-3, activating the EGF receptor signaling pathway in vulval precursor cells (VPCs) and thereby inducing and patterning VPCs.
Hwang, Byung Joon, Sternberg, Paul W.
core   +1 more source

Sugar‐sensing swodkoreceptors and swodkocrine signaling

Animal Models and Experimental Medicine, EarlyView.
Sugar‐sensing swodkoreceptors that trigger swodkocrine signaling. Abstract Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production. In addition, sugars can act as signaling molecules. To study sugar signaling at the systemic level, there is an urgent need to systematically identify sugar‐sensing ...
Savani Anbalagan
wiley   +1 more source

The Natural Biotic Environment of Caenorhabditis elegans

Genetics, 2017
Organisms evolve in response to their natural environment. Consideration of natural ecological parameters are thus of key importance for our understanding of an organism’s biology.
H. Schulenburg, M. Félix
semanticscholar   +1 more source

Advanced Contactless Bioassembly Approaches: Leveraging Sound, Optical, and Magnetic Fields

Advanced NanoBiomed Research, EarlyView.
This review explores innovative contactless bioassembly techniques driven by sound, light, and magnetic fields, which enable the precise organization of cells, biomaterials, and bioactive substances into complex 3D structures. These technologies, crucial for in vitro modeling and regenerative medicine, are examined in detail, highlighting their ...
Micaela Natta, Greta Cocchi, Riccardo Tognato, Alessandro Cianciosi, Tiziano Serra   +4 more
wiley   +1 more source

Progress in Biomimetic Microdevices for Anticancer Drug Screening and their Potential for Enhancing In Vivo Efficacy

Advanced NanoBiomed Research, EarlyView.
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo, Yen‐Tzu Liao, Hsinyu Lee   +2 more
wiley   +1 more source

Imaging the Pharynx to Measure the Uptake of Doxorubicin in Caenorhabditis elegans

Bio-Protocol, 2017
Caenorhabditis elegans offers an array of advantages to investigate the roles of uptake transporters. Herein, an epifluorescent microscopy approach was developed to monitor the uptake of the autofluorescent anticancer drug, doxorubicin, into the pharynx ...
Sivathevy Amirthagunabalasingam, Arturo Papaluca, Taramatti Harihar, Dindial Ramotar   +3 more
doaj   +1 more source

Histone deacetylase HDA-1 modulates mitochondrial stress response and longevity

Nature Communications, 2020
Caenorhabditis elegans responds to mitochondrial stress by activating the mitochondrial unfolded protein response (UPRmt). Here the authors show that HDA-1, the C.
Li-Wa Shao, Qi Peng, Mingyue Dong, Kaiyu Gao, Yumei Li, Yi Li, Chuan-Yun Li, Ying Liu   +7 more
doaj   +1 more source

The Multilayer Connectome of Caenorhabditis elegans [PDF]

PLoS Comput. Biol., 2016
Connectomics has focused primarily on the mapping of synaptic links in the brain; yet it is well established that extrasynaptic volume transmission, especially via monoamines and neuropeptides, is also critical to brain function and occurs primarily ...
Barry L. Bentley, Robyn Branicky, Christopher L. Barnes, Yee Lian Chew, Ev Yemini, E. Bullmore, P. Vértes, W. Schafer   +7 more
semanticscholar   +1 more source

WormBase: a multi-species resource for nematode biology and genomics [PDF]

, 2004
WormBase (http://www.wormbase.org/) is the central data repository for information about Caenorhabditis elegans and related nematodes. As a model organism database, WormBase extends beyond the genomic sequence, integrating experimental results with ...
Antoshechkin, Igor, Bastiani, Carol, Bieri, Tamberlyn, Blasiar, Darin, Bradnam, Keith, Chan, Juancarlos, Chen, Chao-Kung, Chen, Nansheng, Chen, Wen J., Cunningham, Fiona, Davis, Paul, Durbin, Richard, Harris, Todd W., Kenny, Eimear, Kishore, Ranjana, Lawson, Daniel, Lee, Raymond Y. N., Müller, Hans-Michael, Nakamura, Cecilia, Ozersky, Philip, Petcherski, Andrei, Rogers, Anthony, Sabo, Aniko, Schwarz, Erich M., Spieth, John, Stein, Lincoln D., Sternberg, Paul W., Tello-Ruiz, Marcela, Van Auken, Kimberly, Wang, Qinghua   +29 more
core   +3 more sources

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source