Results 121 to 130 of about 1,676,429 (284)

Crosstalk Between Parkinson's Disease and Colorectal Cancer: Genetic Mechanisms, Gut Microbiota, and Therapeutic Insights

Health Care Science, EarlyView.
This review elucidates the crosstalk between Parkinson's disease and colorectal cancer, driven by shared genetics (PRKN, PINK1, DJ‐1) involving oxidative stress, cell cycle regulation, and inflammation. It identifies the gut microbiota—via functional amyloids and short‐chain fatty acids (SCFAs)—as a mechanistic bridge, offering insights for dual ...
Jiacheng Ying, Zhengyuan Fang, Cheng Zhang, Xu Liu, Jianzhi Cui, Zezhi Li, Jiayin Tang   +6 more
wiley   +1 more source

Unzipping the defense: a comprehensive review on bZIP transcription factors in Caenorhabditis elegans

Frontiers in Cellular and Infection Microbiology
Caenorhabditis elegans is a simple yet powerful host model organism for exploring how animals mount defenses against infection. In the absence of an adaptive immune system, it relies solely on innate immunity, making it an ideal model for studying ...
Boopathi Balasubramaniam, Ashley V. Veatch, Ransome van der Hoeven, Ransome van der Hoeven, Ransome van der Hoeven   +4 more
doaj   +1 more source

Multifaceted roles of CCAR family proteins in the DNA damage response and cancer

Experimental and Molecular Medicine
The cell cycle apoptosis regulator (CCAR) family of proteins consists of two proteins, CCAR1 and CCAR2, that play a variety of roles in cellular physiology and pathology. These multidomain proteins are able to perform multiple interactions and functions,
D. Lugano, L. Barrett, S. D. Westerheide, Y. Kee   +3 more
doaj   +1 more source

Patterns of nucleotide polymorphism distinguish temperate and tropical wild isolates of Caenorhabditis briggsae [PDF]

, 2006
Caenorhabditis briggsae provides a natural comparison species for the model nematode C. elegans, given their similar morphology, life history, and hermaphroditic mode of reproduction. Despite C.
Cutter, Asher, Cutter, Asher D., Felix, Marie-Anne, Barriere, Antoine, Charlesworth, Deborah   +4 more
core   +1 more source

Parental Exposure to Nanoplastics and Graphene Oxide Induces Transgenerational Toxicity in Caenorhabditis elegans

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental pollution by emerging contaminants such as nanoplastics (NPs) and graphene oxide (GO) represents a growing threat to global health and ecosystems. This study investigated the effects of parental exposure, both isolated and combined, to 100 μg/L NPs (polystyrene, spherical, 100 nm) and 100 mg/L GO, using Caenorhabditis elegans as ...
Gabriela Corrêa Soares, Larissa Müller, Suamy Machado Cruz, Andy Taipe Huisa, Danilo Roberto Carvalho Ferreira, Clascídia Aparecida Furtado, Juliane Ventura‐Lima   +6 more
wiley   +1 more source

Investigations on the functions ot "ten-1" during embryonic development in "Caenorhabditis" elegans [PDF]

, 2011
Teneurins are a family of phylogenetically conserved proteins. Their most prominent site of expression is the nervous system. Investigations on the expression pattern in vertebrates and invertebrates also revealed the importance for teneurins at sites of
Topf, Ulrike
core   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

A Reversible Clearing Strategy Enables Robust Label‐Free Phase Imaging of Thick Tissues

Laser &Photonics Reviews, EarlyView.
The principle of a reversible clearing strategy via glycerol and tartrazine solution (GTS) for robust whole‐slide label‐free phase imaging of thick tissue slices via high‐throughput Fourier ptychographic microscopy (FPM) and lensless digital holographic microscopy (LDHM). ABSTRACT Thick biological specimens impose strong scattering and attenuation that
Mikołaj Krysa, Anna Chwastowicz, Małgorzata Lenarcik, Paweł Matryba, Piotr Zdańkowski, Maciej Trusiak   +5 more
wiley   +1 more source

Kinesins in Caenorhabditis elegans neuronal morphogenesis

Open Biology
Neuronal morphogenesis is regulated by intracellular transport and cytoskeletal dynamics. Kinesin superfamily proteins (KIFs), or kinesins, function as molecular motors for intracellular transport and as regulators of the microtubule cytoskeleton, making
Shinsuke Niwa, Kyoko Chiba
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source