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Nuclear/Cytoplasmic Fractionation of Proteins from Caenorhabditis elegans [PDF]

open access: greenBio-Protocol, 2018
C. elegans is widely used to investigate biological processes related to health and disease. To study protein localization, fluorescently-tagged proteins can be used in vivo or immunohistochemistry can be performed in whole worms.
Alejandro Mata-Cabana   +3 more
doaj   +8 more sources

An SRR1 domain-containing protein is required for efficient Orsay virus replication in Caenorhabditis elegans [PDF]

open access: yesJournal of Virology
Viruses depend on their hosts for completing their life cycle, and a better understanding of virus replication can inform therapeutic strategies. Using the Orsay virus-Caenorhabditis elegans experimental platform, we identified by a forward genetic ...
Chika Fujii, David Wang
doaj   +2 more sources

Kinesins in Caenorhabditis elegans neuronal morphogenesis [PDF]

open access: yesOpen Biology
Neuronal morphogenesis is regulated by intracellular transport and cytoskeletal dynamics. Kinesin superfamily proteins (KIFs), or kinesins, function as molecular motors for intracellular transport and as regulators of the microtubule cytoskeleton, making
Shinsuke Niwa, Kyoko Chiba
doaj   +2 more sources

Recent progress in regulation of aging by non-coding RNAs in Caenorhabditis elegans [PDF]

open access: yesAnimal Cells and Systems
Non-coding RNAs (ncRNAs) are RNA molecules that are not translated into proteins. Recent advances in RNA biology have uncovered roles of ncRNAs in physiological processes, including aging.
Seungjae Hwang   +2 more
doaj   +2 more sources

Prereplication complex proteins get caught moonlighting

open access: yesPLoS Biology, 2022
In this issue of PLOS Biology, Lattmann and colleagues report a new function for proteins of the DNA prereplication complex promoting the anchor cell to invade through the basement membrane and initiate vulval development in Caenorhabditis elegans.
Hilary A. Coller
doaj   +3 more sources

Identification and Functional Analysis of Cytokine-Like Protein CLEC-47 in Caenorhabditis elegans

open access: yesmBio, 2021
A variety of effector proteins contribute to host defense in the nematode Caenorhabditis ...
Wen Pan   +4 more
doaj   +1 more source

Conditional immobilization for live imaging Caenorhabditis elegans using auxin-dependent protein depletion

open access: yesG3: Genes, Genomes, Genetics, 2021
The visualization of biological processes using fluorescent proteins and dyes in living organisms has enabled numerous scientific discoveries.
Cori K Cahoon, Diana E Libuda
doaj   +1 more source

Genetic analysis suggests a surface of PAT-4 (ILK) that interacts with UNC-112 (kindlin)

open access: yesG3: Genes, Genomes, Genetics, 2022
Integrin plays a crucial role in the attachment of cells to the extracellular matrix. Integrin recruits many proteins intracellularly, including a 4-protein complex (kindlin, ILK, PINCH, and parvin).
Hiroshi Qadota   +6 more
doaj   +1 more source

Planococcus maritimus ML1206 Isolated from Wild Oysters Enhances the Survival of Caenorhabditis elegans against Vibrio anguillarum

open access: yesMarine Drugs, 2021
With the widespread occurrence of aquaculture diseases and the broad application of antibiotics, drug-resistant pathogens have increasingly affected aquatic animals’ health.
Ying-Xiu Li   +7 more
doaj   +1 more source

Comparative functional analysis of the Caenorhabditis elegans and Drosophila melanogaster proteomes. [PDF]

open access: yesPLoS Biology, 2009
The nematode Caenorhabditis elegans is a popular model system in genetics, not least because a majority of human disease genes are conserved in C. elegans.
Sabine P Schrimpf   +12 more
doaj   +1 more source

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