Results 1 to 10 of about 73,569 (303)
Nuclear/Cytoplasmic Fractionation of Proteins from Caenorhabditis elegans [PDF]
C. elegans is widely used to investigate biological processes related to health and disease. To study protein localization, fluorescently-tagged proteins can be used in vivo or immunohistochemistry can be performed in whole worms.
Alejandro Mata-Cabana +3 more
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An SRR1 domain-containing protein is required for efficient Orsay virus replication in Caenorhabditis elegans [PDF]
Viruses depend on their hosts for completing their life cycle, and a better understanding of virus replication can inform therapeutic strategies. Using the Orsay virus-Caenorhabditis elegans experimental platform, we identified by a forward genetic ...
Chika Fujii, David Wang
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Kinesins in Caenorhabditis elegans neuronal morphogenesis [PDF]
Neuronal morphogenesis is regulated by intracellular transport and cytoskeletal dynamics. Kinesin superfamily proteins (KIFs), or kinesins, function as molecular motors for intracellular transport and as regulators of the microtubule cytoskeleton, making
Shinsuke Niwa, Kyoko Chiba
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Recent progress in regulation of aging by non-coding RNAs in Caenorhabditis elegans [PDF]
Non-coding RNAs (ncRNAs) are RNA molecules that are not translated into proteins. Recent advances in RNA biology have uncovered roles of ncRNAs in physiological processes, including aging.
Seungjae Hwang +2 more
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Prereplication complex proteins get caught moonlighting
In this issue of PLOS Biology, Lattmann and colleagues report a new function for proteins of the DNA prereplication complex promoting the anchor cell to invade through the basement membrane and initiate vulval development in Caenorhabditis elegans.
Hilary A. Coller
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Identification and Functional Analysis of Cytokine-Like Protein CLEC-47 in Caenorhabditis elegans
A variety of effector proteins contribute to host defense in the nematode Caenorhabditis ...
Wen Pan +4 more
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The visualization of biological processes using fluorescent proteins and dyes in living organisms has enabled numerous scientific discoveries.
Cori K Cahoon, Diana E Libuda
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Genetic analysis suggests a surface of PAT-4 (ILK) that interacts with UNC-112 (kindlin)
Integrin plays a crucial role in the attachment of cells to the extracellular matrix. Integrin recruits many proteins intracellularly, including a 4-protein complex (kindlin, ILK, PINCH, and parvin).
Hiroshi Qadota +6 more
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With the widespread occurrence of aquaculture diseases and the broad application of antibiotics, drug-resistant pathogens have increasingly affected aquatic animals’ health.
Ying-Xiu Li +7 more
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Comparative functional analysis of the Caenorhabditis elegans and Drosophila melanogaster proteomes. [PDF]
The nematode Caenorhabditis elegans is a popular model system in genetics, not least because a majority of human disease genes are conserved in C. elegans.
Sabine P Schrimpf +12 more
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